{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T04:30:12Z","timestamp":1769574612526,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:00Z","timestamp":1761264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Dapsone has been a quick and affordable treatment option for a diverse range of dermatological pathologies. Although licensed for the management of leprosy and dermatitis herpetiformis, its uses expand to a range of neutrophil- and eosinophil-driven pathologies. This retrospective study examined the use of dapsone at a large tertiary dermatology department in the UK serving a diverse population. In our report, we assess indications for use and treatment efficacy, and provide 3-year follow-up data on clinical outcomes and adverse events, and their frequency. These data demonstrate the unpredictable efficacy of dapsone, and allow dermatologists to better inform their patients regarding possible treatment success with dapsone, as well as to counsel patients regarding the frequency and range of possible adverse events.<\/jats:p>","DOI":"10.1093\/ced\/llaf464","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T12:22:57Z","timestamp":1761222177000},"page":"282-285","source":"Crossref","is-referenced-by-count":0,"title":["Dapsone use in dermatology: indication, efficacy and tolerability experience of a UK tertiary dermatology department"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1009-7819","authenticated-orcid":false,"given":"Zhao Xuan","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Dermatology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust , Birmingham ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Passby","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust , Birmingham ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"Button","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust , Birmingham ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shireen","family":"Velangi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust , Birmingham ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,24]]},"reference":[{"issue":"2","key":"2026012711323354800_llaf464-B1","article-title":"Dapsone","volume":"8","author":"Wolf","year":"2002","journal-title":"Dermatol Online J"},{"key":"2026012711323354800_llaf464-B2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00403-013-1409-7","article-title":"Dapsone in dermatology and beyond","volume":"306","author":"Wozel","year":"2014","journal-title":"Arch Dermatol Res"},{"key":"2026012711323354800_llaf464-B3","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s40257-024-00879-8","article-title":"Dapsone use in dermatology","volume":"25","author":"Lovell","year":"2024","journal-title":"Am J Clin Dermatol"},{"key":"2026012711323354800_llaf464-B4","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/S0049-0172(96)80004-7","article-title":"Dapsone in rheumatoid arthritis","volume":"25","author":"Chang","year":"1996","journal-title":"Semin Arthritis Rheum"},{"key":"2026012711323354800_llaf464-B5","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/ijd.14761","article-title":"Update on the use of dapsone in dermatology","volume":"59","author":"Ghaoui","year":"2020","journal-title":"Int J Dermatol"},{"key":"2026012711323354800_llaf464-B6","author":"University Hospitals Birmingham NHS Foundation Trust. Care Quality Commission"},{"key":"2026012711323354800_llaf464-B7","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.jaad.2010.09.777","article-title":"Dermatitis herpetiformis. Part I. Epidemiology, pathogenesis, and clinical presentation","volume":"64","author":"Bolotin","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"2026012711323354800_llaf464-B8","doi-asserted-by":"crossref","first-page":"713","DOI":"10.2165\/11536520-000000000-00000","article-title":"Medications and glucose-6-phosphate dehydrogenase deficiency: an evidence-based review","volume":"33","author":"Youngster","journal-title":"Drug Saf"},{"key":"2026012711323354800_llaf464-B9","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1080\/16078454.2022.2149943","article-title":"Dapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria","volume":"28","author":"Hu","year":"2022","journal-title":"Hematology"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llaf464\/64925322\/llaf464.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/51\/2\/282\/64925322\/llaf464.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/51\/2\/282\/64925322\/llaf464.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T16:32:42Z","timestamp":1769531562000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/51\/2\/282\/8301028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,24]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,10,24]]},"published-print":{"date-parts":[[2026,1,27]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llaf464","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2025,10,24]]}}}