{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T14:03:31Z","timestamp":1784901811503,"version":"3.55.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100000296","name":"British Skin Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000296","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Narrowband (NB)-ultraviolet B (UVB) is a second-line treatment for chronic moderate-to-severe atopic eczema unresponsive to adequate topical therapy, and is known to induce good short-term improvement of eczema severity. However, it is unclear how adult patients fare with their eczema severity long after completion of a course of NB-UVB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the severity of atopic eczema in adults, 1\u2005year following completion of NB-UVB, using validated clinical activity measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We undertook a multicentre prospective observational study of adults with moderate-to-severe atopic eczema who were prescribed NB-UVB as part of their standard clinical care. Assessments were made at baseline prior to starting NB-UVB, at the end of NB-UVB and at 4, 8 and 12\u2005months after completion of NB-UVB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty participants with moderate-to-severe atopic eczema [mean Objective SCORing Atopic Dermatitis (SCORAD) 39.2 (SD 12.8), Patient-Oriented Eczema Measure (POEM) 18.5 (SD 6.4) and\u00a0Investigator Global Assessment (IGA) 3.2 (SD 0.5)] underwent NB-UVB therapy. Significant reductions were observed post-treatment: Objective SCORAD decreased to 17.8 (SD 11.4), POEM to 8.2 (SD 6.2) and IGA to 1.7 (SD 1.0) (P &amp;lt; 0.001 achieved for all timepoints). These therapeutic effects were sustained at 4, 8 and 12\u2005months post-treatment (n = 27 at 12\u2005months). Loss to follow-up was attributed to nonattendance exacerbated by the COVID-19 pandemic and patient relocation. Mild adverse events (n = 5), including erythema and eczema flares, were reported, with no serious events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings indicate that NB-UVB may provide a long-lasting effect for patients who complete a course, helping to diminish their eczema severity to a more manageable level.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ced\/llag066","type":"journal-article","created":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T12:35:06Z","timestamp":1770554106000},"page":"1412-1418","source":"Crossref","is-referenced-by-count":0,"title":["Investigating the course of atopic eczema up to 1\u2005year following completion of narrowband ultraviolet B phototherapy"],"prefix":"10.1093","volume":"51","author":[{"given":"Sonali","family":"Bajaj","sequence":"first","affiliation":[{"name":"Department of Dermatology, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust , Darlington, Durham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prachi","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust , Darlington, Durham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akansha","family":"Singh","sequence":"additional","affiliation":[{"name":"Durham University , Durham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimple","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shrewsbury and Telford Hospital NHS Trust , Shrewsbury ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyamal","family":"Wahie","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust , Darlington, Durham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"2026072409164049200_llag066-B1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/jdv.14891","article-title":"Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I","volume":"32","author":"Wollenberg","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2026072409164049200_llag066-B2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1046\/j.1365-2133.2003.05403.x","article-title":"Dirt, worms and atopic dermatitis","volume":"148","author":"Flohr","year":"2003","journal-title":"Br J 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