{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:59:35Z","timestamp":1790351975185,"version":"4.1.0"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["NIHR203308"],"award-info":[{"award-number":["NIHR203308"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000276","name":"Department of Health and Social Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,25]]},"abstract":"<jats:p>We report an uncommon presentation of alopecia areata (AA) characterized by multiple hair shafts displaying segmental heterochromia and calibre change. The pigmentary and calibre changes suggest an intermittent low-level inflammatory process in diffuse AA, with periods of recovery where the hair fibre regains its normal characteristics.<\/jats:p>","DOI":"10.1093\/ced\/llag228","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T11:39:16Z","timestamp":1780745956000},"page":"1968-1970","source":"Crossref","is-referenced-by-count":0,"title":["Segmental heterochromia with calibre change: a rare sign of alopecia areata"],"prefix":"10.1093","volume":"51","author":[{"given":"Thomas","family":"Harries","sequence":"first","affiliation":[{"name":"Newcastle Medical School , Newcastle\u00a0Upon\u00a0Tyne ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0563-8690","authenticated-orcid":false,"given":"Matthew","family":"Harries","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre , Manchester ,","place":["UK"]},{"name":"Centre for Dermatology Research, Faculty of Biology, Medicine and Health, University of Manchester, and NIHR Manchester Biomedical Research Centre , Manchester ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,8]]},"reference":[{"key":"2026092511023217400_llag228-B1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1001\/archderm.1989.01670160079015","article-title":"Segmented heterochromia in black scalp hair associated with iron-deficiency anemia. Canities segmentata sideropaenica","volume":"125","author":"Sato","year":"1989","journal-title":"Arch Dermatol"},{"key":"2026092511023217400_llag228-B2","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.jaad.2018.12.047","article-title":"White hair in alopecia areata: clinical forms and proposed physiopathologic mechanisms","volume":"89","author":"Asz-Sigall","year":"2023","journal-title":"J Am Acad Dermatol"},{"key":"2026092511023217400_llag228-B3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1365-2133.1984.tb07461.x","article-title":"Alopecia areata: light and electron microscopic pathology of the regrowing white hair","volume":"110","author":"Messenger","year":"1984","journal-title":"Br J Dermatol"},{"key":"2026092511023217400_llag228-B4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/exd.13799","article-title":"Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time","volume":"29","author":"Zhang","year":"2020","journal-title":"Exp Dermatol"},{"key":"2026092511023217400_llag228-B5","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1365-2133.1984.tb06637.x","article-title":"Coudability\u2019: a new physical sign of alopecia areata","volume":"111","author":"Shuster","year":"1984","journal-title":"Br J Dermatol"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llag228\/68487130\/llag228.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/51\/10\/1968\/68487130\/llag228.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/51\/10\/1968\/68487130\/llag228.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:02:41Z","timestamp":1790348561000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/51\/10\/1968\/8703647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,8]]},"references-count":5,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,6,8]]},"published-print":{"date-parts":[[2026,9,25]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llag228","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10]]},"published":{"date-parts":[[2026,6,8]]}}}