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The PPC is known to receive inputs from a collection of sensory cortices as well as various subcortical areas and integrate those inputs to facilitate the execution of functions that require diverse information. Although many recent works have been performed with the mouse as a model system, a comprehensive understanding of long-range connectivity of the mouse PPC is scarce, preventing integrative interpretation of the rapidly accumulating functional data. In this study, we conducted a detailed neuroanatomic and bioinformatic analysis of the Allen Mouse Brain Connectivity Atlas data to summarize afferent and efferent connections to\/from the PPC. Then, we analyzed variability between subregions of the PPC, functional\/anatomical modalities, and species, and summarized the organizational principle of the mouse PPC. Finally, we confirmed key results by using additional neurotracers. A comprehensive survey of the connectivity will provide an important future reference to comprehend the function of the PPC and allow effective paths forward to various studies using mice as a model system.<\/jats:p>","DOI":"10.1093\/cercor\/bhaa230","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T19:25:25Z","timestamp":1596569125000},"page":"356-378","source":"Crossref","is-referenced-by-count":12,"title":["Comprehensive Analysis of Long-Range Connectivity from and to the Posterior Parietal Cortex of the Mouse"],"prefix":"10.1093","volume":"31","author":[{"given":"Seung Wook","family":"Oh","sequence":"first","affiliation":[{"name":"Grace Medical Institute, Lynnwood, WA 98037, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sook Jin","family":"Son","sequence":"additional","affiliation":[{"name":"Laboratory of Neurophysiology, Korea Brain Research Institute, Daegu 41062, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A","family":"Morris","sequence":"additional","affiliation":[{"name":"Grace Medical Institute, Lynnwood, WA 98037, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Laboratory of Neurophysiology, Korea Brain Research Institute, Daegu 41062, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changkyu","family":"Lee","sequence":"additional","affiliation":[{"name":"Allen Institute for Brain Science, Seattle, WA 98109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3780-0522","authenticated-orcid":false,"given":"Jong-Cheol","family":"Rah","sequence":"additional","affiliation":[{"name":"Laboratory of Neurophysiology, Korea Brain Research Institute, Daegu 41062, Korea"},{"name":"Department of Brain and Cognitive Sciences, DGIST, Daegu 42988, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,10,15]]},"reference":[{"key":"2020121009240828200_ref1","first-page":"179","article-title":"Cortical efferents of the perirhinal, postrhinal, and entorhinal cortices of the rat","volume":"19","author":"Agster","year":"1998","journal-title":"J Comp Neurol."},{"key":"2020121009240828200_ref3","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1093\/cercor\/bhm138","article-title":"Information processing streams in rodent barrel cortex: the differential functions of barrel and septal circuits","volume":"18","author":"Alloway","year":"2008","journal-title":"Cereb Cortex."},{"key":"2020121009240828200_ref4","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1111\/j.1460-9568.2010.07264.x","article-title":"Long-range connectivity of mouse primary somatosensory barrel cortex","volume":"31","author":"Aronoff","year":"2010","journal-title":"Eur J Neurosci."},{"key":"2020121009240828200_ref5","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1093\/cercor\/bhx044","article-title":"POm thalamocortical input drives layer-specific microcircuits in somatosensory cortex","volume":"28","author":"Audette","year":"2018","journal-title":"Cereb Cortex."},{"key":"2020121009240828200_ref6","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nature09802","article-title":"Network anatomy and in vivo physiology of visual cortical neurons","volume":"471","author":"Bock","year":"2011","journal-title":"Nature."},{"key":"2020121009240828200_ref7","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/nn.4568","article-title":"Thalamic projections sustain prefrontal activity during working memory maintenance","volume":"20","author":"Bolkan","year":"2017","journal-title":"Nat Neurosci."},{"key":"2020121009240828200_ref8","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/cne.21209","article-title":"Online workbenches for neural network connections","volume":"500","author":"Bota","year":"2007","journal-title":"J Comp Neurol."},{"key":"2020121009240828200_ref9","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/(SICI)1096-9861(19980112)390:2<297::AID-CNE11>3.0.CO;2-V","article-title":"Backward cortical projections to primary somatosensory cortex in rats extend long horizontal axons in layer I","volume":"390","author":"Cauller","year":"1998","journal-title":"J Comp Neurol."},{"key":"2020121009240828200_ref10","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0304-3940(92)90273-A","article-title":"Thalamocortical connections of rat posterior parietal cortex","volume":"143","author":"Chandler","year":"1992","journal-title":"Neurosci Lett."},{"key":"2020121009240828200_ref11","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF00243212","article-title":"Head-direction cells in the rat posterior cortex. 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