{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T21:58:17Z","timestamp":1753739897173,"version":"3.37.3"},"reference-count":106,"publisher":"Oxford University Press (OUP)","issue":"14","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Previous studies suggest there is a complex relationship between sexual and general affective stimulus processing, which varies across individuals and situations. We examined whether sexual and general affective processing can be distinguished at the brain level. In addition, we explored to what degree possible distinctions are generalizable across individuals and different types of sexual stimuli, and whether they are limited to the engagement of lower-level processes, such as the detection of visual features. Data on sexual images, nonsexual positive and negative images, and neutral images from Wehrum et\u00a0al. (2013) (N\u2009=\u2009100) were reanalyzed using multivariate support vector machine models to create the brain activation-based sexual image classifier (BASIC) model. This model was tested for sensitivity, specificity, and generalizability in cross-validation (N\u2009=\u2009100) and an independent test cohort (N\u2009=\u200918; Kragel et\u00a0al. 2019). The BASIC model showed highly accurate performance (94\u2013100%) in classifying sexual versus neutral or nonsexual affective images in both datasets with forced choice tests. Virtual lesions and tests of individual large-scale networks (e.g., visual or attention networks) show that individual networks are neither necessary nor sufficient to classify sexual versus nonsexual stimulus processing. Thus, responses to sexual images are distributed across brain systems.<\/jats:p>","DOI":"10.1093\/cercor\/bhab397","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T20:14:43Z","timestamp":1637007283000},"page":"3014-3030","source":"Crossref","is-referenced-by-count":5,"title":["The brain activation-based sexual image classifier (BASIC): a sensitive and specific fMRI activity pattern for sexual image processing"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1758-8966","authenticated-orcid":false,"given":"Sophie R","family":"van \u2019t Hof","sequence":"first","affiliation":[{"name":"Department of Psychological and Brain Sciences , , Hanover, NH 03755, USA"},{"name":"Dartmouth College , , Hanover, NH 03755, USA"},{"name":"Department of Psychiatry , , 1105 AZ, The Netherlands"},{"name":"Amsterdam Medical Centre , , 1105 AZ, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Van Oudenhove","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences , , Hanover, NH 03755, USA"},{"name":"Dartmouth College , , Hanover, NH 03755, USA"},{"name":"Laboratory for Brain-Gut Axis Studies, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases and Metabolism, KU Leuven , Leuven 3000, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erick","family":"Janssen","sequence":"additional","affiliation":[{"name":"Institute for Family and Sexuality Studies, KU Leuven , Leuven 3000, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja","family":"Klein","sequence":"additional","affiliation":[{"name":"Bender Institute of Neuroimaging (BION), Justus Liebig University Giessen , Giessen 35390, Germany"},{"name":"Department of Psychotherapy and Systems Neuroscience , , Giessen 35390, Germany"},{"name":"Justus Liebig University Giessen , , Giessen 35390, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne C","family":"Reddan","sequence":"additional","affiliation":[{"name":"Institute of Cognitive Science , Department of Psychology and Neuroscience, , Boulder, CO 80309, USA"},{"name":"University of Colorado Boulder , Department of Psychology and Neuroscience, , Boulder, CO 80309, USA"},{"name":"Stanford University , Palo Alto, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip A","family":"Kragel","sequence":"additional","affiliation":[{"name":"Institute of Cognitive Science , Department of Psychology and Neuroscience, , Boulder, CO 80309, USA"},{"name":"University of Colorado Boulder , Department of Psychology and Neuroscience, , Boulder, CO 80309, USA"},{"name":"Emory University , Atlanta, GA, 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