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As cortical thickness is commonly used as a proxy to identify cortical regions that have undergone plastic changes, the purpose of this investigation was to compare cortical thickness patterns between hearing and deaf cats. In this study, normal hearing (n\u2009=\u200929) and deaf (n\u2009=\u200926) cats were scanned to examine cortical thickness in hearing controls, as well as differential changes in thickness as a consequence of deafness. In hearing cats, a gradient in cortical thickness was identified across auditory cortex in which it is thinner in more dorsal regions and thicker in more ventral regions. Compared with hearing controls, differential thickening and thinning was observed in specific regions of deaf auditory cortex. More dorsal regions were found to be bilaterally thicker in the deaf group, while more ventral regions in the left hemisphere were thinner. The location and nature of these changes creates a gradient along the dorsoventral axis, wherein dorsal auditory cortical fields are thicker, whereas more ventral fields are thinner in deaf animals compared with hearing controls.<\/jats:p>","DOI":"10.1093\/cercor\/bhac463","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T07:26:17Z","timestamp":1670570777000},"page":"5829-5838","source":"Crossref","is-referenced-by-count":7,"title":["The gradient in gray matter thickness across auditory cortex and differential cortical thickness changes following perinatal deafness"],"prefix":"10.1093","volume":"33","author":[{"given":"Stephen G","family":"Gordon","sequence":"first","affiliation":[{"name":"Integrated Program in Neuroscience, McGill University , Montreal, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blake E","family":"Butler","sequence":"additional","affiliation":[{"name":"Department of Psychology, Western University , 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