{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:16:39Z","timestamp":1787008599498,"version":"build-2736575974"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:00:00Z","timestamp":1699401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"publisher","award":["8200675"],"award-info":[{"award-number":["8200675"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170686"],"award-info":[{"award-number":["82170686"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"GYC","award":["22KJLJ001"],"award-info":[{"award-number":["22KJLJ001"]}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFA0108803"],"award-info":[{"award-number":["2018YFA0108803"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Postgraduate Research & Practice Innovation Program of Jiangsu Province","award":["KYCX21_0225"],"award-info":[{"award-number":["KYCX21_0225"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the effects of peritoneal dialysis and hemodialysis on spontaneous brain activity in patients with end-stage renal disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 52 dialysis patients with end-stage renal disease, including 25 patients with chronic kidney disease undergoing hemodialysis (HD-CKD) and 27 patients with chronic kidney disease undergoing peritoneal dialysis (PD-CKD), and 49 healthy controls (normal control) were included. All participants underwent neuropsychological testing (Mini-Mental State Examination and Montreal cognitive assessment) and resting-state functional magnetic resonance imaging. Fractional amplitude of low frequency fluctuations and Regional Homogeneity algorithms were employed to evaluate spontaneous brain activity. Statistical analysis was performed to discern differences between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>When compared with the normal control group, the PD-CKD group exhibited significant alterations in fractional amplitude of low frequency fluctuations in various cerebellum regions and other brain areas, while the HD-CKD group showed decreased fractional amplitude of low frequency fluctuations in the bilateral pericalcarine cortex. The Regional Homogeneity values in the PD-CKD group were notably different than those in the normal control group, particularly in regions such as the bilateral caudate nucleus and the right putamen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both peritoneal dialysis and hemodialysis modalities impact brain activity, but manifest differently in end-stage renal disease patients. Understanding these differences is crucial for optimizing patient care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/cercor\/bhad377","type":"journal-article","created":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T08:27:38Z","timestamp":1696667258000},"source":"Crossref","is-referenced-by-count":10,"title":["Comparison of the effects of peritoneal dialysis and hemodialysis on spontaneous brain activity in CKD patients: an rs-fMRI study"],"prefix":"10.1093","volume":"34","author":[{"given":"Chaoyang","family":"Zhang","sequence":"first","affiliation":[{"name":"Medical School of Chinese PLA , Beijing 100853, China"},{"name":"First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People\u2019s Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , Beijing 100853, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Nephrology, The Affiliated Hospital of Yangzhou University , Yangzhou 225001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Liangxiang Hospital , Fangshan District, Beijing 102488, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, Yanjing Medical College, Capital Medical University , Beijing 100069, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiexi","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics , Nanjing 210016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Liang","sequence":"additional","affiliation":[{"name":"Medical School of Chinese PLA , Beijing 100853, China"},{"name":"First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People\u2019s Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , Beijing 100853, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Medical School of Chinese PLA , Beijing 100853, China"},{"name":"First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People\u2019s Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , Beijing 100853, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyu","family":"Duan","sequence":"additional","affiliation":[{"name":"Medical School of Chinese PLA , Beijing 100853, China"},{"name":"First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People\u2019s Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , Beijing 100853, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Zhang","sequence":"additional","affiliation":[{"name":"Medical School of Chinese PLA , Beijing 100853, China"},{"name":"First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People\u2019s Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , Beijing 100853, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyan","family":"Cai","sequence":"additional","affiliation":[{"name":"Medical School of Chinese PLA , Beijing 100853, China"},{"name":"First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People\u2019s Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , Beijing 100853, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,8]]},"reference":[{"issue":"4","key":"2024011713071424200_ref1","doi-asserted-by":"crossref","first-page":"R136","DOI":"10.1016\/j.cub.2009.12.014","article-title":"Working memory","volume":"20","author":"Baddeley","year":"2010","journal-title":"Curr Biol"},{"issue":"5","key":"2024011713071424200_ref2","first-page":"759","article-title":"Cognitive impairments and associated factors in community-dwelling elderly in Chengdu, Sichuan","volume":"49","author":"Bo","year":"2018","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"},{"issue":"3","key":"2024011713071424200_ref3","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/gerona\/glx241","article-title":"Prevalence and risk of severe cognitive impairment in advanced chronic kidney disease","volume":"73","author":"Burns","year":"2018","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2024011713071424200_ref4","doi-asserted-by":"crossref","first-page":"569806","DOI":"10.3389\/fneur.2020.569806","article-title":"Abnormal default-mode network homogeneity in patients with mild cognitive impairment in Chinese communities","volume":"11","author":"Cao","year":"2020","journal-title":"Front Neurol"},{"key":"2024011713071424200_ref5","doi-asserted-by":"crossref","first-page":"1040553","DOI":"10.3389\/fnhum.2022.1040553","article-title":"Alterations of amplitude of low-frequency fluctuations and fractional amplitude of low-frequency fluctuations in end-stage renal disease on maintenance dialysis: an activation likelihood estimation meta-analysis","volume":"16","author":"Cao","year":"2022","journal-title":"Front Hum Neurosci"},{"key":"2024011713071424200_ref6","doi-asserted-by":"crossref","first-page":"401","DOI":"10.3389\/fpsyg.2018.00401","article-title":"Working memory from the psychological and neurosciences perspectives: a review","volume":"9","author":"Chai","year":"2018","journal-title":"Front Psychol"},{"key":"2024011713071424200_ref7","doi-asserted-by":"crossref","first-page":"656","DOI":"10.3389\/fpsyg.2020.00656","article-title":"Altered spontaneous neural activity in peripartum depression: a resting-state functional magnetic resonance imaging study","volume":"11","author":"Che","year":"2020","journal-title":"Front Psychol"},{"issue":"5","key":"2024011713071424200_ref8","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1007\/s11011-015-9702-0","article-title":"The impact of hemodialysis on cognitive dysfunction in patients with end-stage renal disease: a resting-state functional MRI study","volume":"30","author":"Chen","year":"2015","journal-title":"Metab Brain Dis"},{"issue":"1","key":"2024011713071424200_ref9","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/kisup.2015.2","article-title":"United States Renal Data System public health surveillance of chronic kidney disease and end-stage renal disease","volume":"5","author":"Collins","year":"2015","journal-title":"Kidney Int Suppl (2011)"},{"issue":"2","key":"2024011713071424200_ref10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1053\/j.ajkd.2014.07.009","article-title":"Cognitive function and all-cause mortality in maintenance hemodialysis patients","volume":"65","author":"Drew","year":"2015","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"2024011713071424200_ref12","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1053\/j.ajkd.2018.02.361","article-title":"Cognitive impairment in non-dialysis-dependent CKD and the transition to dialysis: findings from the Chronic Renal Insufficiency Cohort (CRIC) study","volume":"72","author":"Harhay","year":"2018","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"2024011713071424200_ref13","doi-asserted-by":"crossref","first-page":"445","DOI":"10.31887\/DCNS.2013.15.4\/hjahn","article-title":"Memory loss in Alzheimer's disease","volume":"15","author":"Jahn","year":"2013","journal-title":"Dialogues Clin Neurosci"},{"issue":"1","key":"2024011713071424200_ref14","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1053\/j.ajkd.2016.01.026","article-title":"Cognitive impairment and progression of CKD","volume":"68","author":"Kurella Tamura","year":"2016","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"2024011713071424200_ref15","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1212\/WNL.54.4.849","article-title":"Mapping of functional organization in human visual cortex: electrical cortical stimulation","volume":"54","author":"Lee","year":"2000","journal-title":"Neurology"},{"issue":"4","key":"2024011713071424200_ref16","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1053\/j.ajkd.2008.06.023","article-title":"Variability and risk factors for kidney disease progression and death following attainment of stage 4 CKD in a referred cohort","volume":"52","author":"Levin","year":"2008","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"2024011713071424200_ref17","doi-asserted-by":"crossref","first-page":"e87114","DOI":"10.1371\/journal.pone.0087114","article-title":"Regional homogeneity changes in hemodialysis patients with end stage renal disease: in vivo resting-state functional MRI study","volume":"9","author":"Li","year":"2014","journal-title":"PLoS One"},{"key":"2024011713071424200_ref18","doi-asserted-by":"crossref","first-page":"852822","DOI":"10.3389\/fnins.2022.852822","article-title":"Abnormal dynamic functional connectivity in patients with end-stage renal disease","volume":"16","author":"Li","year":"2022","journal-title":"Front Neurosci"},{"issue":"4","key":"2024011713071424200_ref19","doi-asserted-by":"crossref","first-page":"e305","DOI":"10.1002\/mco2.305","article-title":"The reconfiguration pattern of individual brain metabolic connectome for Parkinson's disease identification","volume":"4","author":"Li","year":"2023","journal-title":"MedComm"},{"key":"2024011713071424200_ref20","doi-asserted-by":"crossref","first-page":"688376","DOI":"10.3389\/fpsyg.2021.688376","article-title":"Facial expression recognition and ReHo analysis in major depressive disorder","volume":"12","author":"Liu","year":"2021","journal-title":"Front Psychol"},{"issue":"8","key":"2024011713071424200_ref21","first-page":"1390","article-title":"Resting-state functional MRI: everything that nonexperts have always wanted to know","volume":"39","author":"Lv","year":"2018","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024011713071424200_ref22","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.neuroimage.2018.02.042","article-title":"Segregation of the human basal forebrain using resting state functional MRI","volume":"173","author":"Markello","year":"2018","journal-title":"NeuroImage"},{"issue":"2","key":"2024011713071424200_ref23","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s00062-020-00915-0","article-title":"Immediate abnormal intrinsic brain activity patterns in patients with end-stage renal disease during a single dialysis session: resting-state functional MRI study","volume":"31","author":"Peng","year":"2021","journal-title":"Clin Neuroradiol"},{"issue":"1","key":"2024011713071424200_ref24","doi-asserted-by":"crossref","first-page":"A6","DOI":"10.1053\/j.ajkd.2019.09.003","article-title":"US Renal Data System 2019 annual data report: epidemiology of kidney disease in the United States","volume":"75","author":"Saran","year":"2020","journal-title":"Am J Kidney Dis"},{"key":"2024011713071424200_ref25","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.neulet.2018.07.005","article-title":"The cerebellum and cognition","volume":"688","author":"Schmahmann","year":"2019","journal-title":"Neurosci Lett"},{"issue":"10","key":"2024011713071424200_ref26","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s10157-019-01762-1","article-title":"Prevalence of cognitive impairment among peritoneal dialysis patients: a systematic review and meta-analysis","volume":"23","author":"Shea","year":"2019","journal-title":"Clin Exp Nephrol"},{"issue":"10","key":"2024011713071424200_ref27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106700","article-title":"The Montreal Cognitive Assessment (MoCA) - a sensitive screening instrument for detecting cognitive impairment in chronic hemodialysis patients","volume":"9","author":"Tiffin-Richards","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"2024011713071424200_ref11","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.2337\/db11-1358","article-title":"Resting-state brain networks in type 1 diabetic patients with and without microangiopathy and their relation to cognitive functions and disease variables","volume":"61","author":"Duinkerken","year":"2012","journal-title":"Diabetes"},{"issue":"7","key":"2024011713071424200_ref30","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1093\/ndt\/gfx314","article-title":"Prevalence and patterns of cognitive impairment in adult hemodialysis patients: the COGNITIVE-HD study","volume":"33","author":"Zwieten","year":"2018","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"2024011713071424200_ref28","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1053\/j.ajkd.2018.04.020","article-title":"Cognitive changes in peritoneal dialysis patients: a multicenter prospective cohort study","volume":"72","author":"Zhang","year":"2018","journal-title":"Am J Kidney Dis"},{"key":"2024011713071424200_ref29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jns.2018.01.010","article-title":"Altered spontaneous brain activity in MRI-negative refractory temporal lobe epilepsy patients with major depressive disorder: a resting-state fMRI study","volume":"386","author":"Zhu","year":"2018","journal-title":"J Neurol Sci"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cercor\/article-pdf\/34\/1\/bhad377\/56131951\/bhad377.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cercor\/article-pdf\/34\/1\/bhad377\/56131951\/bhad377.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T08:07:50Z","timestamp":1705478870000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cercor\/article\/doi\/10.1093\/cercor\/bhad377\/7381656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,8]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1,14]]}},"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhad377","relation":{},"ISSN":["1047-3211","1460-2199"],"issn-type":[{"value":"1047-3211","type":"print"},{"value":"1460-2199","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1]]},"published":{"date-parts":[[2023,11,8]]},"article-number":"bhad377"}}