{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T15:35:04Z","timestamp":1780328104444,"version":"3.54.1"},"reference-count":155,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Focal cortical dysplasias are abnormalities of the cerebral cortex associated with an elevated risk of neurological disturbances. Cortical spreading depolarization\/depression is a correlate of migraine aura\/headache and a trigger of migraine pain mechanisms. However, cortical spreading depolarization\/depression is associated with cortical structural changes, which can be classified as transient focal cortical dysplasias. Migraine is reported to be associated with changes in various brain structures, including malformations and lesions in the cortex. Such malformations may be related to focal cortical dysplasias, which may play a role in migraine pathogenesis. Results obtained so far suggest that focal cortical dysplasias may belong to the causes and consequences of migraine. Certain focal cortical dysplasias may lower the threshold of cortical excitability and facilitate the action of migraine triggers. Migraine prevalence in epileptic patients is higher than in the general population, and focal cortical dysplasias are an established element of epilepsy pathogenesis. In this narrative\/hypothesis review, we present mainly information on cortical structural changes in migraine, but studies on structural alterations in deep white matter and other brain regions are also presented. We develop the hypothesis that focal cortical dysplasias may be causally associated with migraine and link pathogeneses of migraine and epilepsy.<\/jats:p>","DOI":"10.1093\/cercor\/bhae158","type":"journal-article","created":{"date-parts":[[2024,4,14]],"date-time":"2024-04-14T06:27:28Z","timestamp":1713076048000},"source":"Crossref","is-referenced-by-count":1,"title":["Potential of focal cortical dysplasia in migraine pathogenesis"],"prefix":"10.1093","volume":"34","author":[{"given":"Michal","family":"Fila","sequence":"first","affiliation":[{"name":"Department of Developmental Neurology and Epileptology, Polish Mother\u2019s Memorial Hospital Research Institute , Rzgowska 281\/289, 93-338 Lodz, \u0141\u00f3dzkie , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukasz","family":"Przyslo","sequence":"additional","affiliation":[{"name":"Department of Developmental Neurology and Epileptology, Polish Mother\u2019s Memorial Hospital Research Institute , Rzgowska 281\/289, 93-338 Lodz, \u0141\u00f3dzkie , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Derwich","sequence":"additional","affiliation":[{"name":"Department of Developmental Dentistry, Medical University of Lodz , Pomorska 251, 90-647 Lodz, \u0141\u00f3dzkie , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezbieta","family":"Pawlowska","sequence":"additional","affiliation":[{"name":"Department of Developmental Dentistry, Medical University of Lodz , Pomorska 251, 90-647 Lodz, \u0141\u00f3dzkie , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"Blasiak","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Collegium Medicum, , Plac Genera\u0142a Dabrowskiego 2, 09-420 Plock, Mazowieckie , Poland"},{"name":"Mazovian Academy in Plock , Collegium Medicum, , Plac Genera\u0142a Dabrowskiego 2, 09-420 Plock, Mazowieckie , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,13]]},"reference":[{"key":"2024041406272195100_ref1","first-page":"1","volume-title":"The international classification of headache disorders","author":"2018. 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