{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T01:55:28Z","timestamp":1783389328664,"version":"3.54.6"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"National Institute for Deafness and Communication","award":["DC 04845"],"award-info":[{"award-number":["DC 04845"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The study of the amygdala and its role in the processing of emotions has become a common focus in neuroscience. The modern expansion of research in this area is partly due to the discovery of a subcortical pathway for the transmission of emotional information and the experimental paradigm that was developed to study it. Groundbreaking experiments during the 90s utilized anatomical, neurophysiological, and behavioral lesion studies in a rodent animal model to uncover the neural circuitry of a simple emotional memory. These studies demonstrated the essential role of a specific monosynaptic pathway in emotional memory, using traditional tools and behavioral methods. The development of an animal model with a simple and appropriate classical conditioning paradigm made experimental investigations into the neural basis of emotion tenable and available to a generation of neuroscientists. These tools and a focus on the amygdala\u2019s neural connections and their essential role in emotional memory were a driving force in the explosion of research regarding the amygdala and emotion.<\/jats:p>","DOI":"10.1093\/cercor\/bhae408","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T13:20:37Z","timestamp":1728652837000},"page":"3-4","source":"Crossref","is-referenced-by-count":1,"title":["Gateway to the study of the amygdala and emotion"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7847-321X","authenticated-orcid":false,"given":"Lizabeth M","family":"Romanski","sequence":"first","affiliation":[{"name":"Department of Neuroscience, University of Rochester School of Medicine and Dentistry , 601 Elmwood Avenue, Rochester, NY 14642,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,11]]},"reference":[{"key":"2025010910353623000_ref1","doi-asserted-by":"publisher","first-page":"2818","DOI":"10.1523\/JNEUROSCI.10-08-02818.1990","article-title":"Synaptic plasticity in fear conditioning circuits: induction of LTP in the lateral nucleus of the amygdala by stimulation of the medial geniculate body","volume":"10","author":"Clugnet","year":"1990","journal-title":"J Neurosci"},{"key":"2025010910353623000_ref2","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1523\/JNEUROSCI.10-04-01055.1990","article-title":"Unit responses evoked in the amygdala and striatum by electrical stimulation of the medial geniculate body","volume":"10","author":"Clugnet","year":"1990","journal-title":"J Neurosci"},{"key":"2025010910353623000_ref3","doi-asserted-by":"publisher","first-page":"2871","DOI":"10.1073\/pnas.1400335111","article-title":"Coming to terms with fear","volume":"111","author":"LeDoux","year":"2014","journal-title":"Proc Natl Acad Sci"},{"key":"2025010910353623000_ref4","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1126\/science.6867731","article-title":"Local cerebral blood flow increases during auditory and emotional processing in the conscious rat","volume":"221","author":"LeDoux","year":"1983","journal-title":"Science"},{"key":"2025010910353623000_ref5","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1002\/cne.902420204","article-title":"Projections to the subcortical forebrain from anatomically defined regions of the medial geniculate body in the rat","volume":"242","author":"LeDoux","year":"1985","journal-title":"J Comp Neurol"},{"key":"2025010910353623000_ref6","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1111\/j.1749-6632.1985.tb37611.x","article-title":"Auditory emotional memories: establishment by projections from the medial geniculate nucleus to the posterior neostriatum and\/or dorsal amygdala","volume":"444","author":"LeDoux","year":"1985","journal-title":"Ann N Y Acad Sci"},{"key":"2025010910353623000_ref7","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1523\/JNEUROSCI.10-04-01062.1990","article-title":"The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning","volume":"10","author":"LeDoux","year":"1990","journal-title":"J Neurosci"},{"key":"2025010910353623000_ref8","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1523\/JNEUROSCI.10-04-01043.1990","article-title":"Topographic organization of neurons in the acoustic thalamus that project to the amygdala","volume":"10","author":"LeDoux","year":"1990","journal-title":"J Neurosci"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cercor\/article-pdf\/35\/1\/3\/59718022\/bhae408.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cercor\/article-pdf\/35\/1\/3\/59718022\/bhae408.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T10:35:53Z","timestamp":1736418953000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cercor\/article\/35\/1\/3\/7817846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,11]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,8]]}},"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhae408","relation":{},"ISSN":["1047-3211","1460-2199"],"issn-type":[{"value":"1047-3211","type":"print"},{"value":"1460-2199","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,1]]},"published":{"date-parts":[[2024,10,11]]}}}