{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:46:53Z","timestamp":1789454813208,"version":"build-2803163510"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"University of Alabama College Academy of Research, Scholarship, and Creative Activity"},{"name":"University of Alabama, Birmingham"},{"DOI":"10.13039\/100000002","name":"The National Institutes of Health","doi-asserted-by":"crossref","award":["P30AG031054"],"award-info":[{"award-number":["P30AG031054"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Episodic memory is the ability to bind elements of an experience into coherent associations. This ability declines with age, often producing errors that can interfere with daily life. Memory distortions might arise from unstable hippocampal representations that cannot be maintained across encoding, storage, and later retrieval. However, whether aging disrupts the temporal continuity of these representations across memory phases has not been directly tested. Here, adults aged 20\u201374 completed functional magnetic resonance imaging (fMRI) scanning during an associative memory task involving face\u2013object and face\u2013scene pairings, followed by post-encoding rest and a cued retrieval test. Using multivoxel correlation structure analyses, we quantified hippocampal pattern similarity across each memory stage. Increasing age was associated with increased category errors and reduced representational similarity across all transitions. Higher encoding\u2013retrieval similarity predicted better associative accuracy in younger adults and was less predictive in middle-aged and diminished in older adults. Uniquely among older adults, greater cross-phase similarity predicted elevated category-level binding errors, suggesting a shift from selective reactivation to misbinding with age. Baseline hippocampal organization and encoding-specific connectivity supported accurate reinstatement only in younger adults. Aging disrupts hippocampal stability, possibly representing a core mechanism of age-related decline in associative memory across the adult lifespan.<\/jats:p>","DOI":"10.1093\/cercor\/bhag114","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:58:08Z","timestamp":1783598288000},"source":"Crossref","is-referenced-by-count":1,"title":["Aging shifts hippocampal reactivation from selective reinstatement to category-level misbinding during episodic memory"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2598-9036","authenticated-orcid":false,"given":"Destaw B","family":"Mekbib","sequence":"first","affiliation":[{"name":"Department of Psychology, Binghamton University , 4400 Vestal Parkway East, Binghamton, NY 13902 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0907-8931","authenticated-orcid":false,"given":"Ian M","family":"McDonough","sequence":"additional","affiliation":[{"name":"Department of Psychology, Binghamton University , 4400 Vestal Parkway East, Binghamton, NY 13902 ,","place":["United States"]},{"name":"Center for Cognitive Applications, Binghamton University , 4400 Vestal Parkway East, Binghamton, NY 13902 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"2026081016385756200_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/gbae063","article-title":"Age deficits in associative memory are not alleviated by multisensory paradigms","volume":"79","author":"Badham","year":"2024","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"key":"2026081016385756200_ref2","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1177\/09637214241263020","article-title":"Hyper-binding: older adults form too many associations, not too 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