{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T08:09:38Z","timestamp":1790064578551,"version":"4.0.1"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1093\/cercor\/bhp009","type":"journal-article","created":{"date-parts":[[2009,2,22]],"date-time":"2009-02-22T03:42:00Z","timestamp":1235274120000},"page":"2196-2207","source":"Crossref","is-referenced-by-count":90,"title":["Selective Depletion of Molecularly Defined Cortical Interneurons in Human Holoprosencephaly with Severe Striatal Hypoplasia"],"prefix":"10.1093","volume":"19","author":[{"given":"Sofia","family":"Fertuzinhos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u017deljka","family":"Krsnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuka Imamura","family":"Kawasawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mladen-Roko","family":"Ra\u0161in","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth Y.","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie-Guang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milo\u0161","family":"Juda\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaharu","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nenad","family":"\u0160estan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,2,20]]},"reference":[{"key":"key\n\t\t\t\t20170521001833_bib1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1126\/science.278.5337.474","article-title":"Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes","volume":"278","author":"Anderson","year":"1997","journal-title":"Science"},{"key":"key\n\t\t\t\t20170521001833_bib2","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/s004010000184","article-title":"Ectopic expression of telencephalin in brains with holoprosencephaly","volume":"100","author":"Arii","year":"2000","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170521001833_bib3","first-page":"431","article-title":"Middle interhemispheric fusion: an unusual variant of holoprosencephaly","volume":"14","author":"Barkovich","year":"1993","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170521001833_bib4","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.1469-7580.2007.00760.x","article-title":"Distribution of neurons expressing tyrosine hydroxylase in the human cerebral cortex","volume":"211","author":"Benavides-Piccione","year":"2007","journal-title":"J Anat"},{"key":"key\n\t\t\t\t20170521001833_bib5","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/hmg\/11.8.971","article-title":"Mutations in TITF-1 are associated with benign hereditary chorea","volume":"11","author":"Breedveld","year":"2002","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170521001833_bib6","doi-asserted-by":"crossref","first-page":"17792","DOI":"10.1073\/pnas.0509032102","article-title":"Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex","volume":"102","author":"Chen","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170521001833_bib7","doi-asserted-by":"crossref","first-page":"7640","DOI":"10.1523\/JNEUROSCI.0714-06.2006","article-title":"Central roles of the roof plate in telencephalic development and holoprosencephaly","volume":"26","author":"Cheng","year":"2006","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib8","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0079-6123(06)54002-6","article-title":"Double-bouquet cells in the monkey and human cerebral cortex with special reference to areas 17 and 18","volume":"154","author":"DeFelipe","year":"2006","journal-title":"Prog Brain Res"},{"key":"key\n\t\t\t\t20170521001833_bib9","first-page":"431","article-title":"Holoprosencephaly","volume-title":"Handbook of clinical neurology","author":"DeMyer","year":"1977"},{"key":"key\n\t\t\t\t20170521001833_bib10","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/jmg.35.7.612","article-title":"Holoprosencephaly in deletions of proximal chromosome 14q","volume":"35","author":"Devriendt","year":"1998","journal-title":"J Med Genet"},{"key":"key\n\t\t\t\t20170521001833_bib11","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/cne.10654","article-title":"Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain","volume":"460","author":"Ferland","year":"2003","journal-title":"J Comp Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib12","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1399-0004.2008.00994.x","article-title":"The ups and downs of holoprosencephaly: dorsal versus ventral patterning forces","volume":"73","author":"Fernandes","year":"2008","journal-title":"Clin Genet"},{"key":"key\n\t\t\t\t20170521001833_bib13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/9780470994030.ch3","article-title":"Perspectives on the developmental origins of cortical interneuron diversity","volume":"288","author":"Fishell","year":"2007","journal-title":"Novartis Found Symp"},{"key":"key\n\t\t\t\t20170521001833_bib14","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/(SICI)1096-9861(19960122)364:4<609::AID-CNE2>3.0.CO;2-7","article-title":"Local circuit neurons in the medial prefrontal cortex (areas 24a,b,c, 25 and 32) in the monkey: II. Quantitative areal and laminar distributions","volume":"364","author":"Gabbott","year":"1996","journal-title":"J Comp Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib15","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0387-7604(99)00067-4","article-title":"Towards a greater understanding of the pathogenesis of holoprosencephaly","volume":"21","author":"Golden","year":"1999","journal-title":"Brain Dev"},{"key":"key\n\t\t\t\t20170521001833_bib16","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s00401-003-0784-0","article-title":"Neuropathological evaluation of the diencephalon, basal ganglia and upper brainstem in alobar holoprosencephaly","volume":"107","author":"Hayashi","year":"2004","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170521001833_bib17","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/cne.902930406","article-title":"Heterogeneity of chandelier neurons in monkey neocortex: corticotropin-releasing factor- and parvalbumin-immunoreactive populations","volume":"293","author":"Lewis","year":"1990","journal-title":"J Comp Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib18","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1159\/000006665","article-title":"Neurochemical and cellular specializations in the mammalian neocortex reflect phylogenetic relationships: evidence from primates, cetaceans, and artiodactyls","volume":"55","author":"Hof","year":"2000","journal-title":"Brain Behav Evol"},{"key":"key\n\t\t\t\t20170521001833_bib19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/nen.0b013e3180301c06","article-title":"Layer-specific markers as probes for neuron type identity in human neocortex and malformations of cortical development","volume":"66","author":"Hevner","year":"2007","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/cercor\/3.5.361-a","article-title":"GABAergic neurons and their role in cortical plasticity in primates","volume":"3","author":"Jones","year":"1993","journal-title":"Cereb Cortex"},{"key":"key\n\t\t\t\t20170521001833_bib21","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/s0387-7604(02)00149-3","article-title":"Dendritic overgrowth and alterations in laminar phenotypes of neocortical neurons in the newborn with semilobar holoprosencephaly","volume":"25","author":"Judas","year":"2003","journal-title":"Brain Dev"},{"key":"key\n\t\t\t\t20170521001833_bib22","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/(SICI)1097-0029(19990615)45:6<401::AID-JEMT7>3.0.CO;2-Q","article-title":"Nitrinergic neurons in the developing and adult human telencephalon: transient and permanent patterns of expression in comparison to other mammals","volume":"45","author":"Judas","year":"1999","journal-title":"Microsc Res Tech"},{"key":"key\n\t\t\t\t20170521001833_bib23","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1177\/08830738050200042001","article-title":"X-linked lissencephaly with abnormal genitalia as a tangential migration disorder causing intractable epilepsy: proposal for a new term, \u201cinterneuronopathy.\u201d","volume":"20","author":"Kato","year":"2005","journal-title":"J Child Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib24","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1023\/A:1024126110356","article-title":"Parvalbumin, somatostatin and cholecystokinin as chemical markers for specific GABAergic interneuron types in the rat frontal cortex","volume":"31","author":"Kawaguchi","year":"2002","journal-title":"J Neurocytol"},{"key":"key\n\t\t\t\t20170521001833_bib25","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.mcn.2008.05.008","article-title":"Ascl1 (Mash1) lineage cells contribute to discrete cell populations in CNS architecture","volume":"38","author":"Kim","year":"2008","journal-title":"Mol Cell Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib26","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0006-8993(94)91060-X","article-title":"Three distinct subpopulations of GABAergic neurons in rat frontal agranular cortex","volume":"649","author":"Kubota","year":"1994","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20170521001833_bib27","doi-asserted-by":"crossref","first-page":"16021","DOI":"10.1073\/pnas.0806791105","article-title":"SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons","volume":"105","author":"Kwan","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170521001833_bib28","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.conb.2008.05.006","article-title":"The determination of projection neuron identity in the developing cerebral cortex","volume":"18","author":"Leone","year":"2008","journal-title":"Curr Opin Neurobiol"},{"key":"key\n\t\t\t\t20170521001833_bib29","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/nature00779","article-title":"Origin of GABAergic neurons in the human neocortex","volume":"417","author":"Letinic","year":"2002","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170521001833_bib30","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/nrn1519","article-title":"Interneurons of the neocortical inhibitory system","volume":"5","author":"Markram","year":"2004","journal-title":"Nat Rev Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib31","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1126\/science.1067132","article-title":"Transcriptional regulation of cortical neuron migration by POU domain factors","volume":"295","author":"McEvilly","year":"2002","journal-title":"Science"},{"key":"key\n\t\t\t\t20170521001833_bib32","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1111\/j.1460-9568.2006.04630.x","article-title":"Cell and molecular mechanisms involved in the migration of cortical interneurons","volume":"23","author":"M\u00e9tin","year":"2006","journal-title":"Eur J Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib33","first-page":"1","article-title":"Genetic control of neuronal migrations in human cortical development","volume":"189","author":"Meyer","year":"2007","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"key\n\t\t\t\t20170521001833_bib34","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1007\/BF00688206","article-title":"Histopathological study of alobar holoprosencephaly. 1. Abnormal laminar architecture of the telencephalic cortex","volume":"78","author":"Mizuguchi","year":"1989","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170521001833_bib35","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/nrn2151","article-title":"Neuronal subtype specification in the cerebral cortex","volume":"8","author":"Molyneaux","year":"2007","journal-title":"Nat Rev Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib36","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1097\/nen.0b013e3180986e1b","article-title":"The morphogen signaling network in forebrain development and holoprosencephaly","volume":"66","author":"Monuki","year":"2007","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib37","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0959-437X(00)00084-8","article-title":"Genetics of ventral forebrain development and holoprosencephaly","volume":"10","author":"Muenke","year":"2000","journal-title":"Curr Opin Genet Dev"},{"key":"key\n\t\t\t\t20170521001833_bib38","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1309\/8BM44NK626997DJJ","article-title":"Cytoplasmic immunoreactivity for thyroid transcription factor-1 in hepatocellular carcinoma: a comparative immunohistochemical analysis of four commercial antibodies using a tissue array technique","volume":"21","author":"Pan","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"key\n\t\t\t\t20170521001833_bib39","article-title":"Origins of cortical GABAergic neurons in the cynomolgus monkey","author":"Petanjek","year":"2008","journal-title":"Cereb Cortex"},{"key":"key\n\t\t\t\t20170521001833_bib40","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nrn2402","article-title":"Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex","volume":"9","author":"Petilla Interneuron Nomenclature Group","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib41","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0896-6273(00)00149-5","article-title":"Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons","volume":"28","author":"Pleasure","year":"2000","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170521001833_bib42","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/cercor\/12.7.671","article-title":"Human-specific organization of primary visual cortex: alternating compartments of dense Cat-301 and calbindin immunoreactivity in layer 4A","volume":"12","author":"Preuss","year":"2002","journal-title":"Cereb Cortex"},{"key":"key\n\t\t\t\t20170521001833_bib43","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-48757-6","volume-title":"The prosencephalies: morphology, neuroradiological appearances and differential diagnosis","author":"Probst","year":"1979"},{"key":"key\n\t\t\t\t20170521001833_bib44","doi-asserted-by":"crossref","first-page":"11595","DOI":"10.1523\/JNEUROSCI.3204-07.2007","article-title":"Patterning the dorsal telencephalon: a role for sonic hedgehog?","volume":"27","author":"Rash","year":"2007","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib45","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0304-3940(92)90695-4","article-title":"Compartmentalization of NADPH-diaphorase staining in the developing human striatum","volume":"140","author":"Sajin","year":"1992","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t20170521001833_bib46","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0166-2236(94)90115-5","article-title":"Histochemical localization of nitric oxide synthase in the CNS","volume":"17","author":"Sestan","year":"1994","journal-title":"Trends Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib47","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.neuron.2005.04.019","article-title":"The cells of cajal-retzius: still a mystery one century after","volume":"46","author":"Soriano","year":"2005","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170521001833_bib48","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1023\/B:NEUR.0000029646.75645.9c","article-title":"Holoprosencephaly\u2013topologic variations in a liveborn series: a general model based upon MRI analysis","volume":"33","author":"Takahashi","year":"2004","journal-title":"J Neurocytol"},{"key":"key\n\t\t\t\t20170521001833_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-642-59425-0_1","article-title":"Calcium-binding proteins in the human developing brain","volume":"165","author":"Ulfig","year":"2002","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"key\n\t\t\t\t20170521001833_bib50","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/nrn1954","article-title":"The origin and specification of cortical interneurons","volume":"7","author":"Wonders","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib51","doi-asserted-by":"crossref","first-page":"2612","DOI":"10.1523\/JNEUROSCI.5667-03.2004","article-title":"Origins of cortical interneuron subtypes","volume":"24","author":"Xu","year":"2004","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170521001833_bib52","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/00005072-195901000-00003","article-title":"Pathoarchitectonic studies of cerebral malformations. III. Arhinencephalies(holotelencephalies)","volume":"18","author":"Yakovlev","year":"1959","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170521001833_bib53","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/cne.20714","article-title":"Contributions of cortical subventricular zone to the development of the human cerebral cortex","volume":"491","author":"Zecevic","year":"2005","journal-title":"J Comp Neurol"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cercor\/article-pdf\/19\/9\/2196\/17302656\/bhp009.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T22:52:02Z","timestamp":1503442322000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cercor\/article-lookup\/doi\/10.1093\/cercor\/bhp009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,20]]},"references-count":53,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2009,2,20]]},"published-print":{"date-parts":[[2009,9]]}},"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhp009","relation":{},"ISSN":["1460-2199","1047-3211"],"issn-type":[{"value":"1460-2199","type":"electronic"},{"value":"1047-3211","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2,20]]}}}