{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:03:29Z","timestamp":1791068609934,"version":"4.1.0"},"reference-count":66,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1093\/cercor\/bhq023","type":"journal-article","created":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T23:44:52Z","timestamp":1267487092000},"page":"2749-2759","source":"Crossref","is-referenced-by-count":150,"title":["Abnormal Activation of the Primary Somatosensory Cortex in Spasmodic Dysphonia: An fMRI Study"],"prefix":"10.1093","volume":"20","author":[{"given":"Kristina","family":"Simonyan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christy L.","family":"Ludlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,3,1]]},"reference":[{"key":"key\n\t\t\t\t20170520230711_bib1","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1044\/1092-4388(2006\/081)","article-title":"Alterations in CNS activity induced by botulinum toxin treatment in spasmodic dysphonia: an H215O PET study","volume":"49","author":"Ali","year":"2006","journal-title":"J Speech Lang Hear Res"},{"issue":"Pt 4","key":"key\n\t\t\t\t20170520230711_bib2","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1093\/brain\/106.4.981","article-title":"Stereotaxic thalamotomy in 55 cases of dystonia","volume":"106","author":"Andrew","year":"1983","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib3","first-page":"1449","article-title":"Preceptual structures and distributed motor control","volume-title":"Handbook of physiology. Motor control","author":"Arbib","year":"1981"},{"key":"key\n\t\t\t\t20170520230711_bib4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0021-9924(00)00039-3","article-title":"Identification of symptoms for spasmodic dysphonia and vocal tremor: a comparison of expert and nonexpert judges","volume":"34","author":"Barkmeier","year":"2001","journal-title":"J Commun Disord"},{"key":"key\n\t\t\t\t20170520230711_bib5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/(SICI)1097-0193(1999)7:2<106::AID-HBM4>3.0.CO;2-O","article-title":"Event-related fMRI of tasks involving brief motion","volume":"7","author":"Birn","year":"1999","journal-title":"Hum Brain Mapp"},{"key":"key\n\t\t\t\t20170520230711_bib6","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1212\/WNL.51.3.819","article-title":"Putamen volume in idiopathic focal dystonia","volume":"51","author":"Black","year":"1998","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib7","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/000348948509400111","article-title":"Symptom improvement of spastic dysphonia in response to phonatory tasks","volume":"94","author":"Bloch","year":"1985","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"key\n\t\t\t\t20170520230711_bib8","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/ana.20108","article-title":"Basal ganglia activity remains elevated after movement in focal hand dystonia","volume":"55","author":"Blood","year":"2004","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170520230711_bib9","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/mds.10416","article-title":"Abnormal cortical sensory activation in dystonia: an fMRI study","volume":"18","author":"Butterworth","year":"2003","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170520230711_bib10","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0306-4522(97)00672-6","article-title":"Cerebellar circuitry is activated during convulsive episodes in the tottering (tg\/tg) mutant mouse","volume":"85","author":"Campbell","year":"1998","journal-title":"Neuroscience"},{"key":"key\n\t\t\t\t20170520230711_bib11","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1227\/00006123-199503000-00009","article-title":"Outcome after stereotactic thalamotomy for dystonia and hemiballismus","volume":"36","author":"Cardoso","year":"1995","journal-title":"Neurosurgery"},{"issue":"Pt 4","key":"key\n\t\t\t\t20170520230711_bib12","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1093\/brain\/120.4.571","article-title":"Botulinum toxin does not reverse the cortical dysfunction associated with writer's cramp. A PET study","volume":"120","author":"Ceballos-Baumann","year":"1997","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib13","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1212\/WNL.49.4.1054","article-title":"Impaired inhibition in writer's cramp during voluntary muscle activation","volume":"49","author":"Chen","year":"1997","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib14","first-page":"423","article-title":"20-year followup study of the neurosurgical treatment of dystonia musculorum deformans","volume":"14","author":"Cooper","year":"1976","journal-title":"Adv Neurol"},{"key":"key\n\t\t\t\t20170520230711_bib15","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/cbmr.1996.0014","article-title":"AFNI: software for analysis and visualization of functional magnetic resonance neuroimages","volume":"29","author":"Cox","year":"1996","journal-title":"Comput Biomed Res"},{"key":"key\n\t\t\t\t20170520230711_bib16","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.clineuro.2007.09.020","article-title":"Changed patterns of cerebral activation related to clinically normal hand movement in cervical dystonia","volume":"110","author":"de Vries","year":"2008","journal-title":"Clin Neurol Neurosurg"},{"key":"key\n\t\t\t\t20170520230711_bib17","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1093\/brain\/awl355","article-title":"Do primary adult-onset focal dystonias share aetiological factors?","volume":"130","author":"Defazio","year":"2007","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib18","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1212\/01.WNL.0000094240.93745.83","article-title":"\u201cMotor circuit\u201d gray matter changes in idiopathic cervical dystonia","volume":"61","author":"Draganski","year":"2003","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib19","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/brain\/awh665","article-title":"Silent event-related fMRI reveals deficient motor and enhanced somatosensory activation in orofacial dystonia","volume":"129","author":"Dresel","year":"2006","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib20","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/S0892-1997(01)00038-8","article-title":"Acoustic measures of symptoms in abductor spasmodic dysphonia","volume":"15","author":"Edgar","year":"2001","journal-title":"J Voice"},{"key":"key\n\t\t\t\t20170520230711_bib21","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.neuroimage.2004.12.034","article-title":"A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data","volume":"25","author":"Eickhoff","year":"2005","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170520230711_bib22","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1044\/1058-0360(2003\/087)","article-title":"Effects of voicing and syntactic complexity on sign expression in adductor spasmodic dysphonia","volume":"12","author":"Erickson","year":"2003","journal-title":"Am J Speech Lang Pathol"},{"key":"key\n\t\t\t\t20170520230711_bib23","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0304-3940(97)13370-5","article-title":"Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation","volume":"222","author":"Filipovic","year":"1997","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t20170520230711_bib24","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/mds.870030410","article-title":"Degenerative cerebellar ataxia and focal dystonia","volume":"3","author":"Fletcher","year":"1988","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170520230711_bib25","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1002\/mrm.1910330508","article-title":"Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold","volume":"33","author":"Forman","year":"1995","journal-title":"Magn Reson Med"},{"key":"key\n\t\t\t\t20170520230711_bib26","doi-asserted-by":"crossref","first-page":"977","DOI":"10.3171\/JNS-07\/11\/0977","article-title":"Thalamic deep brain stimulation for writer's cramp","volume":"107","author":"Fukaya","year":"2007","journal-title":"J Neurosurg"},{"key":"key\n\t\t\t\t20170520230711_bib27","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1600-0404.1996.tb07049.x","article-title":"Basal ganglia and thalamo-cortical hypermetabolism in patients with spasmodic torticollis","volume":"94","author":"Galardi","year":"1996","journal-title":"Acta Neurol Scand"},{"key":"key\n\t\t\t\t20170520230711_bib28","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/382805a0","article-title":"Two different areas within the primary motor cortex of man","volume":"382","author":"Geyer","year":"1996","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170520230711_bib29","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1006\/nimg.1999.0440","article-title":"Areas 3a, 3b, and 1 of human primary somatosensory cortex","volume":"10","author":"Geyer","year":"1999","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170520230711_bib30","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1006\/nimg.2000.0548","article-title":"Areas 3a, 3b, and 1 of human primary somatosensory cortex. Part 2. Spatial normalization to standard anatomical space","volume":"11","author":"Geyer","year":"2000","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170520230711_bib31","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1006\/nimg.2001.0858","article-title":"Human somatosensory area 2: observer-independent cytoarchitectonic mapping, interindividual variability, and population map","volume":"14","author":"Grefkes","year":"2001","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170520230711_bib32","first-page":"171","article-title":"Long term results of stereotaxic surgery for infantile dystonia and dyskinesia","volume":"19","author":"Gros","year":"1976","journal-title":"Neurochirurgia (Stuttg)"},{"key":"key\n\t\t\t\t20170520230711_bib33","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.bandl.2005.06.001","article-title":"Neural modeling and imaging of the cortical interactions underlying syllable production","volume":"96","author":"Guenther","year":"2006","journal-title":"Brain Lang"},{"key":"key\n\t\t\t\t20170520230711_bib34","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/ana.410380203","article-title":"Is dystonia a sensory disorder?","volume":"38","author":"Hallett","year":"1995","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170520230711_bib35","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1212\/01.wnl.0000184478.59063.db","article-title":"\"Silent event-related\" fMRI reveals reduced sensorimotor activation in laryngeal dystonia","volume":"65","author":"Haslinger","year":"2005","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib36","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1212\/WNL.55.5.673","article-title":"The metabolic topography of essential blepharospasm: a focal dystonia with general implications","volume":"55","author":"Hutchinson","year":"2000","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib37","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1212\/WNL.53.1.96","article-title":"Deficient activation of the motor cortical network in patients with writer's cramp","volume":"53","author":"Ibanez","year":"1999","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib38","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1212\/01.wnl.0000246112.19504.61","article-title":"A new twist on the anatomy of dystonia: the basal ganglia and the cerebellum?","volume":"67","author":"Jinnah","year":"2006","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib39","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0149-7634(01)00068-9","article-title":"Neural pathways underlying vocal control","volume":"26","author":"Jurgens","year":"2002","journal-title":"Neurosci Biobehav Rev"},{"key":"key\n\t\t\t\t20170520230711_bib40","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ana.410380206","article-title":"Tonic vibration reflex and muscle afferent block in writer's cramp","volume":"38","author":"Kaji","year":"1995","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170520230711_bib41","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.jvoice.2006.05.001","article-title":"Reliability of clinician-based (GRBAS and CAPE-V) and patient-based (V-RQOL and IPVI) documentation of voice disorders","volume":"21","author":"Karnell","year":"2007","journal-title":"J Voice"},{"key":"key\n\t\t\t\t20170520230711_bib42","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1136\/jnnp.33.4.513","article-title":"Neurosurgery in cerebral palsy","volume":"33","author":"Laitinen","year":"1970","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170520230711_bib43","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1212\/01.wnl.0000244484.60489.50","article-title":"Predominant dystonia with marked cerebellar atrophy: a rare phenotype in familial dystonia","volume":"67","author":"Le Ber","year":"2006","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170520230711_bib44","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/mds.870090502","article-title":"Movement disorders following lesions of the thalamus or subthalamic region","volume":"9","author":"Lee","year":"1994","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170520230711_bib45","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1136\/jnnp.65.5.767","article-title":"Pallidal activity during dystonia: somatosensory reorganisation and changes with severity","volume":"65","author":"Lenz","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170520230711_bib46","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.neuroimage.2003.10.019","article-title":"Regional cerebral blood flow correlates of the severity of writer's cramp symptoms","volume":"21","author":"Lerner","year":"2004","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170520230711_bib47","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.otohns.2008.05.624","article-title":"Research priorities in spasmodic dysphonia","volume":"139","author":"Ludlow","year":"2008","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20170520230711_bib48","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1097\/00005537-199604000-00017","article-title":"Laryngeal muscle activity during speech breaks in adductor spasmodic dysphonia","volume":"106","author":"Nash","year":"1996","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20170520230711_bib49","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1093\/brain\/awn168","article-title":"The basal ganglia and cerebellum interact in the expression of dystonic movement","volume":"131","author":"Neychev","year":"2008","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib50","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/mds.870130321","article-title":"Cerebral and cerebellar activation in correlation to the action-induced dystonia in writer's cramp","volume":"13","author":"Odergren","year":"1998","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170520230711_bib51","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/brain\/awf083","article-title":"Abnormal cortical mechanisms of voluntary muscle relaxation in patients with writer's cramp: an fMRI study","volume":"125","author":"Oga","year":"2002","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib52","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: the Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"key\n\t\t\t\t20170520230711_bib53","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1093\/brain\/awl181","article-title":"The basal ganglia are hyperactive during the discrimination of tactile stimuli in writer's cramp","volume":"129","author":"Peller","year":"2006","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib54","doi-asserted-by":"crossref","first-page":"7825","DOI":"10.1523\/JNEUROSCI.22-17-07825.2002","article-title":"Abnormal cerebellar signaling induces dystonia in mice","volume":"22","author":"Pizoli","year":"2002","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170520230711_bib55","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s004150170263","article-title":"Cerebral activation patterns in patients with writer's cramp: a functional magnetic resonance imaging study","volume":"248","author":"Preibisch","year":"2001","journal-title":"J Neurol"},{"key":"key\n\t\t\t\t20170520230711_bib56","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1006\/nimg.2000.0615","article-title":"Brain cortical activation during guitar-induced hand dystonia studied by functional MRI","volume":"12","author":"Pujol","year":"2000","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170520230711_bib57","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1136\/jnnp.59.5.493","article-title":"Changes in the balance between motor cortical excitation and inhibition in focal, task specific dystonia","volume":"59","author":"Ridding","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"Pt 2","key":"key\n\t\t\t\t20170520230711_bib58","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1113\/jphysiol.1995.sp020898","article-title":"The effect of voluntary contraction on cortico-cortical inhibition in human motor cortex","volume":"487","author":"Ridding","year":"1995","journal-title":"J Physiol"},{"key":"key\n\t\t\t\t20170520230711_bib59","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S0892-1997(00)80008-9","article-title":"Adductor spasmodic dysphonia and muscular tension dysphonia: acoustic analysis of sustained phonation and reading","volume":"14","author":"Sapienza","year":"2000","journal-title":"J Voice"},{"key":"key\n\t\t\t\t20170520230711_bib60","first-page":"S159","article-title":"Gray matter abnormalities in spasmodic dysphonia","volume-title":"Movement disorders","author":"Simonyan","year":"2008"},{"key":"key\n\t\t\t\t20170520230711_bib61","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/lary.20677","article-title":"Brainstem pathology in spasmodic dysphonia","volume":"120","author":"Simonyan","year":"2010","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20170520230711_bib62","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/brain\/awm303","article-title":"Focal white matter changes in spasmodic dysphonia: a combined diffusion tensor imaging and neuropathological study","volume":"131","author":"Simonyan","year":"2008","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib63","volume-title":"Co-planer stereotaxic atlas of the human brain","author":"Talairach","year":"1988"},{"key":"key\n\t\t\t\t20170520230711_bib64","first-page":"615","article-title":"Thalamotomy in generalized dystonia","volume":"50","author":"Tasker","year":"1988","journal-title":"Adv Neurol"},{"issue":"Pt 3","key":"key\n\t\t\t\t20170520230711_bib65","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/brain\/113.3.691","article-title":"Abnormal vibration-induced cerebral blood flow responses in idiopathic dystonia","volume":"113","author":"Tempel","year":"1990","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170520230711_bib66","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1006\/nimg.2000.0672","article-title":"Differential contributions of motor cortex, basal ganglia, and cerebellum to speech motor control: effects of syllable repetition rate evaluated by fMRI","volume":"13","author":"Wildgruber","year":"2001","journal-title":"Neuroimage"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cercor\/article-pdf\/20\/11\/2749\/17302969\/bhq023.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T02:24:20Z","timestamp":1635042260000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cercor\/article-lookup\/doi\/10.1093\/cercor\/bhq023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,1]]},"references-count":66,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2010,3,1]]},"published-print":{"date-parts":[[2010,11]]}},"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhq023","relation":{},"ISSN":["1460-2199","1047-3211"],"issn-type":[{"value":"1460-2199","type":"electronic"},{"value":"1047-3211","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3,1]]}}}