{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:42:25Z","timestamp":1790365345163,"version":"4.1.0"},"reference-count":89,"publisher":"Oxford University Press (OUP)","funder":[{"name":"National Institute of Health","award":["R01 NSO41489"],"award-info":[{"award-number":["R01 NSO41489"]}]},{"name":"National Institute of Health","award":["5R01DA023999-07"],"award-info":[{"award-number":["5R01DA023999-07"]}]},{"name":"Advanced Bioscience Resources"},{"name":"Joint MRC\/Welcome Trust","award":["099175\/Z\/12\/Z"],"award-info":[{"award-number":["099175\/Z\/12\/Z"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cereb. Cortex"],"DOI":"10.1093\/cercor\/bhw194","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T01:14:32Z","timestamp":1473210872000},"source":"Crossref","is-referenced-by-count":27,"title":["Oxygen Levels Regulate the Development of Human Cortical Radial Glia Cells"],"prefix":"10.1093","author":[{"given":"J. Alberto","family":"Ortega","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carissa L.","family":"Sirois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fani","family":"Memi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Glidden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada","family":"Zecevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,9,6]]},"reference":[{"key":"2016090618094288000_bhw194v1.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02761-6"},{"key":"2016090618094288000_bhw194v1.2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820150007001"},{"key":"2016090618094288000_bhw194v1.3","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1523\/JNEUROSCI.21-04-01302.2001","article-title":"Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury","volume":"21","author":"Back","year":"2001","journal-title":"J Neurosci"},{"key":"2016090618094288000_bhw194v1.4","first-page":"288","article-title":"The role of hypoxia in mental development and in the treatment of mental disorders: a review","volume":"4","author":"Basovich","year":"2010","journal-title":"Biosci Trends"},{"key":"2016090618094288000_bhw194v1.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.09.032"},{"key":"2016090618094288000_bhw194v1.6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1305411110"},{"key":"2016090618094288000_bhw194v1.7","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-008-1336-6"},{"key":"2016090618094288000_bhw194v1.8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1474-9728.2003.00066.x"},{"key":"2016090618094288000_bhw194v1.9","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.1.35"},{"key":"2016090618094288000_bhw194v1.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2011.01258.x"},{"key":"2016090618094288000_bhw194v1.11","doi-asserted-by":"publisher","DOI":"10.1017\/S1462399405009622"},{"key":"2016090618094288000_bhw194v1.12","doi-asserted-by":"publisher","DOI":"10.4161\/org.4.2.5852"},{"key":"2016090618094288000_bhw194v1.13","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/13.6.599"},{"key":"2016090618094288000_bhw194v1.14","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-010-0566-3"},{"key":"2016090618094288000_bhw194v1.15","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-011-0723-5"},{"key":"2016090618094288000_bhw194v1.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(01)00306-1"},{"key":"2016090618094288000_bhw194v1.17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0501283102"},{"key":"2016090618094288000_bhw194v1.18","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2855"},{"key":"2016090618094288000_bhw194v1.19","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1561"},{"key":"2016090618094288000_bhw194v1.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.10.045"},{"key":"2016090618094288000_bhw194v1.21","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1242\/dev.125.12.2315","article-title":"The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice","volume":"125","author":"Grove","year":"1998","journal-title":"Development"},{"key":"2016090618094288000_bhw194v1.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2005.09.010"},{"key":"2016090618094288000_bhw194v1.23","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5297-05.2006"},{"key":"2016090618094288000_bhw194v1.24","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20259"},{"key":"2016090618094288000_bhw194v1.25","doi-asserted-by":"crossref","first-page":"401323","DOI":"10.1155\/2010\/401323","article-title":"Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review","volume":"2010","author":"Hutter","year":"2010","journal-title":"Int J Pediatr"},{"key":"2016090618094288000_bhw194v1.26","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21690"},{"key":"2016090618094288000_bhw194v1.27","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhq245"},{"key":"2016090618094288000_bhw194v1.28","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20134"},{"key":"2016090618094288000_bhw194v1.29","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.4.1172-1183.2002"},{"key":"2016090618094288000_bhw194v1.30","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1534"},{"key":"2016090618094288000_bhw194v1.31","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3183"},{"key":"2016090618094288000_bhw194v1.32","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5286-12.2013"},{"key":"2016090618094288000_bhw194v1.33","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80159-2"},{"key":"2016090618094288000_bhw194v1.34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2004.02.016"},{"key":"2016090618094288000_bhw194v1.35","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0177(20010201)220:2<175::AID-DVDY1101>3.0.CO;2-F"},{"key":"2016090618094288000_bhw194v1.36","doi-asserted-by":"publisher","DOI":"10.1038\/nature00779"},{"key":"2016090618094288000_bhw194v1.37","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2011.10.004"},{"key":"2016090618094288000_bhw194v1.38","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1300.007"},{"key":"2016090618094288000_bhw194v1.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2012.05.010"},{"key":"2016090618094288000_bhw194v1.40","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600277"},{"key":"2016090618094288000_bhw194v1.41","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000110047.43905.01"},{"key":"2016090618094288000_bhw194v1.42","doi-asserted-by":"publisher","DOI":"10.1038\/nature13973"},{"key":"2016090618094288000_bhw194v1.43","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1162"},{"key":"2016090618094288000_bhw194v1.44","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4445-12.2013"},{"key":"2016090618094288000_bhw194v1.45","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3155"},{"key":"2016090618094288000_bhw194v1.46","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbr069"},{"key":"2016090618094288000_bhw194v1.47","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh610"},{"key":"2016090618094288000_bhw194v1.48","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2102"},{"key":"2016090618094288000_bhw194v1.49","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0111-07.2007"},{"key":"2016090618094288000_bhw194v1.50","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20775"},{"key":"2016090618094288000_bhw194v1.51","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2010.07.007"},{"key":"2016090618094288000_bhw194v1.52","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5404-10.2011"},{"key":"2016090618094288000_bhw194v1.53","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2013.00254"},{"key":"2016090618094288000_bhw194v1.54","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21812"},{"key":"2016090618094288000_bhw194v1.55","first-page":"424","article-title":"Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes","volume":"35","author":"Pistollato","year":"2007","journal-title":"MCN"},{"key":"2016090618094288000_bhw194v1.56","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.09.004"},{"key":"2016090618094288000_bhw194v1.57","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.01.049"},{"key":"2016090618094288000_bhw194v1.58","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00325-13"},{"key":"2016090618094288000_bhw194v1.59","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.11.026"},{"key":"2016090618094288000_bhw194v1.60","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/cercor\/bhu183","article-title":"The role of sonic hedgehog in the specification of human cortical progenitors in vitro","volume":"26","author":"Radonjic","year":"2014","journal-title":"Cereb Cortex"},{"key":"2016090618094288000_bhw194v1.61","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.2.119"},{"key":"2016090618094288000_bhw194v1.62","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/13.10.1072"},{"key":"2016090618094288000_bhw194v1.63","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1501733"},{"key":"2016090618094288000_bhw194v1.64","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.02.002"},{"key":"2016090618094288000_bhw194v1.65","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000123906.17746.00"},{"key":"2016090618094288000_bhw194v1.66","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-183X.2003.00037.x"},{"key":"2016090618094288000_bhw194v1.67","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0008575"},{"key":"2016090618094288000_bhw194v1.68","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2015.115"},{"key":"2016090618094288000_bhw194v1.69","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2354"},{"key":"2016090618094288000_bhw194v1.70","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0125com"},{"key":"2016090618094288000_bhw194v1.71","doi-asserted-by":"crossref","first-page":"7377","DOI":"10.1523\/JNEUROSCI.20-19-07377.2000","article-title":"Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen","volume":"20","author":"Studer","year":"2000","journal-title":"J Neurosci"},{"key":"2016090618094288000_bhw194v1.72","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2004.10.019"},{"key":"2016090618094288000_bhw194v1.73","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200004000-00018"},{"key":"2016090618094288000_bhw194v1.74","doi-asserted-by":"publisher","DOI":"10.1080\/01688639708403840"},{"key":"2016090618094288000_bhw194v1.75","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-3806(00)00135-8"},{"key":"2016090618094288000_bhw194v1.76","first-page":"17","article-title":"Chronic hypoxia induces the activation of the Wnt\/beta-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1DeltaE9 transgenic mice in vivo","volume":"8","author":"Varela-Nallar","year":"2014","journal-title":"Front Cel Neurosci"},{"key":"2016090618094288000_bhw194v1.77","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3041-11.2011"},{"key":"2016090618094288000_bhw194v1.78","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22533"},{"key":"2016090618094288000_bhw194v1.79","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1987.01800190080012"},{"key":"2016090618094288000_bhw194v1.80","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.08.015"},{"key":"2016090618094288000_bhw194v1.81","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00485.2010"},{"key":"2016090618094288000_bhw194v1.82","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh618"},{"key":"2016090618094288000_bhw194v1.83","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.09.021"},{"key":"2016090618094288000_bhw194v1.84","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2009.08.001"},{"key":"2016090618094288000_bhw194v1.85","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5249-10.2011"},{"key":"2016090618094288000_bhw194v1.86","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.04.052"},{"key":"2016090618094288000_bhw194v1.87","doi-asserted-by":"publisher","DOI":"10.1002\/cne.20714"},{"key":"2016090618094288000_bhw194v1.88","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.20812"},{"key":"2016090618094288000_bhw194v1.89","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnmol.2011.00005","article-title":"Oxygen, a key factor regulating cell behavior during neurogenesis and cerebral diseases","volume":"4","author":"Zhang","year":"2011","journal-title":"Front Mol Neurosci"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cercor\/article-pdf\/27\/7\/3736\/17948874\/bhw194.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T21:09:51Z","timestamp":1657228191000},"score":1,"resource":{"primary":{"URL":"http:\/\/cercor.oxfordjournals.org\/cgi\/doi\/10.1093\/cercor\/bhw194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,6]]},"references-count":89,"alternative-id":["10.1093\/cercor\/bhw194"],"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhw194","relation":{},"ISSN":["1047-3211","1460-2199"],"issn-type":[{"value":"1047-3211","type":"print"},{"value":"1460-2199","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,6]]}}}