{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:33:31Z","timestamp":1793172811337,"version":"4.5.0"},"reference-count":69,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T00:00:00Z","timestamp":1506556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003977","name":"Israel Science Foundation","doi-asserted-by":"publisher","award":["1047\/12"],"award-info":[{"award-number":["1047\/12"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Teva Pharmaceuticals National Network of Excellence in Neuroscience"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,12,1]]},"DOI":"10.1093\/cercor\/bhx250","type":"journal-article","created":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T17:33:13Z","timestamp":1504719193000},"page":"5739-5754","source":"Crossref","is-referenced-by-count":99,"title":["Dysregulation of Cortical Neuron DNA Methylation Profile in Autism Spectrum Disorder"],"prefix":"10.1093","volume":"27","author":[{"given":"Stefano","family":"Nardone","sequence":"first","affiliation":[{"name":"Bar Ilan University Faculty of Medicine, Hanrietta Sold 8, Safed 13215, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dev Sharan","family":"Sams","sequence":"additional","affiliation":[{"name":"Bar Ilan University Faculty of Medicine, Hanrietta Sold 8, Safed 13215, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Zito","sequence":"additional","affiliation":[{"name":"Department of Twin Research and Genetic Epidemiology, King\u2019s College London, London SE1 7EH, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Reuveni","sequence":"additional","affiliation":[{"name":"Bar Ilan University Faculty of Medicine, Hanrietta Sold 8, Safed 13215, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Elliott","sequence":"additional","affiliation":[{"name":"Bar Ilan University Faculty of Medicine, Hanrietta Sold 8, Safed 13215, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,9,28]]},"reference":[{"key":"key\n\t\t\t\t2019012505163720600_bhx250C1","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders: DSM-5TM","author":"American Psychiatric Association","year":"2013","edition":"5th ed."},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C2","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/bioinformatics\/btu049","article-title":"Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays","volume":"30","author":"Aryee","year":"2014","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C3","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.bbr.2016.05.033","article-title":"Sustained lentiviral-mediated overexpression of microRNA124a in the dentate gyrus exacerbates anxiety- and autism-like behaviors associated with neonatal isolation in rats","volume":"311","author":"Bahi","year":"2016","journal-title":"Behav Brain Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1093\/bioinformatics\/btt019","article-title":"CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data","volume":"29","author":"Bindea","year":"2013","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ymeth.2014.10.036","article-title":"Probe Lasso: a novel method to rope in differentially methylated regions with 450K DNA methylation data","volume":"72","author":"Butcher","year":"2015","journal-title":"Methods"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00787-006-0563-2","article-title":"Epilepsy in autism spectrum disorders","volume":"16","author":"Canitano","year":"2007","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C7","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nature09582","article-title":"Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes","volume":"468","author":"Chao","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C8","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4161\/epi.23470","article-title":"Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray","volume":"8","author":"Chen","year":"2013","journal-title":"Epigenetics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C9","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nn.2294","article-title":"miR-124 regulates adult neurogenesis in the SVZ stem cell niche","volume":"12","author":"Cheng","year":"2009","journal-title":"Nat Neurosci"},{"issue":"7","key":"key\n\t\t\t\t2019012505163720600_bhx250C10","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nrn.2016.41","article-title":"The landscape of DNA methylation amid a perfect storm of autism aetiologies","volume":"17","author":"Ciernia","year":"2016","journal-title":"Nat Rev Neurosci"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/nature13772","article-title":"Synaptic, transcriptional and chromatin genes disrupted in autism","volume":"515","author":"De Rubeis","year":"2014","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C12","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/mp.2009.118","article-title":"Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism","volume":"16","author":"Delahanty","year":"2011","journal-title":"Mol Psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s10803-008-0646-7","article-title":"GABAA receptor downregulation in brains of subjects with autism","volume":"39","author":"Fatemi","year":"2009","journal-title":"J Autism Dev Disord"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C14","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1038\/nm.3717","article-title":"Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia","volume":"20","author":"Gascon","year":"2014","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C15","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/ng.3039","article-title":"Most genetic risk for autism resides with common variation","volume":"46","author":"Gaugler","year":"2014","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C16","first-page":"329","article-title":"The interaction between the immune system and epigenetics in the etiology of autism spectrum disorders involvement of maternal immune activation in autism","volume":"10","author":"Gesundheit","year":"2016","journal-title":"Front Neurosci"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C17","doi-asserted-by":"crossref","first-page":"5748","DOI":"10.1038\/ncomms6748","article-title":"Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism","volume":"5","author":"Gupta","year":"2014","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/neuro.09.031.2009","article-title":"The human brain in numbers: a linearly scaled-up primate brain","volume":"3","author":"Herculano-Houzel","year":"2009","journal-title":"Front Hum Neurosci"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C19","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1126\/science.aad8373","article-title":"Complement and microglia mediate early synapse loss in Alzheimer mouse models","volume":"352","author":"Hong","year":"2016","journal-title":"Science"},{"issue":"2","key":"key\n\t\t\t\t2019012505163720600_bhx250C20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1023\/A:1010715619091","article-title":"Suppressed gabaergic inhibition as a common factor in suspected etiologies of autism [1]","volume":"31","author":"Hussman","year":"2001","journal-title":"J Autism Dev Disord"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C21","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/nature13908","article-title":"The contribution of de novo coding mutations to autism spectrum disorder","volume":"515","author":"Iossifov","year":"2014","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C22","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/nn.4181","article-title":"Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex","volume":"19","author":"Jaffe","year":"2016","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C23","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/gb-2014-15-2-r31","article-title":"Accounting for cellular heterogeneity is critical in epigenome-wide association studies","volume":"15","author":"Jaffe","year":"2014","journal-title":"Genome Biol"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C24","doi-asserted-by":"crossref","first-page":"766","DOI":"10.15252\/embr.201438840","article-title":"Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy","volume":"15","author":"Kahle","year":"2014","journal-title":"EMBO Rep"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C25","doi-asserted-by":"crossref","first-page":"e755","DOI":"10.1038\/cddis.2013.278","article-title":"Early methyl donor deficiency may induce persistent brain defects by reducing Stat3 signaling targeted by miR-124","volume":"4","author":"Kerek","year":"2013","journal-title":"Cell Death Dis"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C26","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neuron.2012.12.023","article-title":"Microglia: new roles for the synaptic stripper","volume":"77","author":"Kettenmann","year":"2013","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C27","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1093\/nar\/gkv1304","article-title":"Substantial DNA methylation differences between two major neuronal subtypes in human brain","volume":"44","author":"Kozlenkov","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C28","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1093\/bioinformatics\/btr167","article-title":"Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications","volume":"27","author":"Krueger","year":"2011","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C29","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1080\/15592294.2015.1114202","article-title":"Maternal immune activation induces GAD1 and GAD2 promoter remodeling in the offspring prefrontal cortex","volume":"10","author":"Labouesse","year":"2015","journal-title":"Epigenetics"},{"issue":"8","key":"key\n\t\t\t\t2019012505163720600_bhx250C30","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/mp.2013.114","article-title":"Common DNA methylation alterations in multiple brain regions in autism","volume":"19","author":"Ladd-Acosta","year":"2013","journal-title":"Mol Psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C31","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1003118","article-title":"Software for computing and annotating genomic ranges","volume":"9","author":"Lawrence","year":"2013","journal-title":"PLoS Comput Biol"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C33","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.bbi.2014.09.001","article-title":"Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders","volume":"44","author":"Lee","year":"2014","journal-title":"Brain Behav Immun"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C34","doi-asserted-by":"crossref","first-page":"D1047","DOI":"10.1093\/nar\/gkr1182","article-title":"GWASdb: a database for human genetic variants identified by genome-wide association studies","volume":"40","author":"Li","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C35","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1126\/science.1237905","article-title":"Global epigenomic reconfiguration during mammalian brain development","volume":"341","author":"Lister","year":"2013","journal-title":"Science"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C36","doi-asserted-by":"crossref","DOI":"10.3791\/914","article-title":"Neuronal nuclei isolation from human postmortem brain tissue","author":"Matevossian","year":"2008","journal-title":"J Vis Exp"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C37","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/nbt.1630","article-title":"GREAT improves functional interpretation of cis-regulatory regions","volume":"28","author":"McLean","year":"2010","journal-title":"Nat Biotechnol"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C38","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.neuron.2015.05.018","article-title":"Epigenomic signatures of neuronal diversity in the mammalian brain","volume":"86","author":"Mo","year":"2015","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C39","doi-asserted-by":"crossref","first-page":"R94","DOI":"10.1186\/gb-2013-14-8-r94","article-title":"Measuring cell-type specific differential methylation in human brain tissue","volume":"14","author":"Monta\u00f1o","year":"2013","journal-title":"Genome Biol"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C40","first-page":"46","article-title":"Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex. Mol","volume":"6","author":"Mor","year":"2015","journal-title":"Autism"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C41","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/bioinformatics\/btt684","article-title":"ChAMP: 450k chip analysis methylation pipeline","volume":"30","author":"Morris","year":"2014","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C42","doi-asserted-by":"crossref","first-page":"e433","DOI":"10.1038\/tp.2014.70","article-title":"DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways","volume":"4","author":"Nardone","year":"2014","journal-title":"Transl Psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C43","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.brainres.2010.09.021","article-title":"Reduced GABAA receptors and benzodiazepine binding sites in the posterior cingulate cortex and fusiform gyrus in autism","volume":"1380","author":"Oblak","year":"2011","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C44","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1038\/nn.2207","article-title":"Functional organization of the transcriptome in human brain","volume":"11","author":"Oldham","year":"2009","journal-title":"Nat Neurosci"},{"issue":"7633","key":"key\n\t\t\t\t2019012505163720600_bhx250C45","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nature20612","article-title":"Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism","volume":"540","author":"Parikshak","year":"2016","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C46","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/nature09230","article-title":"Epigenetics as a unifying principle in the aetiology of complex traits and diseases","volume":"465","author":"Petronis","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C47","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1093\/bioinformatics\/btq033","article-title":"BEDTools: a flexible suite of utilities for comparing genomic features","volume":"26","author":"Quinlan","year":"2010","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C48","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/nrg3000","article-title":"Epigenome-wide association studies for common human diseases","volume":"12","author":"Rakyan","year":"2011","journal-title":"Nat Rev Genet"},{"issue":"3","key":"key\n\t\t\t\t2019012505163720600_bhx250C49","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.biopsych.2016.08.010","article-title":"Genome-wide DNA methylation changes in a mouse model of infection-mediated neurodevelopmental disorders","volume":"81","author":"Richetto","year":"2016","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C50","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nature13595","article-title":"Biological insights from 108 schizophrenia-associated genetic loci","volume":"511","author":"Ripke","year":"2014","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C51","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C52","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.cub.2015.11.019","article-title":"Reduced GABAergic action in the autistic brain","volume":"26","author":"Robertson","year":"2016","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C53","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nature16549","article-title":"Schizophrenia risk from complex variation of complement component 4","volume":"530","author":"Sekar","year":"2016","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C54","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C55","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1001\/archgenpsychiatry.2011.151","article-title":"Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons","volume":"69","author":"Shulha","year":"2012","journal-title":"Arch Gen Psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C56","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1101\/gr.180273.114","article-title":"Methylomic trajectories across human fetal brain development","volume":"25","author":"Spiers","year":"2015","journal-title":"Genome Res"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C57","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.cell.2016.10.031","article-title":"Histone acetylome-wide association study of autism spectrum disorder","volume":"167","author":"Sun","year":"2016","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C58","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3389\/fncel.2015.00193","article-title":"An updated role of microRNA-124 in central nervous system disorders: a review","volume":"9","author":"Sun","year":"2015","journal-title":"Front Cell Neurosci"},{"issue":"2","key":"key\n\t\t\t\t2019012505163720600_bhx250C59","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nn.4216","article-title":"Adult mouse cortical cell taxonomy revealed by single cell transcriptomics","volume":"19","author":"Tasic","year":"2016","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C60","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3389\/fpsyt.2014.00053","article-title":"Gene \u00d7 Environment interactions in autism spectrum disorders: role of epigenetic mechanisms","volume":"5","author":"Tordjman","year":"2014","journal-title":"Front psychiatry"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C61","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nature10110","article-title":"Transcriptomic analysis of autistic brain reveals convergent molecular pathology","volume":"474","author":"Voineagu","year":"2011","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C62","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/onc.2012.598","article-title":"Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1","volume":"33","author":"Wang","year":"2014","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C63","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1126\/science.1190485","article-title":"Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes","volume":"329","author":"Wu","year":"2010","journal-title":"Science"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C64","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1038\/nn.4373","article-title":"Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder","volume":"19","author":"Wu","year":"2016","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C65","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.cell.2013.04.022","article-title":"Epigenomic analysis of multilineage differentiation of human embryonic stem cells","volume":"153","author":"Xie","year":"2013","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C66","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuron.2012.02.003","article-title":"EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation","volume":"73","author":"Yang","year":"2012","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C67","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nature08139","article-title":"MicroRNA-mediated switching of chromatin-remodelling complexes in neural development","volume":"460","author":"Yoo","year":"2009","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C68","first-page":"e349","article-title":"Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum","volume-title":"Transl Psychiatry","author":"Zhubi","year":"2014"},{"key":"key\n\t\t\t\t2019012505163720600_bhx250C69","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s12031-012-9880-8","article-title":"Aberrant expression of long noncoding RNAs in autistic brain","volume":"49","author":"Ziats","year":"2013","journal-title":"J Mol Neurosci"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cercor\/article-pdf\/27\/12\/5739\/27598338\/bhx250.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T01:34:58Z","timestamp":1570066498000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cercor\/article\/27\/12\/5739\/4259743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,28]]},"references-count":69,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,9,28]]},"published-print":{"date-parts":[[2017,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhx250","relation":{},"ISSN":["1047-3211","1460-2199"],"issn-type":[{"value":"1047-3211","type":"print"},{"value":"1460-2199","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,12]]},"published":{"date-parts":[[2017,9,28]]}}}