{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:11:11Z","timestamp":1789229471458,"version":"build-2803163510"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T00:00:00Z","timestamp":1517184000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100002426","name":"Fondazione Telethon","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002426","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fondation Lejeune"},{"DOI":"10.13039\/100013104","name":"SISSA","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100013104","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,1]]},"DOI":"10.1093\/cercor\/bhy007","type":"journal-article","created":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T20:07:37Z","timestamp":1515355657000},"page":"1006-1019","source":"Crossref","is-referenced-by-count":33,"title":["<i>Foxg1<\/i>Overexpression in Neocortical Pyramids Stimulates Dendrite Elongation Via<i>Hes1<\/i>and pCreb1 Upregulation"],"prefix":"10.1093","volume":"29","author":[{"given":"Simone","family":"Chiola","sequence":"first","affiliation":[{"name":"Lab of Cerebral Cortex Development, Neuroscience Area, SISSA, via Bonomea Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihn Duc","family":"Do","sequence":"additional","affiliation":[{"name":"Lab of Cerebral Cortex Development, Neuroscience Area, SISSA, via Bonomea Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Centrone","sequence":"additional","affiliation":[{"name":"Lab of Cerebral Cortex Development, Neuroscience Area, SISSA, via Bonomea Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonello","family":"Mallamaci","sequence":"additional","affiliation":[{"name":"Lab of Cerebral Cortex Development, Neuroscience Area, SISSA, via Bonomea Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,1,28]]},"reference":[{"key":"key\n\t\t\t\t2019021310101852700_bhy007C1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fncel.2012.00061","article-title":"Molecular mechanisms of dendrite morphogenesis","volume":"6","author":"Arikkath","year":"2012","journal-title":"Front Cell Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1146\/annurev.neuro.31.060407.125536","article-title":"Establishment of axon-dendrite polarity in developing neurons","volume":"32","author":"Barnes","year":"2009","journal-title":"Annu Rev Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C3","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.braindev.2013.06.008","article-title":"14q12 duplication including FOXG1: is there a common age-dependent epileptic phenotype?","volume":"36","author":"Bertossi","year":"2014","journal-title":"Brain Dev"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C4","doi-asserted-by":"crossref","first-page":"11697","DOI":"10.1523\/JNEUROSCI.1113-11.2011","article-title":"Nuclear factor B-dependent neurite remodeling is mediated by notchathway","volume":"31","author":"Bonini","year":"2011","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C5","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1002\/stem.443","article-title":"Emx2 and Foxg1 inhibit gliogenesis and promote neuronogenesis","volume":"28","author":"Brancaccio","year":"2010","journal-title":"Stem Cells Dayt Ohio"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C6","doi-asserted-by":"crossref","first-page":"20558","DOI":"10.1073\/pnas.0710156104","article-title":"Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus","volume":"104","author":"Breunig","year":"2007","journal-title":"Proc Natl Acad Sci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/alzrt134","article-title":"Increased expression of the homologue of enhancer-of-split 1 protects neurons from beta amyloid neurotoxicity and hints at an alternative role for transforming growth factor beta1 as a neuroprotector","volume":"4","author":"Chac\u00f3n","year":"2012","journal-title":"Alzheimers Res Ther"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.mcn.2004.08.012","article-title":"Regulation of cortical dendrite development by Rap1 signaling","volume":"28","author":"Chen","year":"2005","journal-title":"Mol Cell Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C9","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.neuron.2011.09.018","article-title":"Transcriptional regulation of neuronal polarity and morphogenesis in the mammalian brain","volume":"72","author":"de la Torre-Ubieta","year":"2011","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C10","doi-asserted-by":"crossref","first-page":"152","DOI":"10.2174\/1566523211313020009","article-title":"Promotion of cortico-cerebral precursors expansion by artificial pri-miRNAs targeted against the Emx2 locus","volume":"13","author":"Diodato","year":"2013","journal-title":"Curr Gene Ther"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C11","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1002\/stem.56","article-title":"cAMP response element binding protein is required for mouse neural progenitor cell survival and expansion","volume":"27","author":"Dworkin","year":"2009","journal-title":"Stem Cells"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C12","doi-asserted-by":"crossref","first-page":"39311","DOI":"10.1038\/srep39311","article-title":"RNA activation of haploinsufficient Foxg1 gene in murine neocortex","volume":"6","author":"Fimiani","year":"2016","journal-title":"Sci Rep."},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C13","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0896-6273(03)00841-9","article-title":"A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis","volume":"41","author":"Gaudilli\u00e8re","year":"2004","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C14","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1111\/j.1528-1167.2012.03656.x","article-title":"Epilepsy in Rett syndrome, and CDKL5- and FOXG1-gene-related encephalopathies","volume":"53","author":"Guerrini","year":"2012","journal-title":"Epilepsia"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C15","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.cellsig.2014.11.034","article-title":"The Notch intracellular domain represses CRE-dependent transcription","volume":"27","author":"Hallaq","year":"2015","journal-title":"Cell Signal"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C16","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1126\/science.1090674","article-title":"Foxg1 suppresses early cortical cell fate","volume":"303","author":"Hanashima","year":"2004","journal-title":"Science"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C17","doi-asserted-by":"crossref","first-page":"11103","DOI":"10.1523\/JNEUROSCI.1066-07.2007","article-title":"The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes","volume":"27","author":"Hanashima","year":"2007","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C18","first-page":"201","article-title":"Over expression of FGF7 enhances cell proliferation but fails to cause pathology in corneal epithelium of Kerapr-rtTA\/FGF7 bitransgenic mice","volume":"11","author":"Hayashi","year":"2005","journal-title":"Mol Vis"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C19","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/nature07198","article-title":"Neurogenin 2 controls cortical neuron migration through regulation of Rnd2","volume":"455","author":"Heng","year":"2008","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C20","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1126\/science.1074560","article-title":"Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop","volume":"298","author":"Hirata","year":"2002","journal-title":"Science"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C21","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1186\/1471-2105-12-230","article-title":"NeurphologyJ: an automatic neuronal morphology quantification method and its application in pharmacological discovery","volume":"12","author":"Ho","year":"2011","journal-title":"BMC Bioinform"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C22","doi-asserted-by":"crossref","first-page":"4312","DOI":"10.1523\/JNEUROSCI.0126-09.2009","article-title":"A SnoN-Ccd1 pathway promotes axonal morphogenesis in the mammalian brain","volume":"29","author":"Ikeuchi","year":"2009","journal-title":"J Neurosci Off J Soc Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C23","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.pediatrneurol.2005.08.005","article-title":"Epilepsy syndromes in infancy","volume":"34","author":"Korff","year":"2006","journal-title":"Pediatr Neurol"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C24","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.mcn.2012.03.005","article-title":"The dendritic tree and brain disorders","volume":"50","author":"Kulkarni","year":"2012","journal-title":"Mol Cell Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C25","first-page":"538","article-title":"Activity-independent effects of CREB on neuronal survival and differentiation during mouse cerebral cortex development","volume":"28","author":"Landeira","year":"2018","journal-title":"Cereb Cortex"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C26","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1242\/dev.039800","article-title":"The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice","volume":"137","author":"Manuel","year":"2010","journal-title":"Development"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C27","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.cell.2015.06.034","article-title":"FOXG1-dependent dysregulation of GABA\/glutamate neuron differentiation in autism spectrum disorders","volume":"162","author":"Mariani","year":"2015","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C28","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ydbio.2005.04.005","article-title":"Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis","volume":"283","author":"Martynoga","year":"2005","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C29","doi-asserted-by":"crossref","first-page":"D142","DOI":"10.1093\/nar\/gkt997","article-title":"JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles","volume":"42","author":"Mathelier","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C30","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.neuron.2012.04.025","article-title":"Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate","volume":"74","author":"Miyoshi","year":"2012","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C31","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1523\/JNEUROSCI.4804-04.2005","article-title":"Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium","volume":"25","author":"Muzio","year":"2005","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C32","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1093\/emboj\/18.8.2196","article-title":"Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation","volume":"18","author":"Ohtsuka","year":"1999","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C33","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1242\/dev.101378","article-title":"Growth differentiation factor 5 is a key physiological regulator of dendrite growth during development","volume":"140","author":"Osorio","year":"2013","journal-title":"Development"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C34","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/ejhg.2015.216","article-title":"Imbalance of excitatory\/inhibitory synaptic protein expression in iPSC-derived neurons from FOXG1(+\/\u2212) patients and in foxg1(+\/\u2212) mice","volume":"24","author":"Patriarchi","year":"2016","journal-title":"Eur J Hum Genet EJHG"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C35","doi-asserted-by":"crossref","first-page":"9127","DOI":"10.1523\/JNEUROSCI.6167-09.2010","article-title":"NFIA controls telencephalic progenitor cell differentiation through repression of the notch effector Hes1","volume":"30","author":"Piper","year":"2010","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C36","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.pediatrneurol.2014.01.022","article-title":"Epilepsy in patients with duplications of chromosome 14 harboring FOXG1","volume":"50","author":"Pontrelli","year":"2014","journal-title":"Pediatr Neurol"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C37","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.1242\/dev.087676","article-title":"Cell-intrinsic drivers of dendrite morphogenesis","volume":"140","author":"Puram","year":"2013","journal-title":"Development"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C38","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0896-6273(02)00737-7","article-title":"Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription","volume":"34","author":"Redmond","year":"2002","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C39","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/71104","article-title":"Nuclear Notch1 signaling and the regulation of dendritic development","volume":"3","author":"Redmond","year":"2000","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.2010.07080.x","article-title":"CREB: a multifaceted regulator of neuronal plasticity and protection: CREB in synaptic plasticity and cell survival","volume":"116","author":"Sakamoto","year":"2011","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C41","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1091\/mbc.e04-05-0438","article-title":"NGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch","volume":"16","author":"Salama-Cohen","year":"2005","journal-title":"Mol Biol Cell"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C42","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1126\/science.286.5440.741","article-title":"Contact-dependent inhibition of cortical neurite growth mediated by notch signaling","volume":"286","author":"Sestan","year":"1999","journal-title":"Science"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C43","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1093\/cercor\/bhm209","article-title":"Foxg1 haploinsufficiency reduces the population of cortical intermediate progenitor cells: effect of increased p21 expression","volume":"18","author":"Siegenthaler","year":"2008","journal-title":"Cereb Cortex"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C44","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/nrn2286","article-title":"Pyramidal neurons: dendritic structure and synaptic integration","volume":"9","author":"Spruston","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C45","doi-asserted-by":"crossref","first-page":"10348","DOI":"10.1523\/JNEUROSCI.1258-13.2013","article-title":"Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways","volume":"33","author":"Staahl","year":"2013","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C46","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1212\/WNL.0b013e3182194bbf","article-title":"West syndrome associated with 14q12 duplications harboring FOXG1","volume":"76","author":"Striano","year":"2011","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C47","doi-asserted-by":"crossref","first-page":"5150","DOI":"10.1016\/S0021-9258(17)37668-8","article-title":"Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements","volume":"269","author":"Takebayashi","year":"1994","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C48","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1002\/ajmg.a.34224","article-title":"West syndrome associated with mosaic duplication of FOXG1 in a patient with maternal uniparental disomy of chromosome 14","volume":"155A","author":"Tohyama","year":"2011","journal-title":"Am J Med Genet A"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C49","doi-asserted-by":"crossref","first-page":"13259","DOI":"10.1523\/JNEUROSCI.2334-14.2014","article-title":"The timing of upper-layer neurogenesis is conferred by sequential derepression and negative feedback from deep-layer neurons","volume":"34","author":"Toma","year":"2014","journal-title":"J Neurosci Off J Soc Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C50","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/82868","article-title":"Neurotrophins are required for nerve growth during development","volume":"4","author":"Tucker","year":"2001","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C51","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.neuron.2012.01.019","article-title":"Chemical genetic identification of NDR1\/2 kinase substrates AAK1 and Rabin8 uncovers their roles in dendrite arborization and spine development","volume":"73","author":"Ultanir","year":"2012","journal-title":"Neuron"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C52","doi-asserted-by":"crossref","first-page":"264","DOI":"10.55782\/ane-2008-1695","article-title":"Molecular basis of dendritic arborization","volume":"68","author":"Urbanska","year":"2008","journal-title":"Acta Neurobiol Exp (Warsz)"},{"key":"key\n\t\t\t\t2019021310101852700_bhy007C53","doi-asserted-by":"crossref","first-page":"12950","DOI":"10.1074\/jbc.M508691200","article-title":"Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3\u03b2","volume":"281","author":"Valerio","year":"2006","journal-title":"J Biol Chem"}],"container-title":["Cerebral Cortex"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cercor\/article-pdf\/29\/3\/1006\/27768663\/bhy007.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T12:52:34Z","timestamp":1751201554000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cercor\/article\/29\/3\/1006\/4828055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,28]]},"references-count":53,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,1,28]]},"published-print":{"date-parts":[[2019,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cercor\/bhy007","relation":{},"ISSN":["1047-3211","1460-2199"],"issn-type":[{"value":"1047-3211","type":"print"},{"value":"1460-2199","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,3]]},"published":{"date-parts":[[2018,1,28]]}}}