{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:19:21Z","timestamp":1790083161894,"version":"4.0.1"},"reference-count":105,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DP1OD003312"],"award-info":[{"award-number":["DP1OD003312"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG030311"],"award-info":[{"award-number":["R01 AG030311"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\u201cSuperagers\u201d are older adults who, despite their advanced age, maintain youthful memory. Previous morphometry studies revealed multiple default mode network (DMN) and salience network (SN) regions whose cortical thickness is greater in superagers and correlates with memory performance. In this study, we examined the intrinsic functional connectivity within DMN and SN in 41 young (24.5\u2009\u00b1\u20093.6 years old) and 40 older adults (66.9\u2009\u00b1\u20095.5 years old). Superaging was defined as youthful performance on a memory recall task, the California Verbal Learning Test (CVLT). Participants underwent a resting-state functional magnetic resonance imaging (fMRI) scan and performed a separate visual\u2013verbal recognition memory task. As predicted, within both DMN and SN, superagers had stronger connectivity compared with typical older adults and similar connectivity compared with young adults. Superagers also performed similarly to young adults and better than typical older adults on the recognition task, demonstrating youthful episodic memory that generalized across memory tasks. Stronger connectivity within each network independently predicted better performance on both the CVLT and recognition task in older adults. Variation in intrinsic connectivity explained unique variance in memory performance, above and beyond youthful neuroanatomy. These results extend our understanding of the neural basis of superaging as a model of successful aging.<\/jats:p>","DOI":"10.1093\/cercor\/bhz071","type":"journal-article","created":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T20:23:44Z","timestamp":1552940624000},"page":"72-84","source":"Crossref","is-referenced-by-count":70,"title":["Stronger Functional Connectivity in the Default Mode and Salience Networks Is Associated With Youthful Memory in Superaging"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7520-074X","authenticated-orcid":false,"given":"Jiahe","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Psychology, Northeastern University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M","family":"Andreano","sequence":"first","affiliation":[{"name":"Psychiatric Neuroimaging Division, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"},{"name":"Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradford C","family":"Dickerson","sequence":"first","affiliation":[{"name":"Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"},{"name":"Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA"},{"name":"Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Touroutoglou","sequence":"first","affiliation":[{"name":"Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"},{"name":"Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA"},{"name":"Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa Feldman","family":"Barrett","sequence":"first","affiliation":[{"name":"Department of Psychology, Northeastern University, Boston, MA, USA"},{"name":"Psychiatric Neuroimaging Division, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA"},{"name":"Athinoula A. 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