{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:59:58Z","timestamp":1789552798689,"version":"build-2803163510"},"reference-count":68,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T00:00:00Z","timestamp":1568246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Shenzhen Double Chain","award":["2018[256]"],"award-info":[{"award-number":["2018[256]"]}]},{"name":"Shenzhen Basic Research","award":["JCYJ20170818110022721"],"award-info":[{"award-number":["JCYJ20170818110022721"]}]},{"name":"Shenzhen Basic Research","award":["JCYJ20170412164259361"],"award-info":[{"award-number":["JCYJ20170412164259361"]}]},{"name":"Shenzhen Basic Research","award":["JCYJ20170412164413575"],"award-info":[{"award-number":["JCYJ20170412164413575"]}]},{"name":"Shenzhen Basic Research","award":["JCYJ20170818110103216"],"award-info":[{"award-number":["JCYJ20170818110103216"]}]},{"name":"Guangdong Key Basic Research","award":["2018B030332001"],"award-info":[{"award-number":["2018B030332001"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31700951"],"award-info":[{"award-number":["31700951"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangdong Pearl River Talents Plan Innovative and Entrepreneurial Team","award":["2016ZT06S220"],"award-info":[{"award-number":["2016ZT06S220"]}]},{"name":"Shenzhen Peacock Team Plan","award":["KQTD2015033016104926"],"award-info":[{"award-number":["KQTD2015033016104926"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Men and women process language differently, but how the brain functions to support this difference is poorly understood. A few studies reported sex influences on brain activation for language, whereas others failed to detect the difference at the functional level. Recent advances of brain network analysis have shown great promise in picking up brain connectivity differences between sexes, leading us to hypothesize that the functional connections among distinct brain regions for language may differ in males and females. To test this hypothesis, we scanned 58 participants\u2019 brain activities (28 males and 30 females) in a semantic decision task using functional magnetic resonance imaging. We found marked sex differences in dynamic interactions among language regions, as well as in functional segregation and integration of brain networks during language processing. The brain network differences were further supported by a machine learning analysis that accurately discriminated males from females using the multivariate patterns of functional connectivity. The sex-specific functional brain connectivity may constitute an essential neural basis for the long-held notion that men and women process language in different ways. Our finding also provides important implications for sex differences in the prevalence of language disorders, such as dyslexia and stuttering.<\/jats:p>","DOI":"10.1093\/cercor\/bhz184","type":"journal-article","created":{"date-parts":[[2019,8,11]],"date-time":"2019-08-11T04:46:41Z","timestamp":1565498801000},"page":"1528-1537","source":"Crossref","is-referenced-by-count":53,"title":["Sex Differences in Functional Brain Networks for Language"],"prefix":"10.1093","volume":"30","author":[{"given":"Min","family":"Xu","sequence":"first","affiliation":[{"name":"Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen 518060, China"},{"name":"Center for Language and Brain, Shenzhen Institute of Neuroscience, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuling","family":"Liang","sequence":"first","affiliation":[{"name":"Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen 518060, China"},{"name":"Center for Language and Brain, Shenzhen Institute of Neuroscience, Shenzhen 518060, China"},{"name":"School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Ou","sequence":"first","affiliation":[{"name":"Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen 518060, China"},{"name":"Center for Language and Brain, Shenzhen Institute of Neuroscience, Shenzhen 518060, China"},{"name":"School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Li","sequence":"first","affiliation":[{"name":"Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen 518060, China"},{"name":"Center for Language and Brain, Shenzhen Institute of Neuroscience, Shenzhen 518060, China"},{"name":"School of Psychology, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-jia","family":"Luo","sequence":"first","affiliation":[{"name":"Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen 518060, China"},{"name":"Center for Language and Brain, Shenzhen Institute of Neuroscience, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Hai","family":"Tan","sequence":"first","affiliation":[{"name":"Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen 518060, China"},{"name":"Center for Language and Brain, Shenzhen Institute of Neuroscience, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,9,12]]},"reference":[{"key":"2020040606552961200_ref1","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuron.2005.07.023","article-title":"Dissociable controlled retrieval and generalized selection mechanisms in ventrolateral prefrontal cortex","volume":"47","author":"Badre","year":"2005","journal-title":"Neuron."},{"key":"2020040606552961200_ref2","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/S0093-934X(02)00549-7","article-title":"Sex differences in semantic language processing: a functional MRI study","volume":"84","author":"Baxter","year":"2003","journal-title":"Brain Lang."},{"key":"2020040606552961200_ref3","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1093\/cercor\/bhp055","article-title":"Where is the semantic system? 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