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We further evaluated the predictive value of baseline depression, anxiety, and olfaction scores on depression and anxiety at follow-up. At baseline, olfactory function and affective state were assessed in 107 participants (53 patients with mTBI; 54 healthy controls). At follow-up, data were collected on 71 participants (32 patients and 39 controls). Both at baseline and follow-up, patients with mTBI showed more signs of parosmia, depression, and anxiety compared with controls. However, patients did not, neither at baseline nor follow-up, show quantitative olfactory impairment. Moreover, although baseline scores of depression and anxiety helped predict the development of symptoms of depression and anxiety at follow-up, adding parosmia scores to the prediction model significantly increased the amount of explained variances. Clinicians should implement affective and olfactory evaluation to predict patients\u2019 affective outcome.<\/jats:p>","DOI":"10.1093\/chemse\/bjaa037","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T19:15:26Z","timestamp":1591038926000},"page":"483-490","source":"Crossref","is-referenced-by-count":15,"title":["Early Parosmia Signs and Affective States Predict Depression and Anxiety Symptoms 6 Months After a Mild Traumatic Brain Injury"],"prefix":"10.1093","volume":"45","author":[{"given":"Fanny","family":"Lecuyer Giguere","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Centre de Recherche Interdisciplinaire en R\u00e9adaptation du Montr\u00e9al M\u00e9tropolitain, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Research Center, CIUSSS\u2013NIM, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1357-5116","authenticated-orcid":false,"given":"Benoit","family":"Jobin","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Research Center, CIUSSS\u2013NIM, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00eblle","family":"Robert","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Sherbrooke, Sherbrooke, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurianne","family":"Bastien","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Research Center, CIUSSS\u2013NIM, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Fran\u00e7ois","family":"Gigu\u00e8re","sequence":"first","affiliation":[{"name":"Research Center, CIUSSS\u2013NIM, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"De Beaumont","sequence":"first","affiliation":[{"name":"Research Center, CIUSSS\u2013NIM, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Department of Surgery, University of Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaine","family":"de Guise","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Centre de Recherche Interdisciplinaire en R\u00e9adaptation du Montr\u00e9al M\u00e9tropolitain, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Research Institute, McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Frasnelli","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Research Center, CIUSSS\u2013NIM, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Department of Anatomy, University of Qu\u00e9bec in Trois-Rivi\u00e8res, Trois-Rivi\u00e8res, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,6,9]]},"reference":[{"issue":"7","key":"2020070705342348800_CIT0001","doi-asserted-by":"crossref","first-page":"e102627","DOI":"10.1371\/journal.pone.0102627","article-title":"Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury","volume":"9","author":"Almeida-Suhett","year":"2014","journal-title":"PLoS One"},{"key":"2020070705342348800_CIT0002","first-page":"21","article-title":"Natural history of post-concussive signs and symptoms. 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