{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:53:45Z","timestamp":1790776425707,"version":"4.1.0"},"reference-count":59,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100011074","name":"University of Lyon","doi-asserted-by":"publisher","award":["ANR-16-IDEX-0005"],"award-info":[{"award-number":["ANR-16-IDEX-0005"]}],"id":[{"id":"10.13039\/501100011074","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fondation Fyssen Paris","award":["173867"],"award-info":[{"award-number":["173867"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Although olfactory disorders (OD) are among the most significant symptoms of COVID-19, recovery time from COVID-19-related OD and their consequences on the quality of life remain poorly documented. We investigated the characteristics and behavioral consequences of COVID-19-related OD using a large-scale study involving 3111 French respondents (78% women) to an online questionnaire over a period of 9 months covering different epidemic waves (from 8 April 2020 to 13 January 2021). In the patients who subjectively recovered from COVID-19-related OD (N = 609), recovery occurred on average after 16 days and most of the time within 1 month (\u201cnormal\u201d recovery range); 49 subjectively recovered in 1\u20132.5 months, and several cases took up to 6.5 months. Among the patients with ongoing OD (N = 2502), 974 were outside the \u201cnormal\u201d recovery range (persistent OD) and reported OD for 1\u201310 months. Developing a persistent OD was more likely with increasing age and in women and was more often associated with parosmia and phantosmia. The deleterious impact of COVID-19-related OD on the quality of life was significantly aggravated by OD duration and was more pronounced in women. Because persistent OD is not infrequent after COVID-19, has deleterious consequences on the quality of life, and receives few solutions from the health practitioners, it would be beneficial to implement screening and treatment programs to minimize the long-term behavioral consequences of COVID-19-related OD.<\/jats:p>","DOI":"10.1093\/chemse\/bjab028","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T11:32:28Z","timestamp":1622806348000},"source":"Crossref","is-referenced-by-count":31,"title":["Recovery From COVID-19-Related Olfactory Disorders and Quality of Life: Insights From an Observational Online Study"],"prefix":"10.1093","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5572-0361","authenticated-orcid":false,"given":"Camille","family":"Ferdenzi","sequence":"first","affiliation":[{"name":"Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1 , CH Le Vinatier, B\u00e2t. 462 Neurocampus, 95 boulevard Pinel, 69675 Bron Cedex , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1650-8004","authenticated-orcid":false,"given":"Christophe","family":"Bousquet","sequence":"additional","affiliation":[{"name":"Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1 , CH Le Vinatier, B\u00e2t. 462 Neurocampus, 95 boulevard Pinel, 69675 Bron Cedex , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Emmanuel","family":"Aguera","sequence":"additional","affiliation":[{"name":"Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1 , CH Le Vinatier, B\u00e2t. 462 Neurocampus, 95 boulevard Pinel, 69675 Bron Cedex , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgane","family":"Dantec","sequence":"additional","affiliation":[{"name":"Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, 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Claude Bernard Lyon 1 , CH Le Vinatier, B\u00e2t. 462 Neurocampus, 95 boulevard Pinel, 69675 Bron Cedex , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lien","family":"Kassan","sequence":"additional","affiliation":[{"name":"Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1 , CH Le Vinatier, B\u00e2t. 462 Neurocampus, 95 boulevard Pinel, 69675 Bron Cedex , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4258-5847","authenticated-orcid":false,"given":"Marylou","family":"Mantel","sequence":"additional","affiliation":[{"name":"Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1 , CH Le Vinatier, B\u00e2t. 462 Neurocampus, 95 boulevard Pinel, 69675 Bron Cedex , 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