{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T06:12:56Z","timestamp":1783836776612,"version":"3.55.0"},"reference-count":65,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Sensonics International Research Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Electrogustometry (EGM) is a practical way to test taste. It is typically performed using unipolar electrodes, with the anode on the tongue and the cathode on the hand, forearm, or neck. This results in electric current passing through nontaste tissues and adds a level of impracticality to its clinical application. We compared, using a repeated measures counterbalanced design, anodal thresholds from a unipolar electrode to those of a unique bipolar electrode in which the anode and cathode are contiguously located. Both sides of the anterior tongue were assessed in 70 subjects, as were the effects of age and sex. Nonparametric analyses were performed. The median threshold of the bipolar electrode\u2019s central disk (2.49 \u00b5A) did not differ from that of the unipolar electrode (2.96 \u00b5A) (P = 0.84). On average, older persons exhibited higher thresholds. No significant sex or tongue side effects were evident. Interestingly, when the annular (donut-shaped) bipolar electrode served as the anode, the threshold was higher than that of the other electrodes (5.19 \u00b5A; Ps &amp;lt; 0.001). This conceivably reflected lessened summation of activity among adjacent afferents and partial sampling of tongue regions with fewer taste buds. Correlations among all EGM thresholds were nominally higher for women than for men, ranging from 0.83 to 0.85 for women and 0.54 to 0.67 for men; all Ps &amp;lt; 0.001. This study validates the use of a bipolar electrode for assessing taste function, averting movement of current through nontaste-related tissues and making such testing safer and more practical.<\/jats:p>","DOI":"10.1093\/chemse\/bjad009","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T12:06:06Z","timestamp":1679659566000},"source":"Crossref","is-referenced-by-count":3,"title":["Electrogustometry: validation of bipolar electrode stimulation"],"prefix":"10.1093","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8185-3886","authenticated-orcid":false,"given":"Toshi","family":"Matsuda","sequence":"first","affiliation":[{"name":"Research Division, Sensonics International , Haddon Heights, NJ 08035 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5919-0986","authenticated-orcid":false,"given":"Pavana","family":"Mysore Ganesh","sequence":"additional","affiliation":[{"name":"Research Division, Sensonics International , Haddon Heights, NJ 08035 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0399-8449","authenticated-orcid":false,"given":"Robert","family":"Brown","sequence":"additional","affiliation":[{"name":"Research Division, Sensonics International , Haddon Heights, NJ 08035 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4459-1493","authenticated-orcid":false,"given":"Vince","family":"Grosso","sequence":"additional","affiliation":[{"name":"Research Division, Sensonics International , Haddon Heights, NJ 08035 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8378-2623","authenticated-orcid":false,"given":"Richard L","family":"Doty","sequence":"additional","affiliation":[{"name":"Smell and Taste Center, Department of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA 19104 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,3,24]]},"reference":[{"issue":"1","key":"2023041310574500400_","first-page":"1","article-title":"Electrogustometric investigations during manned space flight","volume":"54","author":"Baranski","year":"1983","journal-title":"Aviat Space Environ Med"},{"issue":"5","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"488","DOI":"10.3109\/00016489.2010.535850","article-title":"Evaluation of electrogustometry and the filter paper disc method for taste assessment","volume":"131","author":"Berling","year":"2011","journal-title":"Acta Otolaryngol"},{"issue":"5","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/j.1600-0722.2008.00556.x","article-title":"Taste deficits after middle ear surgery for otosclerosis: taste somatosensory interactions","volume":"116","author":"Berteretche","year":"2008","journal-title":"Eur J Oral Sci"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/odi.12630","article-title":"Taste function assessed by electrogustometry in burning mouth syndrome: a case-control study","volume":"23","author":"Braud","year":"2017","journal-title":"Oral Dis"},{"key":"2023041310574500400_","first-page":"1260","article-title":"L\u2019establissement de la sensation du gout dit electrique en foncion de la duree d\u2019excitation","volume":"122","author":"Bujas","year":"1936","journal-title":"C R Soc Biol"},{"issue":"4","key":"2023041310574500400_","first-page":"353","article-title":"Neural effects of electrical taste stimuli","volume":"3","author":"Bujas","year":"1979","journal-title":"Sens Processes"},{"issue":"6","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1017\/S0022215100063969","article-title":"Taste and the chorda tympani","volume":"79","author":"Bull","year":"1965","journal-title":"J Laryngol Otol"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.wjorl.2021.02.001","article-title":"Objective screening for olfactory and gustatory dysfunction during the COVID-19 pandemic: a prospective study in healthcare workers using self-administered testing","volume":"8","author":"Cao","year":"2022","journal-title":"World J Otorhinolaryngol Head Neck Surg"},{"issue":"3","key":"2023041310574500400_","first-page":"90","article-title":"Electrogustometry in oral submucous fibrosis. A study in 50 cases","volume":"3","author":"Chaturvedi","year":"1992","journal-title":"Indian J Dent Res"},{"issue":"1","key":"2023041310574500400_","first-page":"27","article-title":"Cardiac pacemaker inhibition by transcutaneous electrical nerve stimulation","volume":"71","author":"Chen","year":"1990","journal-title":"Arch Phys Med Rehabil"},{"key":"2023041310574500400_","first-page":"385","article-title":"Taste and smell in aging.","volume-title":"Clinical Neurology of Aging","author":"Doty","year":"2011"},{"key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-444-63855-7.00001-0","article-title":"Epidemiology of smell and taste dysfunction","volume":"164","author":"Doty","year":"2019","journal-title":"Handb Clin Neurol"},{"key":"2023041310574500400_","volume-title":"Electrogustometer SI-03: Operation and Administration Manual","author":"Doty","year":"2020"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0031-9384(00)00416-9","article-title":"NaCl thresholds: relationship to anterior tongue locus, area of stimulation, and number of fungiform papillae","volume":"72","author":"Doty","year":"2001","journal-title":"Physiol Behav"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.physbeh.2015.12.014","article-title":"Influences of age, tongue region, and chorda tympani nerve sectioning on signal detection measures of lingual taste sensitivity","volume":"155","author":"Doty","year":"2016","journal-title":"Physiol Behav"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"864","DOI":"10.3758\/s13428-020-01463-8","article-title":"Validation of the Waterless Empirical Taste Test (WETT\u00ae)","volume":"53","author":"Doty","year":"2021","journal-title":"Behav Res Methods"},{"issue":"6","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/00016487009123391","article-title":"Electrogustometry. Spatial threshold variations","volume":"69","author":"Fons","year":"1970","journal-title":"Acta Otolaryngol"},{"issue":"3 pt 1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1177\/000348947608500306","article-title":"Electrically evoked taste threshold","volume":"85","author":"F\u00f8ns","year":"1976","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"10","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1017\/S0022215100071206","article-title":"Electrogustometry II. I. The spread of the stimulating current","volume":"83","author":"Fons","year":"1969","journal-title":"J Laryngol Otol"},{"key":"2023041310574500400_","first-page":"503","article-title":"Electrogustometry: a simple way to test taste.","volume-title":"Smell and Taste in Health and Disease","author":"Frank","year":"1991"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1136\/jnnp.50.1.12","article-title":"Evoked taste thresholds in a normal population and the application of electrogustometry to trigeminal nerve disease","volume":"50","author":"Grant","year":"1987","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"9","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1017\/S0022215100079469","article-title":"Significance of taste and electrogustometry in assessing the prognosis of Bell\u2019s (idiopathic) facial palsy","volume":"88","author":"Groves","year":"1974","journal-title":"J Laryngol Otol"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/BF00235926","article-title":"The cathodal OFF response of electric taste in rats","volume":"60","author":"Herness","year":"1985","journal-title":"Exp Brain Res"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1085\/jgp.86.1.59","article-title":"Neurophysiological and biophysical evidence on the mechanism of electric taste","volume":"86","author":"Herness","year":"1985","journal-title":"J Gen Physiol"},{"issue":"4","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000245237","article-title":"Changes in taste sensitivity with advancing age","volume":"11","author":"Hughes","year":"1969","journal-title":"Gerontol Clin (Basel)"},{"issue":"7","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/01.mlg.0000224509.61099.29","article-title":"Contact endoscopic comparison of morphology of human fungiform papillae of healthy subjects and patients with transected chorda tympani nerve","volume":"116","author":"Just","year":"2006","journal-title":"Laryngoscope"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1600-0714.2009.00824.x","article-title":"Oral pain perception and taste in burning mouth syndrome","volume":"39","author":"Just","year":"2010","journal-title":"J Oral Pathol Med"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1085\/jgp.78.3.259","article-title":"Taste transduction mechanism: similar effects of various modifications of gustatory receptors on neural responses to chemical and electrical stimulation in the frog","volume":"78","author":"Kashiwayanagi","year":"1981","journal-title":"J Gen Physiol"},{"issue":"8","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.3950\/jibiinkoka.98.1291","article-title":"[Electric gustatory threshold in diabetics and its clinical significance]","volume":"98","author":"Kawaguchi","year":"1995","journal-title":"Nihon Jibiinkoka Gakkai Kaiho"},{"issue":"5","key":"2023041310574500400_","first-page":"ZC101","article-title":"Comparison of taste threshold in smokers and non-smokers using electrogustometry and fungiform papillae count: a case control study","volume":"10","author":"Khan","year":"2016","journal-title":"J Clin Diagn Res"},{"issue":"4","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3109\/00016485809134758","article-title":"Electro-gustometry. A method for clinical taste examination","volume":"49","author":"Krarup","year":"1958","journal-title":"Acta Otolaryngol"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1212\/WNL.9.1.53","article-title":"Electrogustometric examinations in cerebellopontine tumors and on taste pathways","volume":"9","author":"Krarup","year":"1959","journal-title":"Neurology"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0031-9384(98)00307-2","article-title":"Gustatory changes associated with the menstrual cycle","volume":"66","author":"Kuga","year":"1999","journal-title":"Physiol Behav"},{"issue":"Suppl","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1080\/00016480260046544","article-title":"Changes in gustatory sense during pregnancy","author":"Kuga","year":"2002","journal-title":"Acta Otolaryngol"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1068\/p100035","article-title":"An examination of intertrial interval and gender influences on sucrose detection thresholds established by a modified staircase procedure","volume":"10","author":"Kunka","year":"1981","journal-title":"Perception"},{"issue":"11","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"e013246","DOI":"10.1136\/bmjopen-2016-013246","article-title":"Prevalence and risk factors of taste and smell impairment in a nationwide representative sample of the US population: a cross-sectional study","volume":"6","author":"Liu","year":"2016","journal-title":"BMJ Open"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1085\/jgp.57.1.1","article-title":"Peripheral interactions among single papilla inputs to gustatory nerve fibers","volume":"57","author":"Miller","year":"1971","journal-title":"J Gen Physiol"},{"issue":"5","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0031-9384(02)00672-8","article-title":"Electrogustometric thresholds: relationship to anterior tongue locus, area of stimulation, and number of fungiform papillae","volume":"75","author":"Miller","year":"2002","journal-title":"Physiol Behav"},{"issue":"5","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/chemse\/20.5.499","article-title":"Reliability and validity of electrogustometry and its application to young and elderly persons","volume":"20","author":"Murphy","year":"1995","journal-title":"Chem Senses"},{"issue":"Suppl","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1080\/00016480260046382","article-title":"Influence of aging on electrogustometry thresholds","author":"Nakazato","year":"2002","journal-title":"Acta Otolaryngol"},{"issue":"6","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"891","DOI":"10.2170\/jjphysiol.31.891","article-title":"Role of ions in generation of taste nerve responses to electrical tongue stimulation in rats","volume":"31","author":"Ninomiya","year":"1981","journal-title":"Jap J Physiol"},{"issue":"10","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1002\/1097-0142(19911115)68:10<2260::AID-CNCR2820681026>3.0.CO;2-W","article-title":"Electrical taste detection thresholds and chemical smell detection thresholds in patients with cancer","volume":"68","author":"Ovesen","year":"1991","journal-title":"Cancer"},{"issue":"7","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1093\/chemse\/bjaa041","article-title":"More than smell\u2014COVID-19 is associated with severe impairment of smell, taste, and chemesthesis","volume":"45","author":"Parma","year":"2020","journal-title":"Chem Senses"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/chemse\/bjs076","article-title":"Age-related changes in electrogustometry thresholds, tongue tip vascularization, density, and form of the fungiform papillae in humans","volume":"38","author":"Pavlidis","year":"2013","journal-title":"Chem Senses"},{"issue":"8","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1007\/s00405-014-3003-9","article-title":"Changes in electrogustometry thresholds, tongue tip vascularization, density and form of the fungiform papillae in smokers","volume":"271","author":"Pavlidis","year":"2014","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"4","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/coa.13731","article-title":"Electrogustometry: Normative data for stimulus duration, tongue site and age decline","volume":"46","author":"Pavlidis","year":"2021","journal-title":"Clin Otolaryngol"},{"issue":"4","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1093\/chemse\/18.4.389","article-title":"Interactions between oral chemical irritation, taste and temperature","volume":"18","author":"Prescott","year":"1993","journal-title":"Chem Senses"},{"issue":"5","key":"2023041310574500400_","first-page":"822","article-title":"Electrogustometry in hemodialysis patients","volume":"39","author":"Ralli","year":"1985","journal-title":"Acta Otorhinolaryngol Belg"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1080\/000164800750001189","article-title":"Assessment of smell and taste in patients with allergic rhinitis","volume":"120","author":"Rydzewski","year":"2000","journal-title":"Acta Otolaryngol"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1097\/MAO.0000000000000223","article-title":"Observation of regenerated fungiform taste buds after severing the chorda tympani nerve using confocal laser scanning microscopy in vivo","volume":"35","author":"Saito","year":"2014","journal-title":"Otol Neurotol"},{"issue":"9","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1097\/MAO.0b013e3182713997","article-title":"Comparison of regeneration of the chorda tympani nerve and gustatory function recovery after severing the nerve between pediatric and adult patients","volume":"33","author":"Saito","year":"2012","journal-title":"Otol Neurotol"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1152\/physrev.00044.2017","article-title":"The functional and neurobiological properties of bad taste","volume":"99","author":"Schier","year":"2019","journal-title":"Physiol Rev"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1001\/archoto.2011.23","article-title":"Changes in taste function related to obesity and chronic otitis media with effusion","volume":"137","author":"Shin","year":"2011","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"4","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/chemse\/27.4.353","article-title":"Taste suppression following lingual capsaicin pre-treatment in humans","volume":"27","author":"Simons","year":"2002","journal-title":"Chem Senses"},{"issue":"9","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1007\/s00405-020-06590-8","article-title":"Objective gustatory and olfactory dysfunction in COVID-19 patients: a prospective cross-sectional study","volume":"278","author":"Singer-Cornelius","year":"2021","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.wjorl.2018.02.008","article-title":"Post-tonsillectomy taste dysfunction: Myth or reality?","volume":"4","author":"Soldatova","year":"2018","journal-title":"World J Otorhinolaryngol Head Neck Surg"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0003-9969(91)90071-2","article-title":"Trigeminal nerve responses in the rat elicited by chemical stimulation of the tongue","volume":"36","author":"Sostman","year":"1991","journal-title":"Arch Oral Biol"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1046\/j.1365-2273.2000.00328.x","article-title":"Automated electrogustometry: a new paradigm for the estimation of taste detection thresholds","volume":"25","author":"Stillman","year":"2000","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"Suppl. 546","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/00016480260046391","article-title":"Clinical use of electrogustometry: strengths and limitations","author":"Tomita","year":"2002","journal-title":"Acta Otolaryngol"},{"issue":"Suppl 1","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0385-8146(86)80029-3","article-title":"Basis and practice of clinical taste examinations","volume":"13","author":"Tomita","year":"1986","journal-title":"Auris Nasus Larynx"},{"issue":"2","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.neulet.2004.01.013","article-title":"Modulation of taste peripheral signal through interpapillar inhibition in hamsters","volume":"358","author":"Vandenbeuch","year":"2004","journal-title":"Neurosci Lett"},{"issue":"3","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1085\/jgp.50.3.519","article-title":"Mach band type lateral inhibition in different sense organs","volume":"50","author":"von Bekesy","year":"1967","journal-title":"J Gen Physiol"},{"issue":"4","key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1152\/jn.1995.73.4.1468","article-title":"Modulation of rat chorda tympani nerve activity by lingual nerve stimulation","volume":"73","author":"Wang","year":"1995","journal-title":"J Neurophysiol"},{"key":"2023041310574500400_","doi-asserted-by":"crossref","first-page":"104483","DOI":"10.1016\/j.foodqual.2021.104483","article-title":"Massively collaborative crowdsourced research on COVID19 and the chemical senses: Insights and outcomes","volume":"97","author":"Weir","year":"2022","journal-title":"Food Qual Prefer"},{"key":"2023041310574500400_","volume-title":"SYSTAT: the System for Statistics","author":"Wilkinson","year":"1990"}],"container-title":["Chemical Senses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/chemse\/advance-article-pdf\/doi\/10.1093\/chemse\/bjad009\/49627641\/bjad009.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/chemse\/article-pdf\/doi\/10.1093\/chemse\/bjad009\/49878857\/bjad009.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/chemse\/article-pdf\/doi\/10.1093\/chemse\/bjad009\/49878857\/bjad009.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T09:06:08Z","timestamp":1702112768000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/chemse\/article\/doi\/10.1093\/chemse\/bjad009\/7085559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,1]]},"references-count":65,"URL":"https:\/\/doi.org\/10.1093\/chemse\/bjad009","relation":{},"ISSN":["0379-864X","1464-3553"],"issn-type":[{"value":"0379-864X","type":"print"},{"value":"1464-3553","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,1,1]]},"published":{"date-parts":[[2023,1,1]]},"article-number":"bjad009"}}