{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:03:36Z","timestamp":1777478616187,"version":"3.51.4"},"reference-count":76,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1093\/chemse\/bjl032","type":"journal-article","created":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T00:58:53Z","timestamp":1159491533000},"page":"21-30","source":"Crossref","is-referenced-by-count":36,"title":["Mutations in Olfactory Signal Transduction Genes Are Not a Major Cause of Human Congenital General Anosmia"],"prefix":"10.1093","volume":"32","author":[{"given":"Ester","family":"Feldmesser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dani","family":"Bercovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nili","family":"Avidan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shmuel","family":"Halbertal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liora","family":"Haim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Gross-Isseroff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivan","family":"Goshen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doron","family":"Lancet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2006,9,28]]},"reference":[{"key":"key\n\t\t\t\t20170522220228_bib1","doi-asserted-by":"crossref","first-page":"498","DOI":"10.2337\/diabetes.47.3.498","article-title":"Mutations in the promoter of adenylyl cyclase (AC)-III gene, overexpression of AC-III mRNA, and enhanced cAMP generation in islets from the spontaneously diabetic GK rat model of type 2 diabetes","volume":"47","author":"Abdel-Halim","year":"1998","journal-title":"Diabetes"},{"key":"key\n\t\t\t\t20170522220228_bib2","first-page":"157","article-title":"MR evaluation in patients with isolated anosmia since birth or early childhood","volume":"23","author":"Abolmaali","year":"2002","journal-title":"Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170522220228_bib3","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1001\/archotol.125.9.1005","article-title":"Fluctuating olfactory sensitivity and distorted odor perception in allergic rhinitis","volume":"125","author":"Apter","year":"1999","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20170522220228_bib4","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1177\/088307389801300404","article-title":"Children who can't smell the coffee: isolated congenital anosmia","volume":"13","author":"Assouline","year":"1998","journal-title":"J Child Neurol"},{"key":"key\n\t\t\t\t20170522220228_bib5","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/nrg910","article-title":"Beyond Mendel: an evolving view of human genetic disease transmission","volume":"3","author":"Badano","year":"2002","journal-title":"Nat Rev Genet"},{"key":"key\n\t\t\t\t20170522220228_bib6","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1126\/science.2255909","article-title":"Identification of a specialized adenylyl cyclase that may mediate odorant detection","volume":"250","author":"Bakalyar","year":"1990","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522220228_bib7","first-page":"E277","article-title":"New form of pseudohypoparathyroidism with abnormal catalytic adenylate cyclase","volume":"257","author":"Barrett","year":"1989","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20170522220228_bib8","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1046\/j.1460-9568.2000.00032.x","article-title":"NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression","volume":"12","author":"Behrens","year":"2000","journal-title":"Eur J Neurosci"},{"key":"key\n\t\t\t\t20170522220228_bib9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0896-6273(00)80435-3","article-title":"Mice deficient in G(olf) are anosmic","volume":"20","author":"Belluscio","year":"1998","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522220228_bib10","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1089\/109065703322537197","article-title":"Denaturing high-performance liquid chromatography for the detection of mutations and polymorphisms in UBE3A","volume":"7","author":"Bercovich","year":"2003","journal-title":"Genet Test"},{"key":"key\n\t\t\t\t20170522220228_bib11","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0959-437X(00)00195-7","article-title":"Molecular genetics and prospects for therapy of the inherited retinal dystrophies","volume":"11","author":"Bessant","year":"2001","journal-title":"Curr Opin Genet Dev"},{"key":"key\n\t\t\t\t20170522220228_bib12","doi-asserted-by":"crossref","first-page":"5332","DOI":"10.1523\/JNEUROSCI.19-13-05332.1999","article-title":"The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits","volume":"19","author":"Bonigk","year":"1999","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170522220228_bib13","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0006-8993(93)91401-D","article-title":"High-affinity cAMP phosphodiesterase and adenosine localized in sensory organs","volume":"610","author":"Borisy","year":"1993","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20170522220228_bib14","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1523\/JNEUROSCI.12-03-00915.1992","article-title":"Calcium\/calmodulin-activated phosphodiesterase expressed in olfactory receptor neurons","volume":"12","author":"Borisy","year":"1992","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170522220228_bib15","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/00005537-200404000-00026","article-title":"Prevalence of olfactory dysfunction: the skovde population-based study","volume":"114","author":"Bramerson","year":"2004","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20170522220228_bib16","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1097\/00001756-199611250-00028","article-title":"A regulator of G-protein signaling in olfactory receptor neurons","volume":"7","author":"Bruch","year":"1996","journal-title":"Neuroreport"},{"key":"key\n\t\t\t\t20170522220228_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0896-6273(00)80200-7","article-title":"General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel","volume":"17","author":"Brunet","year":"1996","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522220228_bib18","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/(SICI)1097-4695(199808)36:2<190::AID-NEU7>3.0.CO;2-X","article-title":"The neuronal stem cell of the olfactory epithelium","volume":"36","author":"Calof","year":"1998","journal-title":"J Neurobiol"},{"key":"key\n\t\t\t\t20170522220228_bib19","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/(SICI)1097-4695(199803)34:4<377::AID-NEU7>3.0.CO;2-3","article-title":"An enhanced olfactory marker protein immunoreactivity in individual olfactory receptor neurons following olfactory bulbectomy may be related to increased neurogenesis","volume":"34","author":"Carr","year":"1998","journal-title":"J Neurobiol"},{"key":"key\n\t\t\t\t20170522220228_bib20","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1242\/dev.127.11.2323","article-title":"Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium","volume":"127","author":"Cau","year":"2000","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522220228_bib21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/humu.10046","article-title":"Reliability of DHPLC in mutational screening of beta-globin (HBB) alleles","volume":"19","author":"Colosimo","year":"2002","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20170522220228_bib22","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1046\/j.1471-4159.2001.00201.x","article-title":"Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum","volume":"76","author":"Corvol","year":"2001","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t20170522220228_bib23","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1126\/science.8381559","article-title":"Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization","volume":"259","author":"Dawson","year":"1993","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522220228_bib24","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/ng1122","article-title":"Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome","volume":"33","author":"Dode","year":"2003","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170522220228_bib25","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0031-9384(75)90081-5","article-title":"Intranasal trigeminal detection of chemical vapors by humans","volume":"14","author":"Doty","year":"1975","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t20170522220228_bib26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0031-9384(78)90070-7","article-title":"Intranasal trigeminal stimulation from odorous volatiles: psychometric responses from anosmic and normal humans","volume":"20","author":"Doty","year":"1978","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t20170522220228_bib27","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/ajim.4700200405","article-title":"Measurement precision of an olfactory perception threshold test for use in field studies","volume":"20","author":"Fortier","year":"1991","journal-title":"Am J Ind Med"},{"key":"key\n\t\t\t\t20170522220228_bib28","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/353529a0","article-title":"A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules","volume":"353","author":"Franco","year":"1991","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522220228_bib29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/ng868","article-title":"Segregation at three loci explains familial and population risk in Hirschsprung disease","volume":"31","author":"Gabriel","year":"2002","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170522220228_bib30","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1136\/jmg.2003.015313","article-title":"Isolated congenital anosmia locus maps to 18p11.23-q12.2","volume":"41","author":"Ghadami","year":"2004","journal-title":"J Med Genet"},{"key":"key\n\t\t\t\t20170522220228_bib31","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0304-3940(92)90347-A","article-title":"Evidence for genetic determination in human twins of olfactory thresholds for a standard odorant","volume":"141","author":"Gross-Isseroff","year":"1992","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t20170522220228_bib32","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1288\/00005537-198911000-00011","article-title":"Olfactory function following late repair of choanal atresia","volume":"99","author":"Gross-Isseroff","year":"1989","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20170522220228_bib33","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0303-7207(01)00462-2","article-title":"Kallmann syndrome: towards molecular pathogenesis","volume":"179","author":"Hardelin","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170522220228_bib34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1159\/000059073","article-title":"Kallmann syndrome","volume":"56","author":"Hardelin","year":"2000","journal-title":"Adv Otorhinolaryngol"},{"key":"key\n\t\t\t\t20170522220228_bib35","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1002\/humu.20106","article-title":"A paradigm for single nucleotide polymorphism analysis: the case of the acetylcholinesterase gene","volume":"24","author":"Hasin","year":"2004","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20170522220228_bib36","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000072042","article-title":"Retinitis pigmentosa: genes, proteins and prospects","volume":"37","author":"Hims","year":"2003","journal-title":"Dev Ophthalmol"},{"key":"key\n\t\t\t\t20170522220228_bib37","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/j.1742-1241.2001.tb11077.x","article-title":"Congenital anosmia","volume":"55","author":"Ho","year":"2001","journal-title":"Int J Clin Pract"},{"key":"key\n\t\t\t\t20170522220228_bib38","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1080\/00016480410022787","article-title":"Olfactory disorders and their consequences for quality of life","volume":"125","author":"Hummel","year":"2005","journal-title":"Acta Otolaryngol"},{"key":"key\n\t\t\t\t20170522220228_bib39","first-page":"331","article-title":"Congenital anosmia","volume":"69","author":"Jafek","year":"1990","journal-title":"Ear Nose Throat J"},{"key":"key\n\t\t\t\t20170522220228_bib40","doi-asserted-by":"crossref","first-page":"R65","DOI":"10.1093\/hmg\/ddh092","article-title":"The oligogenic properties of Bardet-Biedl syndrome","volume":"13 Spec No 1","author":"Katsanis","year":"2004","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170522220228_bib41","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1442-9071.1984.tb01143.x","article-title":"Bardet-Biedl syndrome","volume":"12","author":"Keith","year":"1984","journal-title":"Aust J Ophthalmol"},{"key":"key\n\t\t\t\t20170522220228_bib42","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/ng1418","article-title":"Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse","volume":"36","author":"Kulaga","year":"2004","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170522220228_bib43","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1097\/00005537-200410000-00017","article-title":"A study on the frequency of olfactory dysfunction","volume":"114","author":"Landis","year":"2004","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20170522220228_bib44","first-page":"460","article-title":"Easy calculations of lod scores and genetic risks on small computers","volume":"36","author":"Lathrop","year":"1984","journal-title":"Am J Hum Genet"},{"key":"key\n\t\t\t\t20170522220228_bib45","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1073\/pnas.81.11.3443","article-title":"Strategies for multilocus linkage analysis in humans","volume":"81","author":"Lathrop","year":"1984","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170522220228_bib46","doi-asserted-by":"crossref","first-page":"7433","DOI":"10.1021\/bi00484a012","article-title":"Identification and biochemical analysis of novel olfactory-specific cytochrome P-450IIA and UDP-glucuronosyl transferase","volume":"29","author":"Lazard","year":"1990","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20170522220228_bib47","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1177\/000348949210100306","article-title":"Congenital lack of olfactory ability","volume":"101","author":"Leopold","year":"1992","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"key\n\t\t\t\t20170522220228_bib48","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1601-5223.1969.tb01853.x","article-title":"Familiar absence of olfaction","volume":"61","author":"Lygonis","year":"1969","journal-title":"Hereditas"},{"key":"key\n\t\t\t\t20170522220228_bib49","doi-asserted-by":"crossref","first-page":"6780","DOI":"10.1016\/S0021-9258(18)83497-4","article-title":"Olfactory-specific cytochrome P-450. cDNA cloning of a novel neuroepithelial enzyme possibly involved in chemoreception","volume":"264","author":"Nef","year":"1989","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170522220228_bib50","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3950\/jibiinkoka.107.665","article-title":"A case report on congenital anosmia","volume":"107","author":"Nishida","year":"2004","journal-title":"Nippon Jibiinkoka Gakkai Kaiho"},{"key":"key\n\t\t\t\t20170522220228_bib51","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/ajmg.1320570323","article-title":"Variable penetrance of hypogonadism in a sibship with Kallmann syndrome due to a deletion of the KAL gene","volume":"57","author":"Parenti","year":"1995","journal-title":"Am J Med Genet"},{"key":"key\n\t\t\t\t20170522220228_bib52","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/PL00000875","article-title":"The role of perireceptor events in vertebrate olfaction","volume":"58","author":"Pelosi","year":"2001","journal-title":"Cell Mol Life Sci"},{"key":"key\n\t\t\t\t20170522220228_bib53","doi-asserted-by":"crossref","first-page":"25425","DOI":"10.1074\/jbc.272.41.25425","article-title":"G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization","volume":"272","author":"Peppel","year":"1997","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170522220228_bib54","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1146\/annurev.genet.35.102401.091224","article-title":"Molecular genetics of hearing loss","volume":"35","author":"Petit","year":"2001","journal-title":"Annu Rev Genet"},{"key":"key\n\t\t\t\t20170522220228_bib55","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1385\/MN:25:1:031","article-title":"Calcium channels and channelopathies of the central nervous system","volume":"25","author":"Pietrobon","year":"2002","journal-title":"Mol Neurobiol"},{"key":"key\n\t\t\t\t20170522220228_bib56","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1517\/phgs.5.1.115.25684","article-title":"Genetic variability and evolution of two pharmacologically important classes of genes","volume":"5","author":"Pungliya","year":"2004","journal-title":"Pharmacogenomics"},{"key":"key\n\t\t\t\t20170522220228_bib57","first-page":"52","article-title":"Patterns of non-conductive olfactory disorders in eastern Austria: a study of 120 patients from the Department of Otorhinolaryngology at the University of Vienna","volume":"113","author":"Quint","year":"2001","journal-title":"Wien Klin Wochenschr"},{"key":"key\n\t\t\t\t20170522220228_bib58","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/humu.10065","article-title":"DHPLC screening of cystic fibrosis gene mutations","volume":"19","author":"Ravnik-Glavac","year":"2002","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20170522220228_bib59","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0006-8993(95)00283-V","article-title":"Functionally mature olfactory neurons from two anosmic patients with Kallmann syndrome","volume":"681","author":"Rawson","year":"1995","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20170522220228_bib60","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0027-5107(03)00014-9","article-title":"SNP and haplotype variation in the human genome","volume":"526","author":"Salisbury","year":"2003","journal-title":"Mutat Res"},{"key":"key\n\t\t\t\t20170522220228_bib61","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1038\/35059104","article-title":"RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III","volume":"409","author":"Sinnarajah","year":"2001","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522220228_bib62","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/90042","article-title":"PAX6 haploinsufficiency causes cerebral malformation and olfactory dysfunction in humans","volume":"28","author":"Sisodiya","year":"2001","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170522220228_bib63","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1146\/annurev.med.55.091902.103843","article-title":"Inherited diseases involving g proteins and g protein-coupled receptors","volume":"55","author":"Spiegel","year":"2004","journal-title":"Annu Rev Med"},{"key":"key\n\t\t\t\t20170522220228_bib64","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1126\/science.1059431","article-title":"Haplotype variation and linkage disequilibrium in 313 human genes","volume":"293","author":"Stephens","year":"2001","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522220228_bib65","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/S0140-6736(01)06186-4","article-title":"Advances in hereditary deafness","volume":"358","author":"Tekin","year":"2001","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170522220228_bib66","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1001\/archotol.128.6.635","article-title":"Characteristics of olfactory disorders in relation to major causes of olfactory loss","volume":"128","author":"Temmel","year":"2002","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20170522220228_bib67","doi-asserted-by":"crossref","first-page":"6447","DOI":"10.1128\/MCB.18.11.6447","article-title":"Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein Roaz","volume":"18","author":"Tsai","year":"1998","journal-title":"Mol Cell Biol"},{"key":"key\n\t\t\t\t20170522220228_bib68","doi-asserted-by":"crossref","first-page":"R225","DOI":"10.1093\/hmg\/ddh254","article-title":"Mechanisms of non-Mendelian inheritance in genetic disease","volume":"13 Spec No 2","author":"Van Heyningen","year":"2004","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170522220228_bib69","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0165-5876(97)00075-X","article-title":"Congenital anosmia","volume":"41","author":"Vowles","year":"1997","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"key\n\t\t\t\t20170522220228_bib70","doi-asserted-by":"crossref","first-page":"4149","DOI":"10.1523\/JNEUROSCI.17-11-04149.1997","article-title":"The characterization of the Olf-1\/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development","volume":"17","author":"Wang","year":"1997","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170522220228_bib71","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0896-6273(00)80561-9","article-title":"Phosphorylation and inhibition of olfactory adenylyl cyclase by CaM kinase II in neurons: a mechanism for attenuation of olfactory signals","volume":"21","author":"Wei","year":"1998","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522220228_bib72","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0896-6273(00)00060-X","article-title":"Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice","volume":"27","author":"Wong","year":"2000","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522220228_bib73","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1046\/j.1365-2141.2003.04431.x","article-title":"Rapid, accurate genotyping of beta-thalassaemia mutations using a novel multiplex primer extension\/denaturing high-performance liquid chromatography assay","volume":"122","author":"Wu","year":"2003","journal-title":"Br J Haematol"},{"key":"key\n\t\t\t\t20170522220228_bib74","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/humu.1130","article-title":"Denaturing high-performance liquid chromatography: a review","volume":"17","author":"Xiao","year":"2001","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20170522220228_bib75","doi-asserted-by":"crossref","first-page":"5830","DOI":"10.1523\/JNEUROSCI.17-15-05830.1997","article-title":"OCAM: a new member of the neural cell adhesion molecule family related to zone-to-zone projection of olfactory and vomeronasal axons","volume":"17","author":"Yoshihara","year":"1997","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170522220228_bib76","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1001\/archotol.1982.00790500026006","article-title":"Posttraumatic anosmia","volume":"108","author":"Zusho","year":"1982","journal-title":"Arch Otolaryngol"}],"container-title":["Chemical Senses"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/chemse\/article-pdf\/32\/1\/21\/17426432\/bjl032.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:44:27Z","timestamp":1683593067000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/chemse\/article-lookup\/doi\/10.1093\/chemse\/bjl032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,28]]},"references-count":76,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2006,9,28]]},"published-print":{"date-parts":[[2007,1]]}},"URL":"https:\/\/doi.org\/10.1093\/chemse\/bjl032","relation":{},"ISSN":["1464-3553","0379-864X"],"issn-type":[{"value":"1464-3553","type":"electronic"},{"value":"0379-864X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,9,28]]}}}