{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:43:22Z","timestamp":1790603002752,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"2","funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["DC008962"],"award-info":[{"award-number":["DC008962"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,2,2]]},"DOI":"10.1093\/chemse\/bjx073","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T17:47:53Z","timestamp":1511977673000},"page":"97-104","source":"Crossref","is-referenced-by-count":24,"title":["Effect of Ovarian Hormones and Mating Experience on the Preference of Female Mice to Investigate Male Urinary Pheromones"],"prefix":"10.1093","volume":"43","author":[{"given":"Elizabeth A","family":"McCarthy","sequence":"first","affiliation":[{"name":"Department of Biology, Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay S","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison F","family":"Coyne","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A","family":"Cherry","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J","family":"Baum","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,12,2]]},"reference":[{"key":"key\n\t\t\t\t20180313030310_CIT0001","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev.physiol.010908.163137","article-title":"Complementary roles of the main and accessory olfactory systems in mammalian mate recognition","volume":"71","author":"Baum","year":"2009","journal-title":"Annu Rev Physiol"},{"key":"key\n\t\t\t\t20180313030310_CIT0002","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1210\/en.2010-1001","article-title":"Acquisition of sexual receptivity: roles of chromatin acetylation, estrogen receptor-alpha, and ovarian hormones","volume":"152","author":"Bonthuis","year":"2011","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180313030310_CIT0003","doi-asserted-by":"crossref","first-page":"5574","DOI":"10.1523\/JNEUROSCI.0209-11.2011","article-title":"The development of female sexual behavior requires prepubertal estradiol","volume":"31","author":"Brock","year":"2011","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20180313030310_CIT0004","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.tins.2012.04.011","article-title":"From genes to social communication: molecular sensing by the vomeronasal organ","volume":"35","author":"Chamero","year":"2012","journal-title":"Trends Neurosci"},{"key":"key\n\t\t\t\t20180313030310_CIT0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neuroscience.2014.03.011","article-title":"Estradiol rapidly modulates odor responses in mouse vomeronasal sensory neurons","volume":"269","author":"Cherian","year":"2014","journal-title":"Neuroscience"},{"key":"key\n\t\t\t\t20180313030310_CIT0006","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.neuron.2005.04.011","article-title":"Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus","volume":"46","author":"Choi","year":"2005","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20180313030310_CIT0007","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.brainres.2008.09.002","article-title":"Dendritic spine density of posterodorsal medial amygdala neurons can be affected by gonadectomy and sex steroid manipulations in adult rats: a Golgi study","volume":"1240","author":"de Castilhos","year":"2008","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20180313030310_CIT0008","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1016\/j.cell.2015.04.052","article-title":"Cyclic regulation of sensory perception by a female hormone alters behavior","volume":"161","author":"Dey","year":"2015","journal-title":"Cell"},{"key":"key\n\t\t\t\t20180313030310_CIT0009","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.physbeh.2011.09.014","article-title":"Disruption of urinary odor preference and lordosis behavior in female mice given lesions of the medial amygdala","volume":"105","author":"DiBenedictis","year":"2012","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0010","first-page":"299","article-title":"Induction of estrus in female mice: estrogen-progesterone interactions","volume":"1","author":"Edwards","year":"1970","journal-title":"HomBehav"},{"key":"key\n\t\t\t\t20180313030310_CIT0011","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1095\/biolreprod65.3.680","article-title":"Cellular turnover in the mammary gland is correlated with systemic levels of progesterone and not 17beta-estradiol during the estrous cycle","volume":"65","author":"Fata","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180313030310_CIT0012","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/(SICI)1097-4695(199905)39:2<249::AID-NEU9>3.0.CO;2-R","article-title":"Vomeronasal neuroepithelium and forebrain Fos responses to male pheromones in male and female mice","volume":"39","author":"Halem","year":"1999","journal-title":"J Neurobiol"},{"key":"key\n\t\t\t\t20180313030310_CIT0013","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.brainres.2007.07.071","article-title":"Effects of sexual experience on conspecific odor preference and male odor-induced activation of the vomeronasal projection pathway and the nucleus accumbens in female rats","volume":"1175","author":"Hosokawa","year":"2007","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20180313030310_CIT0014","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1095\/biolreprod55.3.498","article-title":"Temporal and spatial expression of tissue inhibitors of metalloproteinases during the natural ovulatory cycle of the mouse","volume":"55","author":"Inderdeo","year":"1996","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180313030310_CIT0015","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.yhbeh.2011.02.010","article-title":"Long-term effects of pubertal stressors on female sexual receptivity and estrogen receptor-\u03b1 expression in CD-1 female mice","volume":"59","author":"Ismail","year":"2011","journal-title":"Horm Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0016","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/nature09091","article-title":"Progesterone induces adult mammary stem cell expansion","volume":"465","author":"Joshi","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180313030310_CIT0017","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/chemse\/bjj035","article-title":"Destruction of the main olfactory epithelium reduces female sexual behavior and olfactory investigation in female mice","volume":"31","author":"Keller","year":"2006","journal-title":"Chem Senses"},{"key":"key\n\t\t\t\t20180313030310_CIT0018","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/cne.901970107","article-title":"Connections of the corticomedial amygdala in the golden hamster. I. Efferents of the \u201cvomeronasal amygdala\u201d","volume":"197","author":"Kevetter","year":"1981","journal-title":"J Comp Neurol"},{"key":"key\n\t\t\t\t20180313030310_CIT0019","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0010-17.2017","article-title":"Optogenetic activation of accessory olfactory bulb input to the forebrain differentially modulates investigation of opposite versus same-sex urinary chemosignals and stimulates mating in male mice","volume":"4","author":"Kunkhyen","year":"2017","journal-title":"eNeuro"},{"key":"key\n\t\t\t\t20180313030310_CIT0020","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.1210\/en.2009-0099","article-title":"Enduring influences of peripubertal\/adolescent stressors on behavioral response to estradiol and progesterone in adult female mice","volume":"150","author":"Laroche","year":"2009","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180313030310_CIT0021","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1210\/en.2008-1595","article-title":"Reduced behavioral response to gonadal hormones in mice shipped during the peripubertal\/adolescent period","volume":"150","author":"Laroche","year":"2009","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180313030310_CIT0022","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.yhbeh.2016.12.011","article-title":"A comparison of the effects of male pheromone priming and optogenetic inhibition of accessory olfactory bulb forebrain inputs on the sexual behavior of estrous female mice","volume":"89","author":"McCarthy","year":"2017","journal-title":"Horm Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0023","first-page":"e4389","article-title":"Performing vaginal lavage, crystal violet staining, and vaginal cytological evaluation for mouse estrous cycle staging identification","author":"McLean","year":"2012","journal-title":"J Vis Exp"},{"key":"key\n\t\t\t\t20180313030310_CIT0024","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0031-9384(02)00842-9","article-title":"Attractive properties of sexual pheromones in mice: inate or learned","volume":"77","author":"Moncho-Bogani","year":"2002","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0025","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.cub.2014.12.048","article-title":"Enhanced male-evoked responses in the ventromedial hypothalamus of sexually receptive female mice","volume":"25","author":"Nomoto","year":"2015","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t20180313030310_CIT0026","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3389\/fnana.2012.00033","article-title":"Differential efferent projections of the anterior, posteroventral, and posterodorsal subdivisions of the medial amygdala in mice","volume":"6","author":"Pardo-Bellver","year":"2012","journal-title":"Front Neuroanat"},{"key":"key\n\t\t\t\t20180313030310_CIT0027","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.neuroscience.2004.04.009","article-title":"Influence of sex, estrous cycle and motherhood on dendritic spine density in the rat medial amygdala revealed by the Golgi method","volume":"126","author":"Rasia-Filho","year":"2004","journal-title":"Neuroscience"},{"key":"key\n\t\t\t\t20180313030310_CIT0028","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.yhbeh.2004.02.009","article-title":"Emerging views on the distinct but related roles of the main and accessory olfactory systems in responsiveness to chemosensory signals in mice","volume":"46","author":"Restrepo","year":"2004","journal-title":"Horm Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0029","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1210\/endo-34-4-269","article-title":"The estrogne-progesterone induction of sexual receptivity in the spayed female mouse","volume":"34","author":"Ring","year":"1944","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180313030310_CIT0030","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1126\/science.1225638","article-title":"Pheromonal induction of spatial learning in mice","volume":"338","author":"Roberts","year":"2012","journal-title":"Science"},{"key":"key\n\t\t\t\t20180313030310_CIT0031","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1741-7007-8-75","article-title":"Darcin: a male pheromone that stimulates female memory and sexual attraction to an individual male\u2019s odour","volume":"8","author":"Roberts","year":"2010","journal-title":"BMC Biol"},{"key":"key\n\t\t\t\t20180313030310_CIT0032","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0031-9384(70)90243-X","article-title":"Behavioral and electrophysiological responses of female mice to male urine odors","volume":"5","author":"Scott","year":"1970","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0033","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1037\/0735-7044.122.4.788","article-title":"Sexually dimorphic enhancement by estradiol of male urinary odor detection thresholds in mice","volume":"122","author":"Sorwell","year":"2008","journal-title":"Behav Neurosci"},{"key":"key\n\t\t\t\t20180313030310_CIT0034","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0018-506X(71)90004-3","article-title":"Experiential and strain determinants of the estrogen-progesterone induction of sexual receptivity in spayed female mice","volume":"2","author":"Thompson","year":"1971","journal-title":"Horm Behav"},{"key":"key\n\t\t\t\t20180313030310_CIT0035","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1210\/endo.131.3.1505477","article-title":"Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone","volume":"131","author":"Walmer","year":"1992","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180313030310_CIT0036","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1530\/REP-06-0302","article-title":"Circulating hormones and estrous stage predict cellular and stromal remodeling in murine uterus","volume":"133","author":"Wood","year":"2007","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20180313030310_CIT0037","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.yhbeh.2004.05.008","article-title":"Sex-specific effects of gonadal steroids on conspecific odor preference in the rat","volume":"46","author":"Xiao","year":"2004","journal-title":"Horm Behav"}],"container-title":["Chemical Senses"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/chemse\/article-pdf\/43\/2\/97\/24324197\/bjx073.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T03:03:49Z","timestamp":1520910229000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/chemse\/article\/43\/2\/97\/4683467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,2]]},"references-count":37,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,12,2]]},"published-print":{"date-parts":[[2018,2,2]]}},"URL":"https:\/\/doi.org\/10.1093\/chemse\/bjx073","relation":{},"ISSN":["0379-864X","1464-3553"],"issn-type":[{"value":"0379-864X","type":"print"},{"value":"1464-3553","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,2]]},"published":{"date-parts":[[2017,12,2]]}}}