{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T16:44:53Z","timestamp":1745685893545,"version":"3.37.3"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Educational Department of Jiangxi Province of China","award":["GJJ190898"],"award-info":[{"award-number":["GJJ190898"]}]},{"name":"Natural Science Foundation of Jiangxi Province of China","award":["20161BAB215194"],"award-info":[{"award-number":["20161BAB215194"]}]},{"name":"Health Commission of Jiangxi Province","award":["2017A312"],"award-info":[{"award-number":["2017A312"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ophiopogon japonicus (Thunb.) Ker-Gawl (Liliaceae), which is named as \u201cMaidong\u201d in China, is widely used in traditional Chinese medicine for treating fever, cough, inflammation, epistaxis, constipation, respiratory disease and gastrointestinal disorders. However, the systematic analysis of chemical constituents of O. japonicus has not been well established because of the complexity and trace. In this paper, an effective and reliable high-performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry method was successfully developed to separate and identify the chemical constituents from O. japonicus. As a result, a total of 30 compounds including steroidal saponins, homoisoflavonoids, allylbenzene, cholest and cryptomeridiol were screened or tentatively identified. Of them, three new steroidal saponins were found and tentatively characterized in O. japonicus. This study provides a meaningful material basis for further quality control and pharmacological research.<\/jats:p>","DOI":"10.1093\/chromsci\/bmaa029","type":"journal-article","created":{"date-parts":[[2020,6,2]],"date-time":"2020-06-02T19:11:15Z","timestamp":1591125075000},"page":"641-650","source":"Crossref","is-referenced-by-count":4,"title":["Rapid Screening and Identification of Chemical Constituents From Ophiopogon japonicus by High-Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry"],"prefix":"10.1093","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2423-1965","authenticated-orcid":false,"given":"Yun","family":"Ling","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihua","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youyan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaoqing","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huayan","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shufen","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dengzhao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianguo","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingli","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Life Sciences, Jiujiang University, Jiujiang 332005, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,7,2]]},"reference":[{"issue":"6","key":"2020072407065273000_ref1","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.3892\/ol.2013.1284","article-title":"Antitumor activity of bacterial exopolysaccharides from the endophyte bacillus amyloliquefaciens sp. isolated from Ophiopogon japonicas","volume":"5","author":"Chen","year":"2013","journal-title":"Oncology Letters"},{"key":"2020072407065273000_ref2","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1186\/1472-6882-12-238","article-title":"Antimicrobial activities of endophytic fungi isolated from Ophiopogon japonicus (liliaceae)","volume":"12","author":"Liang","year":"2012","journal-title":"BMC Complementary and Alternative Medicine"},{"issue":"7","key":"2020072407065273000_ref3","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1089\/jmf.2016.3872","article-title":"Antithrombotic effect of 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