{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T12:12:55Z","timestamp":1756901575091,"version":"3.44.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A novel and validated reverse-phase high-performance liquid chromatography (RP-HPLC) approach was established for the concurrent measurement of cyproconazole (CYP) isomers and tebuconazole (TBZ) in suspension concentrate (SC) agrochemical formulations. The approach employed a C18 column with a gradient elution of 0.1% formic acid in water and methanol, attaining baseline resolution of CYP isomer-1, isomer-2 and TBZ without requiring chiral columns or sample pretreatment. Linearity was confirmed within the range of 80\u2013120% of the target concentration, with a R2 value of 0.999. Accuracy varied from 101.2% to 102.8%, with a %RSD of less than 0.8%. LC\u2013MS analysis verified analyte identity through distinctive ion transitions (CYP: m\/z 292, TBZ: m\/z 308). This is the initial method for isomer-specific detection of CYP using RP-HPLC within a formulation matrix. The methodology is straightforward, resilient and appropriate for standard quality assurance and regulatory adherence in agrochemical manufacturing.<\/jats:p>","DOI":"10.1093\/chromsci\/bmaf047","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T10:06:29Z","timestamp":1756548389000},"source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous Analysis of Cyproconazole and Tebuconazole in Suspension Concentrate Formulation by Reverse-Phase High-Performance Liquid Chromatography"],"prefix":"10.1093","volume":"63","author":[{"given":"Sahadev","family":"Katam","sequence":"first","affiliation":[{"name":"Laboratory Number: 8A and 8B , Department of Research and Development, Coromandel International Ltd., Phase-II, IKP Knowledge Park, Genome Valley, Turkapally, Shameerpet, Ranga Reddy (Dist), Hyderabad-50010, Telangana,","place":["India"]},{"name":"Department of Chemistry , Yogi Vemana University, Vemana Puram, Ganganapalle, Kadapa (Dist), Andhra 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