{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:55:43Z","timestamp":1790646943724,"version":"4.1.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T00:00:00Z","timestamp":1578960000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Jiangxi Province Key R&D","award":["20161ACG70003"],"award-info":[{"award-number":["20161ACG70003"]}]},{"name":"Jiangxi Natural Science Foundation","award":["20161BAB205194"],"award-info":[{"award-number":["20161BAB205194"]}]},{"name":"Education Department of Jiangxi Province on Science and Technology Project Foundation","award":["GJJ150864"],"award-info":[{"award-number":["GJJ150864"]}]},{"name":"Innovation and Talent Team of Jiangxi Province","award":["20165BCB19009"],"award-info":[{"award-number":["20165BCB19009"]}]},{"name":"Nanchang Innovative Talent Team","award":["[2016]173"],"award-info":[{"award-number":["[2016]173"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Embelia ribes is a traditional Chinese medicine compound used as a remedy for various diseases. Nevertheless, detailed information regarding its chemical composition is unavailable. Herein, ultra-high-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry was used to characterize the components of E. ribes. A total of 56 compounds, including 16 phenolics, 16 flavonoids, 4 coumarins, 5 fatty acids and 15 other compounds were identified. Furthermore, the total phenolic and total flavonoid content was also assessed; the acetic ether extract of E. ribes was an ideal source of phenolics (308.16\u00a0\u00b1\u00a00.00\u00a0mg gallic acid equivalents\/g of extract) and flavonoids (62.00\u00a0\u00b1\u00a00.01\u00a0mg rutin equivalents\/g of extract). Additionally, acetic ether extract exhibited a high antioxidation effect (ferric reducing activity power: 0.15\u00a0\u00b1\u00a00.01\u00a0mg\/mL; 1,1-diphenyl-2-picrylhydrazyl: 0.18\u00a0\u00b1\u00a00.01\u00a0mg\/mL; 2,2-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid: 0.06\u00a0\u00b1\u00a00.01\u00a0mg\/mL). Further, the nitric oxide concentration in lipopolysaccharide-simulated macrophage RAW 264.7 cells and the pro-inflammatory cytokines (TNF-\u03b1 and IL-6) were suppressed by acetic ether extract. These findings support the notion that E. ribes is an ideal antioxidant and anti-inflammatory agent.<\/jats:p>","DOI":"10.1093\/chromsci\/bmz097","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T11:09:38Z","timestamp":1571396978000},"page":"241-250","source":"Crossref","is-referenced-by-count":11,"title":["Chemical Profiling of Embelia ribes by Ultra-High-Performance Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Its Antioxidant and Anti-inflammatory Activities In Vitro"],"prefix":"10.1093","volume":"58","author":[{"given":"Sa","family":"Guo","sequence":"first","affiliation":[{"name":"Jiangxi University of Traditional Chinese Medicine, No. 818 Yunwan Road, Nanchang 330002, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingzhen","family":"He","sequence":"first","affiliation":[{"name":"Jiangxi University of Traditional Chinese Medicine, No. 818 Yunwan Road, Nanchang 330002, PR 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