{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T04:21:34Z","timestamp":1778905294431,"version":"3.51.4"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"16","license":[{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08EY026986"],"award-info":[{"award-number":["K08EY026986"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We evaluated the potential antiviral effects of azithromycin on the nasopharyngeal virome of Nigerien children who had received multiple rounds of mass drug administration. We found that the respiratory burden of non\u2013severe acute respiratory syndrome coronaviruses was decreased with azithromycin distributions.<\/jats:p>\n               <jats:p>Clinical Trials Registration. NCT02047981.<\/jats:p>","DOI":"10.1093\/cid\/ciaa606","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T21:42:42Z","timestamp":1589578962000},"page":"2282-2284","source":"Crossref","is-referenced-by-count":14,"title":["Reduction of Coronavirus Burden With Mass Azithromycin Distribution"],"prefix":"10.1093","volume":"71","author":[{"given":"Thuy","family":"Doan","sequence":"first","affiliation":[{"name":"Francis I. Proctor Foundation, San Francisco, California, USA"},{"name":"University of California, San Francisco, San Francisco, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Hinterwirth","sequence":"additional","affiliation":[{"name":"Francis I. Proctor Foundation, San Francisco, California, USA"},{"name":"University of California, San Francisco, San Francisco, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed M","family":"Arzika","sequence":"additional","affiliation":[{"name":"Carter Center, Niamey, Niger"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee","family":"Worden","sequence":"additional","affiliation":[{"name":"Francis I. Proctor Foundation, San Francisco, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cindi","family":"Chen","sequence":"additional","affiliation":[{"name":"Francis I. Proctor Foundation, San Francisco, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Zhong","sequence":"additional","affiliation":[{"name":"Francis I. 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Proctor Foundation, San Francisco, California, USA"},{"name":"University of California, San Francisco, San Francisco, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,5,19]]},"reference":[{"key":"2020120619080220800_CIT0001","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1056\/NEJMoa1817213","article-title":"Longer-term assessment of azithromycin for reducing childhood mortality in Africa","volume":"380","author":"Keenan","year":"2019","journal-title":"N Engl J Med"},{"key":"2020120619080220800_CIT0002","doi-asserted-by":"crossref","first-page":"e288","DOI":"10.1016\/S2214-109X(19)30540-6","article-title":"Cause-specific mortality of children younger than 5 years in communities receiving biannual mass azithromycin treatment in Niger: verbal autopsy results from a cluster-randomised controlled trial","volume":"8","author":"Keenan","year":"2020","journal-title":"Lancet Glob Health"},{"key":"2020120619080220800_CIT0003","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/s41591-019-0533-0","article-title":"Gut microbiome alteration in MORDOR I: a community-randomized trial of mass azithromycin distribution","volume":"25","author":"Doan","year":"2019","journal-title":"Nat Med"},{"key":"2020120619080220800_CIT0004","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1183\/09031936.00102014","article-title":"Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells","volume":"45","author":"Sch\u00f6gler","year":"2015","journal-title":"Eur Respir J"},{"key":"2020120619080220800_CIT0005","doi-asserted-by":"crossref","first-page":"14408","DOI":"10.1073\/pnas.1618029113","article-title":"Zika virus cell tropism in the developing human brain and inhibition by azithromycin","volume":"113","author":"Retallack","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2020120619080220800_CIT0006","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13073-016-0344-6","article-title":"Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens","volume":"8","author":"Doan","year":"2016","journal-title":"Genome Med"},{"key":"2020120619080220800_CIT0007","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"2020120619080220800_CIT0008","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13059-019-1674-7","article-title":"Topconfects: a package for confident effect sizes in differential expression analysis provides a more biologically useful ranked gene list","volume":"20","author":"Harrison","year":"2019","journal-title":"Genome Biol"},{"key":"2020120619080220800_CIT0009","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/jmv.25681","article-title":"Emerging coronaviruses: genome structure, replication, and pathogenesis","volume":"92","author":"Chen","year":"2020","journal-title":"J Med Virol"},{"key":"2020120619080220800_CIT0010","doi-asserted-by":"crossref","DOI":"10.1126\/science.abb5793","article-title":"Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period [manuscript published online ahead of print 14 April 2020]","author":"Kissler","year":"2020","journal-title":"Science"},{"key":"2020120619080220800_CIT0011","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/INF.0b013e31823e07fe","article-title":"Human coronavirus in young children hospitalized for acute respiratory illness and asymptomatic controls","volume":"31","author":"Prill","year":"2012","journal-title":"Pediatr Infect Dis J"},{"key":"2020120619080220800_CIT0012","doi-asserted-by":"crossref","DOI":"10.1002\/cpt.1857","article-title":"Clinical pharmacology perspectives on the antiviral activity of azithromycin and use in COVID-19 [manuscript published online ahead of print 17 April 2020]","author":"Damle","year":"2020","journal-title":"Clin Pharmacol Ther"},{"key":"2020120619080220800_CIT0013","doi-asserted-by":"crossref","DOI":"10.5582\/bst.2020.03058","article-title":"Macrolide treatment for COVID-19: will this be the way forward? 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