{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:24:16Z","timestamp":1792027456549,"version":"4.4.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T00:00:00Z","timestamp":1592697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01-AI124319"],"award-info":[{"award-number":["U01-AI124319"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-AI068804"],"award-info":[{"award-number":["R01-AI068804"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-GM128193"],"award-info":[{"award-number":["R01-GM128193"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U2-CES030167"],"award-info":[{"award-number":["U2-CES030167"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K24-AI093969"],"award-info":[{"award-number":["K24-AI093969"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["UC6-AI058607"],"award-info":[{"award-number":["UC6-AI058607"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To understand the clinical, bacterial, and host characteristics associated with recurrent Staphylococcus aureus bacteremia (R-SAB), patients with R-SAB were compared to contemporaneous patients with a single episode of SAB (S-SAB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All SAB isolates underwent spa genotyping. All isolates from R-SAB patients underwent pulsed-field gel electrophoresis (PFGE). PFGE-indistinguishable pairs from 40 patients underwent whole genome sequencing (WGS). Acute phase plasma from R-SAB and S-SAB patients was matched 1:1 for age, race, sex, and bacterial genotype, and underwent cytokine quantification using 25-analyte multiplex bead array.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>R-SAB occurred in 69 (9.1%) of the 756 study patients. Of the 69 patients, 30 experienced relapse (43.5%) and 39 reinfection (56.5%). Age, race, hemodialysis dependence, presence of foreign body, methicillin-resistant Staphyloccus aureus, and persistent bacteremia were individually associated with likelihood of recurrence. Multivariate risk modeling revealed that black hemodialysis patients were nearly 2 times more likely (odds ratio [OR]\u2005=\u20059.652 [95% confidence interval [CI], 5.402\u201317.418]) than white hemodialysis patients (OR\u2005=\u20054.53 [95% CI, 1.696\u201310.879]) to experience R-SAB. WGS confirmed PFGE interpretations in all cases. Median RANTES (regulated on activation, normal T cell expressed and secreted) levels in acute phase plasma from the initial episode of SAB were higher in R-SAB than in matched S-SAB controls (P\u2005=\u2005.0053, false discovery rate\u2005&amp;lt;\u20050.10).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study identified several risk factors for R-SAB. The largest risk for R-SAB is among black hemodialysis patients. Higher RANTES levels in R-SAB compared to matched controls warrants further study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/cid\/ciaa801","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T15:13:24Z","timestamp":1591974804000},"page":"1891-1899","source":"Crossref","is-referenced-by-count":51,"title":["Risk Factors for Recurrent\n                    <i>Staphylococcus aureus<\/i>\n                    Bacteremia"],"prefix":"10.1093","volume":"72","author":[{"given":"Seong-Ho","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"},{"name":"Division of Infectious Diseases, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Dagher","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Ruffin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence P","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"},{"name":"Duke Global Health Institute, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batu K","family":"Sharma-Kuinkel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Souli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"},{"name":"Duke Clinical Research Institute, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison M","family":"Morse","sequence":"additional","affiliation":[{"name":"Departments of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, USA"},{"name":"University of Florida Genetics Institute University of Florida, Gainesville Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily M","family":"Eichenberger","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Hale","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Kohler","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bobby","family":"Warren","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"},{"name":"Pediatric Gastroenterology, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix Mba","family":"Medie","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren M","family":"McIntyre","sequence":"additional","affiliation":[{"name":"Departments of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, USA"},{"name":"University of Florida Genetics Institute University of Florida, Gainesville Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Vance G","family":"Fowler","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"},{"name":"Duke Clinical Research Institute, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,6,21]]},"reference":[{"key":"2021072713115526000_CIT0001","article-title":"Clinical approach to Staphylococcus aureus bacteremia in adults.","volume-title":"UpToDate","author":"Fowler"},{"key":"2021072713115526000_CIT0002","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1001\/archinte.163.17.2066","article-title":"Clinical identifiers of complicated Staphylococcus aureus bacteremia","volume":"163","author":"Fowler","year":"2003","journal-title":"Arch Intern Med"},{"key":"2021072713115526000_CIT0003","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1001\/archinte.167.17.1861","article-title":"Persistent Staphylococcus aureus bacteremia: an analysis of risk factors and outcomes","volume":"167","author":"Hawkins","year":"2007","journal-title":"Arch Intern Med"},{"key":"2021072713115526000_CIT0004","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1128\/CMR.00134-14","article-title":"Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management","volume":"28","author":"Tong","year":"2015","journal-title":"Clin Microbiol Rev"},{"key":"2021072713115526000_CIT0005","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1017\/ice.2015.25","article-title":"Determination of risk factors for recurrent methicillin-resistant Staphylococcus aureus bacteremia in a Veterans Affairs healthcare system population","volume":"36","author":"Albertson","year":"2015","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2021072713115526000_CIT0006","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/01.md.0000091184.93122.09","article-title":"Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study","volume":"82","author":"Chang","year":"2003","journal-title":"Medicine (Baltimore)"},{"key":"2021072713115526000_CIT0007","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1086\/314712","article-title":"Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients","volume":"179","author":"Fowler","year":"1999","journal-title":"J Infect Dis"},{"key":"2021072713115526000_CIT0008","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.diagmicrobio.2006.01.021","article-title":"Risk factors for recurrence in patients with Staphylococcus aureus infections complicated by bacteremia","volume":"55","author":"Kreisel","year":"2006","journal-title":"Diagn Microbiol Infect Dis"},{"key":"2021072713115526000_CIT0009","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1469-0691.2009.02885.x","article-title":"Strain relatedness of meticillin-resistant Staphylococcus aureus isolates recovered from patients with repeated bacteraemia","volume":"16","author":"Liao","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"2021072713115526000_CIT0010","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jinf.2009.03.011","article-title":"Risk factors for recurrence after Staphylococcus aureus bacteraemia: a retrospective matched case-control study","volume":"58","author":"Walker","year":"2009","journal-title":"J Infect"},{"key":"2021072713115526000_CIT0011","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jinf.2013.04.018","article-title":"A nationwide study of comorbidity and risk of reinfection after Staphylococcus aureus bacteraemia","volume":"67","author":"Wiese","year":"2013","journal-title":"J Infect"},{"key":"2021072713115526000_CIT0012","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1093\/cid\/ciz112","article-title":"Changing characteristics of Staphylococcus aureus bacteremia: results from a 21-year, prospective, longitudinal study","volume":"69","author":"Souli","year":"2019","journal-title":"Clin Infect Dis"},{"issue":"suppl_1","key":"2021072713115526000_CIT0013","doi-asserted-by":"crossref","first-page":"S317","DOI":"10.1093\/ofid\/ofy210.897","article-title":"1060. Risk factors for recurrent Staphylococcus aureus bacteremia","volume":"5","author":"Choi","year":"2018","journal-title":"Open Forum Infect Dis"},{"key":"2021072713115526000_CIT0014","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1128\/AAC.01021-12","article-title":"Treatment duration for uncomplicated Staphylococcus aureus bacteremia to prevent relapse: analysis of a prospective observational cohort study","volume":"57","author":"Chong","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"2021072713115526000_CIT0015","doi-asserted-by":"crossref","first-page":"791","DOI":"10.7326\/0003-4819-137-10-200211190-00007","article-title":"Health care\u2013associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections","volume":"137","author":"Friedman","year":"2002","journal-title":"Ann Intern Med"},{"key":"2021072713115526000_CIT0016","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/7651_2014_191","article-title":"Pulse field gel electrophoresis","volume":"1373","author":"Sharma-Kuinkel","year":"2016","journal-title":"Methods Mol Biol"},{"key":"2021072713115526000_CIT0017","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1128\/jcm.33.9.2233-2239.1995","article-title":"Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing","volume":"33","author":"Tenover","year":"1995","journal-title":"J Clin Microbiol"},{"key":"2021072713115526000_CIT0018","article-title":"Recurrent simple cystitis in women.","volume-title":"UpToDate","author":"Hooton"},{"key":"2021072713115526000_CIT0019","first-page":"495; author reply -6","article-title":"Reinfection versus relapse in urinary tract infection","volume":"40","author":"Johnson","year":"2005","journal-title":"Clin Infect Dis"},{"key":"2021072713115526000_CIT0020","first-page":"285","article-title":"Sequence analysis of the variable number tandem repeat in Staphylococcus aureus protein A gene: spa typing","volume":"431","author":"Mathema","year":"2008","journal-title":"Methods Mol Biol"},{"key":"2021072713115526000_CIT0021","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijmm.2009.08.013","article-title":"Genomic variation and evolution of Staphylococcus aureus","volume":"300","author":"Lindsay","year":"2010","journal-title":"Int J Med Microbiol"},{"key":"2021072713115526000_CIT0022","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc Series B"},{"key":"2021072713115526000_CIT0023","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/cid\/ciy277","article-title":"Racial disparities in invasive methicillin-resistant Staphylococcus aureus infections, 2005\u20132014","volume":"67","author":"Gualandi","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2021072713115526000_CIT0024","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1001\/jama.298.15.1763","article-title":"Invasive methicillin-resistant Staphylococcus aureus infections in the United States","volume":"298","author":"Klevens","year":"2007","journal-title":"JAMA"},{"key":"2021072713115526000_CIT0025","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/cid\/ciw808","article-title":"Socioeconomic factors explain racial disparities in invasive community-associated methicillin-resistant Staphylococcus aureus disease rates","volume":"64","author":"See","year":"2017","journal-title":"Clin Infect Dis"},{"key":"2021072713115526000_CIT0026","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/S0140-6736(04)15647-X","article-title":"Postoperative infection with meticillin-resistant Staphylococcus aureus and socioeconomic background","volume":"363","author":"Bagger","year":"2004","journal-title":"Lancet"},{"key":"2021072713115526000_CIT0027","doi-asserted-by":"crossref","first-page":"e1001944","DOI":"10.1371\/journal.pmed.1001944","article-title":"Evidence for community transmission of community-associated but not health-care-associated methicillin-resistant Staphylococcus Aureus strains linked to social and material deprivation: spatial analysis of cross-sectional data","volume":"13","author":"Tosas Auguet","year":"2016","journal-title":"PLoS Med"},{"key":"2021072713115526000_CIT0028","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1086\/533494","article-title":"Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001\u20132004","volume":"197","author":"Gorwitz","year":"2008","journal-title":"J Infect Dis"},{"key":"2021072713115526000_CIT0029","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1186\/s12879-019-4104-2","article-title":"Differences in gram-positive bacterial colonization and antimicrobial resistance among children in a high income inequality setting","volume":"19","author":"Neves","year":"2019","journal-title":"BMC Infect Dis"},{"key":"2021072713115526000_CIT0030","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1086\/651672","article-title":"Prevalence of USA300 strain type of methicillin-resistant Staphylococcus aureus among patients with nasal colonization identified with active surveillance","volume":"31","author":"Freitas","year":"2010","journal-title":"Infect Control Hosp Epidemiol"},{"key":"2021072713115526000_CIT0031","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/gene.2017.6","article-title":"Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping","volume":"18","author":"Cyr","year":"2017","journal-title":"Genes Immun"},{"key":"2021072713115526000_CIT0032","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/infdis\/jiv483","article-title":"Polymorphisms in HLA class II genes are associated with susceptibility to Staphylococcus aureus infection in a white population","volume":"213","author":"DeLorenze","year":"2016","journal-title":"J Infect Dis"},{"key":"2021072713115526000_CIT0033","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1053\/j.ajkd.2016.05.030","article-title":"Risk of ESRD in the United States","volume":"68","author":"Albertus","year":"2016","journal-title":"Am J Kidney Dis"},{"key":"2021072713115526000_CIT0034","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1440-1797.2008.01010.x","article-title":"Race and end-stage renal disease in the United States Medicare population: the disparity persists","volume":"13","author":"Tomson","year":"2008","journal-title":"Nephrology (Carlton)"},{"key":"2021072713115526000_CIT0035","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s40615-014-0036-0","article-title":"Proximity does not equal access: racial disparities in access to high quality dialysis facilities","volume":"1","author":"Saunders","year":"2014","journal-title":"J Racial Ethn Health Disparities"},{"key":"2021072713115526000_CIT0036","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1377\/hlthaff.2018.05381","article-title":"Racial and ethnic disparities in care following the New York State sepsis initiative","volume":"38","author":"Corl","year":"2019","journal-title":"Health Aff (Millwood)"},{"key":"2021072713115526000_CIT0037","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.ajic.2015.11.006","article-title":"Risk and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia among patients admitted with and without MRSA nares colonization","volume":"44","author":"Marzec","year":"2016","journal-title":"Am J Infect Control"},{"key":"2021072713115526000_CIT0038","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0140-6736(04)16897-9","article-title":"Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers","volume":"364","author":"Wertheim","year":"2004","journal-title":"Lancet"},{"key":"2021072713115526000_CIT0039","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJM200101043440102","article-title":"Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group","volume":"344","author":"von Eiff","year":"2001","journal-title":"N Engl J Med"},{"key":"2021072713115526000_CIT0040","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S1471-4906(00)01812-3","article-title":"RANTES: a versatile and controversial chemokine","volume":"22","author":"Appay","year":"2001","journal-title":"Trends Immunol"},{"key":"2021072713115526000_CIT0041","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1186\/s12879-014-0580-6","article-title":"Cytokine responses to Staphylococcus aureus bloodstream infection differ between patient cohorts that have different clinical courses of infection","volume":"14","author":"McNicholas","year":"2014","journal-title":"BMC Infect Dis"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciaa801\/33515498\/ciaa801.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/72\/11\/1891\/39342244\/ciaa801.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/72\/11\/1891\/39342244\/ciaa801.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T10:38:59Z","timestamp":1723027139000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/72\/11\/1891\/5860449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,21]]},"references-count":41,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,6,21]]},"published-print":{"date-parts":[[2021,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciaa801","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,6,1]]},"published":{"date-parts":[[2020,6,21]]}}}