{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:36:22Z","timestamp":1772138182926,"version":"3.50.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T00:00:00Z","timestamp":1617148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We estimated the fraction of antibiotic prescribing in the United States attributable to gonorrhea. Gonorrhea contributes to an outsized proportion of antibiotic prescriptions in young adults, males, and in the southern and western United States. A gonococcal vaccine could substantially reduce antibiotic prescribing in these populations.<\/jats:p>","DOI":"10.1093\/cid\/ciab276","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T00:13:23Z","timestamp":1616717603000},"page":"e1368-e1371","source":"Crossref","is-referenced-by-count":0,"title":["Reduction in Antibiotic Prescribing Attainable With a Gonococcal Vaccine"],"prefix":"10.1093","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6000-8387","authenticated-orcid":false,"given":"Stephen M","family":"Kissler","sequence":"first","affiliation":[{"name":"Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moriah","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonatan H","family":"Grad","sequence":"additional","affiliation":[{"name":"Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,3,31]]},"reference":[{"key":"2021091515512928700_CIT0001","doi-asserted-by":"crossref","DOI":"10.15620\/cdc:82532","volume-title":"Antibiotic resistance threats in the United States","author":"Centers for Disease Control and Prevention","year":"2019"},{"key":"2021091515512928700_CIT0002","doi-asserted-by":"crossref","first-page":"E11988","DOI":"10.1073\/pnas.1810840115","article-title":"Estimating the proportion of bystander selection for antibiotic resistance among potentially pathogenic bacterial flora","volume":"115","author":"Tedijanto","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021091515512928700_CIT0003","doi-asserted-by":"crossref","first-page":"12896","DOI":"10.1073\/pnas.1721095115","article-title":"Impact of existing vaccines in reducing antibiotic resistance: primary and secondary effects","volume":"115","author":"Klugman","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021091515512928700_CIT0004","author":"Centers for Disease Control and Prevention"},{"key":"2021091515512928700_CIT0005","doi-asserted-by":"crossref","first-page":"548-62P","DOI":"10.2471\/BLT.18.228486","article-title":"Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016","volume":"97","author":"Rowley","year":"2019","journal-title":"Bull World Health Organ"},{"key":"2021091515512928700_CIT0006","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.15585\/mmwr.mm6950a6","article-title":"Update to CDC\u2019s treatment guidelines for gonococcal infection, 2020","volume":"69","author":"St Cyr","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2021091515512928700_CIT0007","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/nrurol.2017.139","article-title":"Infection: proof of principle for effectiveness of a gonorrhoea vaccine","volume":"14","author":"Unemo","year":"2017","journal-title":"Nat Rev Urol"},{"key":"2021091515512928700_CIT0008","author":"National Institute of Allergy and Infectious Diseases (NIAID)","year":"2020"},{"key":"2021091515512928700_CIT0009","author":"Centers for Disease Control and Prevention","year":"2020"},{"key":"2021091515512928700_CIT0010","author":"IBM Watson Health","year":"2019"},{"key":"2021091515512928700_CIT0011","author":"US Department of Health and Human","year":"2017"},{"key":"2021091515512928700_CIT0012","author":"Blue Cross Blue Shield","year":"2017"},{"key":"2021091515512928700_CIT0013","doi-asserted-by":"crossref","first-page":"909","DOI":"10.15585\/mmwr.mm6733a1","article-title":"National, regional, state, and selected local area vaccination coverage among adolescents aged 13\u201317 years\u2014United States, 2017","volume":"67","author":"Walker","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2021091515512928700_CIT0014","doi-asserted-by":"crossref","first-page":"e39435","DOI":"10.7554\/eLife.39435","article-title":"The distribution of antibiotic use and its association with antibiotic resistance","volume":"7","author":"Olesen","year":"2018","journal-title":"Elife"},{"key":"2021091515512928700_CIT0015","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1086\/657313","article-title":"Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia","volume":"51","author":"File","year":"2010","journal-title":"Clin Infect Dis"},{"key":"2021091515512928700_CIT0016","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1097\/00006454-200011000-00003","article-title":"Bacteriologic and clinical efficacy of one day vs. three day intramuscular ceftriaxone for treatment of nonresponsive acute otitis media in children","volume":"19","author":"Leibovitz","year":"2000","journal-title":"Pediatr Infect Dis J"},{"key":"2021091515512928700_CIT0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr6506a1","article-title":"Core elements of outpatient antibiotic stewardship","volume":"65","author":"Sanchez","year":"2016","journal-title":"MMWR Recomm Rep"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciab276\/39844015\/ciab276.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/73\/6\/e1368\/40392300\/ciab276.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/73\/6\/e1368\/40392300\/ciab276.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T11:52:55Z","timestamp":1631706775000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/73\/6\/e1368\/6205093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,31]]},"references-count":17,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,3,31]]},"published-print":{"date-parts":[[2021,9,15]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciab276","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.12.11.20247973","asserted-by":"object"}]},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,9,15]]},"published":{"date-parts":[[2021,3,31]]}}}