{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T18:33:02Z","timestamp":1772821982736,"version":"3.50.1"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T00:00:00Z","timestamp":1651190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"Office of the Director","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008548","name":"Harvard T.H. Chan School of Public Health","doi-asserted-by":"publisher","award":["HD052102"],"award-info":[{"award-number":["HD052102"]}],"id":[{"id":"10.13039\/100008548","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007875","name":"Tulane University","doi-asserted-by":"publisher","award":["HD052104"],"award-info":[{"award-number":["HD052104"]}],"id":[{"id":"10.13039\/100007875","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008548","name":"Harvard T.H. Chan School of Public Health","doi-asserted-by":"publisher","award":["P01HD103133"],"award-info":[{"award-number":["P01HD103133"]}],"id":[{"id":"10.13039\/100008548","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>We describe trends in prevalence and identify factors associated with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), syphilis, and Trichomonas vaginalis (TV) diagnosed in pregnancy among US people with human immunodeficiency virus (PWH) and evaluate associations of sexually transmitted infections (STIs) with preterm birth (PTB).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We included pregnant PWH enrolled in the Surveillance Monitoring for ART Toxicities dynamic cohort of the Pediatric HIV\/AIDS Cohort Study network who delivered between 2010 and 2019. Multivariable log-binomial or Poisson generalized estimating equation models were used to estimate the association of calendar year with each STI, controlling for confounders; the association of demographic and clinical factors with each STI; and the association of each STI with PTB.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The sample included 2241 pregnancies among 1821 PWH. Median age at delivery was 29.2 years; 71% of participants identified as Black or African American. STI prevalence was: CT 7.7%, NG 2.3%, syphilis 2.4%, and TV 14.5%; 30% had unknown TV status. There were no temporal changes in STI prevalence. Younger age and initial HIV viral load \u2265400\u2005copies\/mL were associated with increased risk of CT, NG, and TV. Recreational substance use was a risk factor for NG, syphilis, and TV. No STI was associated with PTB.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Unlike nationwide trends, no changes in STI prevalence during the study period were observed. The large proportion with unknown TV status underscores the need for increased adherence to screening guidelines. STIs diagnosed during pregnancy in PWH were not associated with risk of PTB.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/cid\/ciac321","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T19:33:08Z","timestamp":1651087988000},"page":"2211-2218","source":"Crossref","is-referenced-by-count":3,"title":["Sexually Transmitted Infections in Pregnant People With Human Immunodeficiency Virus: Temporal Trends, Demographic Correlates, and Association With Preterm Birth"],"prefix":"10.1093","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9140-5868","authenticated-orcid":false,"given":"Marisa R","family":"Young","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Emory University School of Medicine , Atlanta, Georgia , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carly","family":"Broadwell","sequence":"additional","affiliation":[{"name":"Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Kacanek","sequence":"additional","affiliation":[{"name":"Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen G","family":"Chadwick","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Northwestern University Feinberg School of Medicine , Chicago, Illinois , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Jao","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Northwestern University Feinberg School of Medicine , Chicago, Illinois , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna-Barbara","family":"Moscicki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California, Los Angeles , Los Angeles, California , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Powis","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Pediatrics, Massachusetts General Hospital , Boston, Massachusetts , USA"},{"name":"Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Tassiopoulos","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Harvard T. H. Chan School of Public Health , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn M","family":"Yee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine , Chicago, Illinois , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa B","family":"Haddad","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Emory University School of Medicine , Atlanta, Georgia , USA"},{"name":"Population Council, Center for Biomedical Research , New York, New York , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the Pediatric HIV\/AIDS Cohort Study","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,4,29]]},"reference":[{"key":"2023053018532201100_ciac321-B1","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1093\/infdis\/jiz442","article-title":"Refocusing research on sexually transmitted infections","volume":"222","author":"Eisinger","year":"2020","journal-title":"J Infect Dis"},{"key":"2023053018532201100_ciac321-B2","volume-title":"Sexually transmitted disease surveillance 2019","author":"Centers for Disease Control and Prevention","year":"2021"},{"key":"2023053018532201100_ciac321-B3","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/cid\/ciy079","article-title":"Prevalence and correlates of Trichomonas vaginalis infection among men and women in the United States","volume":"67","author":"Patel","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2023053018532201100_ciac321-B4","volume-title":"STDs and pregnancy\u2014CDC fact sheet","author":"Centers for Disease Control and Prevention"},{"key":"2023053018532201100_ciac321-B5","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1067\/mob.2000.106556","article-title":"The Preterm Prediction Study: association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birth","volume":"183","author":"Andrews","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"2023053018532201100_ciac321-B6","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0002-9378(88)80093-0","article-title":"The association of Chlamydia trachomatis, Neisseria gonorrhoeae, and group B streptococci with preterm rupture of the membranes and pregnancy outcome","volume":"159","author":"Alger","year":"1988","journal-title":"Am J Obstet Gynecol"},{"key":"2023053018532201100_ciac321-B7","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2471\/BLT.12.107623","article-title":"Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis","volume":"91","author":"Gomez","year":"2013","journal-title":"Bull World Health Organ"},{"key":"2023053018532201100_ciac321-B8","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1097\/OLQ.0000000000000134","article-title":"Trichomonas vaginalis as a cause of perinatal morbidity: a systematic review and meta-analysis","volume":"41","author":"Silver","year":"2014","journal-title":"Sex Transm Dis"},{"key":"2023053018532201100_ciac321-B9","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/00007435-199707000-00008","article-title":"Trichomonas vaginalis associated with low birth weight and preterm delivery. 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