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The leak, possibly the largest laboratory accident in the history of infectious diseases, underlines the particular characteristics of Brucella that have made the pathogen a historical entity in biodefense research and a major cause of laboratory-associated infections. It further underlines the need for enhanced vigilance and strict regulatory interventions in similar facilities.<\/jats:p>","DOI":"10.1093\/cid\/ciac463","type":"journal-article","created":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T21:19:36Z","timestamp":1654723176000},"page":"1845-1847","source":"Crossref","is-referenced-by-count":30,"title":["The Lanzhou <i>Brucella<\/i> Leak: The Largest Laboratory Accident in the History of Infectious Diseases?"],"prefix":"10.1093","volume":"75","author":[{"given":"Georgios","family":"Pappas","sequence":"first","affiliation":[{"name":"Institute of Continuing Medical Education of Ioannina , Ioannina , Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,6,8]]},"reference":[{"key":"2022111415392778600_ciac463-B1","author":"Zhu"},{"key":"2022111415392778600_ciac463-B2","author":"Health Commission of Lanzhou City"},{"key":"2022111415392778600_ciac463-B3","author":"Global 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