{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T12:37:16Z","timestamp":1772627836480,"version":"3.50.1"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T00:00:00Z","timestamp":1660953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Danish Ministry of Higher Education and Science","award":["0238-00006B"],"award-info":[{"award-number":["0238-00006B"]}]},{"DOI":"10.13039\/501100001732","name":"Danish National Research Foundation","doi-asserted-by":"crossref","award":["DNRF126"],"award-info":[{"award-number":["DNRF126"]}],"id":[{"id":"10.13039\/501100001732","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Many interventional in-patient coronavirus disease 2019 (COVID-19) trials assess primary outcomes through day 28 post-randomization. Since a proportion of patients experience protracted disease or relapse, such follow-up period may not fully capture the course of the disease, even when randomization occurs a few days after hospitalization.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Among adults hospitalized with COVID-19 in eastern Denmark from 18 March 2020\u201312 January 2021 we assessed all-cause mortality, recovery, and sustained recovery 90 days after admission, and readmission and all-cause mortality 90 days after discharge. Recovery was defined as hospital discharge and sustained recovery as recovery and alive without readmissions for 14 consecutive days.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among 3386 patients included in the study, 2796 (82.6%) reached recovery and 2600 (77.0%) achieved sustained recovery. Of those discharged from hospital, 556 (19.9%) were readmitted and 289 (10.3%) died. Overall, the median time to recovery was 6 days (interquartile range [IQR]: 3\u201310), and 19 days (IQR: 11\u201333) among patients in intensive care in the first 2 days of admission.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Postdischarge readmission and mortality rates were substantial. Therefore, sustained recovery should be favored to recovery outcomes in clinical COVID-19 trials. A 28-day follow-up period may be too short for the critically ill.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/cid\/ciac639","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T07:58:06Z","timestamp":1659945486000},"page":"e82-e89","source":"Crossref","is-referenced-by-count":10,"title":["Readmissions, Postdischarge Mortality, and Sustained Recovery Among Patients Admitted to Hospital With Coronavirus Disease 2019 (COVID-19)"],"prefix":"10.1093","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3736-6156","authenticated-orcid":false,"given":"Kasper S","family":"Moestrup","sequence":"first","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Reekie","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian G","family":"Zucco","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas \u00d8","family":"Jensen","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , Denmark"},{"name":"Department of Infectious Diseases, Nordsj\u00e6llands Hospital , Hiller\u00f8d , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens-Ulrik S","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Respiratory Diseases, Herlev and Gentofte Hospital , Hellerup , Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lothar","family":"Wiese","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Zealand University Hospital , Roskilde , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sisse R","family":"Ostrowski","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark"},{"name":"Department of Immunology, Rigshospitalet , Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carsten U","family":"Niemann","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark"},{"name":"Department of Hematology, Rigshospitalet, Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron","family":"MacPherson","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Lundgren","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Helleberg","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Centre of Excellence for Health, Immunity, and Infections (CHIP ), Copenhagen , 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