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In this Viewpoint, we provide a narrative review of landmark trials investigating antimicrobial treatment durations for VAP caused by P. aeruginosa, and appraise iterations of expert consensus guidelines based on these data. We highlight strengths and weaknesses of existing data on this topic and provide recommendations for future avenues of study.<\/jats:p>","DOI":"10.1093\/cid\/ciac784","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T20:50:20Z","timestamp":1663793420000},"page":"745-749","source":"Crossref","is-referenced-by-count":36,"title":["Less Is More? Antibiotic Treatment Duration in<i>Pseudomonas aeruginosa<\/i>Ventilator-Associated Pneumonia"],"prefix":"10.1093","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1659-4902","authenticated-orcid":false,"given":"Owen R","family":"Albin","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Michigan Medical School , Ann Arbor, Michigan , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith S","family":"Kaye","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Robert Wood Johnson Medical School , New Brunswick, New Jersey , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin K","family":"McCreary","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason M","family":"Pogue","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, University of Michigan College of Pharmacy , Ann Arbor, Michigan , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,9,21]]},"reference":[{"key":"2023021818291832000_","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1164\/ajrccm.153.5.8630626","article-title":"The ATS Board of Directors. 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