{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:19:47Z","timestamp":1792441187130,"version":"4.5.0"},"reference-count":91,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Disease","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Over the last several decades, periprosthetic joint infection has been increasing in incidence and is occurring in more complex patients. While there have been advances in both surgical and medical treatment strategies, there remain important gaps in our understanding. Here, we share our current approaches to the diagnosis and management of periprosthetic joint infection, focusing on frequent clinical challenges and collaborative interdisciplinary care.<\/jats:p>","DOI":"10.1093\/cid\/ciad360","type":"journal-article","created":{"date-parts":[[2023,6,10]],"date-time":"2023-06-10T08:13:18Z","timestamp":1686384798000},"page":"e34-e45","source":"Crossref","is-referenced-by-count":128,"title":["Periprosthetic Joint Infection: Current Clinical Challenges"],"prefix":"10.1093","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1949-7884","authenticated-orcid":false,"given":"Sandra B","family":"Nelson","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Massachusetts General Hospital , Harvard Medical School, Boston, Massachusetts , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodian A","family":"Pinkney","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Massachusetts General Hospital , Harvard Medical School, Boston, Massachusetts , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia F","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Brigham and Women\u2019s Hospital , Harvard Medical School, Boston, Massachusetts , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron J","family":"Tande","sequence":"additional","affiliation":[{"name":"Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic , Rochester, Minnesota , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,7,12]]},"reference":[{"key":"2024041009402413800_ciad360-B1","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1016\/j.arth.2018.05.042","article-title":"Are we winning or losing the battle with periprosthetic joint infection: trends in periprosthetic joint infection and mortality risk for the Medicare population","volume":"33","author":"Kurtz","year":"2018","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B2","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.arth.2021.10.006","article-title":"Incidence and predictors of prosthetic joint infection following primary total knee arthroplasty: a 15-year population-based cohort study","volume":"37","author":"McMaster Arthroplasty Collaborative","year":"2022","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B3","doi-asserted-by":"crossref","first-page":"503","DOI":"10.2106\/JBJS.19.00537","article-title":"Risk factors for periprosthetic joint infection following primary total hip arthroplasty: a 15-year, population-based cohort study","volume":"102","author":"McMaster Arthroplasty Collaborative","year":"2020","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B4","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.arth.2020.12.005","article-title":"Projected economic burden of periprosthetic joint infection of the hip and knee in the United States","volume":"36","author":"Premkumar","year":"2021","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B5","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1016\/j.arth.2020.02.030","article-title":"Projections and epidemiology of revision hip and knee arthroplasty in the United States to 2030","volume":"35","author":"Schwartz","year":"2020","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B6","first-page":"161","article-title":"Outcome of infected total knee utilizing a staging system for prosthetic joint infection","volume":"28","author":"McPherson","year":"1999","journal-title":"Am J Orthop (Belle Mead NJ)"},{"key":"2024041009402413800_ciad360-B7","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s15010-002-3079-9","article-title":"Management of infection associated with prosthetic joints","volume":"31","author":"Zimmerli","year":"2003","journal-title":"Infection"},{"key":"2024041009402413800_ciad360-B8","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.2106\/00004623-200300001-00014","article-title":"Diagnosis and management of infection after total knee arthroplasty","volume":"85-A Suppl 1","author":"Tsukayama","year":"2003","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B9","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1007\/s11999-011-2102-9","article-title":"New definition for periprosthetic joint infection: from the Workgroup of the Musculoskeletal Infection Society","volume":"469","author":"Parvizi","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"2024041009402413800_ciad360-B10","doi-asserted-by":"crossref","first-page":"S325","DOI":"10.1016\/j.arth.2018.09.045","article-title":"Hip and knee section, what is the definition of a periprosthetic joint infection (PJI) of the knee and the hip? Can the same criteria be used for both joints?: Proceedings of International Consensus on Orthopedic Infections","volume":"34","author":"Shohat","year":"2019","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1302\/0301-620X.103B1.BJJ-2020-1381.R1","article-title":"The EBJIS definition of periprosthetic joint infection","volume":"103-B","author":"McNally","year":"2021","journal-title":"Bone Joint J"},{"key":"2024041009402413800_ciad360-B12","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1016\/j.arth.2020.10.036","article-title":"Variation in inflammatory biomarkers among demographic groups significantly affects their accuracy in diagnosing periprosthetic joint infection","volume":"36","author":"Padua","year":"2021","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B13","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/j.arth.2021.01.073","article-title":"The James A. Rand Young Investigator\u2019s Award: are intraoperative cultures necessary if the aspiration culture is positive? A concordance study in periprosthetic joint infection","volume":"36","author":"Boyle","year":"2021","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B14","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.2106\/JBJS.15.01133","article-title":"Contamination of the surgical field with Propionibacterium acnes in primary shoulder arthroplasty","volume":"98","author":"Falconer","year":"2016","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B15","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/j.jse.2019.04.034","article-title":"Proceedings from the 2018 International Consensus Meeting on Orthopedic Infections: the definition of periprosthetic shoulder infection","volume":"28","author":"Garrigues","year":"2019","journal-title":"J Shoulder Elbow Surg"},{"key":"2024041009402413800_ciad360-B16","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1016\/j.arth.2014.04.008","article-title":"Acute delayed infection: increased risk in failed metal on metal total hip arthroplasty","volume":"29","author":"Prieto","year":"2014","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B17","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1111\/os.13500","article-title":"Reliable diagnostic tests and thresholds for preoperative diagnosis of non-inflammatory arthritis periprosthetic joint infection: a meta-analysis and systematic review","volume":"14","author":"Tang","year":"2022","journal-title":"Orthop Surg"},{"key":"2024041009402413800_ciad360-B18","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1007\/s00264-017-3647-3","article-title":"Diagnostic accuracy of alpha-defensin in periprosthetic joint infection: a systematic review and meta-analysis","volume":"41","author":"Yuan","year":"2017","journal-title":"Int Orthop"},{"key":"2024041009402413800_ciad360-B19","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1016\/j.arth.2018.01.007","article-title":"The alpha-defensin test for diagnosing periprosthetic joint infection in the setting of an adverse local tissue reaction secondary to a failed metal-on-metal bearing or corrosion at the head-neck junction","volume":"33","author":"Okroj","year":"2018","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B20","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1302\/0301-620X.103B6.BJJ-2020-1741.R1","article-title":"Synovial fluid \u03b1 defensin has comparable accuracy to synovial fluid white blood cell count and polymorphonuclear percentage for periprosthetic joint infection diagnosis","volume":"103-B","author":"Ivy","year":"2021","journal-title":"Bone Joint J"},{"key":"2024041009402413800_ciad360-B21","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1016\/j.arth.2020.12.018","article-title":"Alpha-defensin offers limited utility in routine workup of periprosthetic joint infection","volume":"36","author":"Kleeman-Forsthuber","year":"2021","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B22","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/os.12966","article-title":"Diagnostic accuracy of the synovial fluid \u03b1-defensin lateral flow test in periprosthetic joint infection: a meta-analysis","volume":"13","author":"Zeng","year":"2021","journal-title":"Orthop Surg"},{"key":"2024041009402413800_ciad360-B23","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.3390\/jcm9082548","article-title":"The role of imaging techniques to define a peri-prosthetic hip and knee joint infection: multidisciplinary consensus statements","volume":"9","author":"Roman\u00f2","year":"2020","journal-title":"J Clin Med"},{"key":"2024041009402413800_ciad360-B24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1056\/NEJMra2203477","article-title":"Periprosthetic joint infection","volume":"388","author":"Patel","year":"2023","journal-title":"N Engl J Med"},{"key":"2024041009402413800_ciad360-B25","doi-asserted-by":"crossref","first-page":"S339","DOI":"10.1016\/j.arth.2018.09.018","article-title":"Hip and knee section, diagnosis, algorithm: Proceedings of International Consensus on Orthopedic Infections","volume":"34","author":"Abdel Karim","year":"2019","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2106\/JBJS.17.00434","article-title":"Diagnosis of periprosthetic joint infection: the potential of next-generation sequencing","volume":"100","author":"Tarabichi","year":"2018","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B27","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1093\/cid\/ciac733","article-title":"Next-generation sequencing supports targeted antibiotic treatment for culture negative orthopedic infections","volume":"76","author":"Kullar","year":"2023","journal-title":"Clin Infect Dis"},{"key":"2024041009402413800_ciad360-B28","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1128\/JCM.01459-14","article-title":"Evaluation of 16S rRNA gene PCR sensitivity and specificity for diagnosis of prosthetic joint infection: a prospective multicenter cross-sectional study","volume":"52","author":"B\u00e9mer","year":"2014","journal-title":"J Clin Microbiol"},{"key":"2024041009402413800_ciad360-B29","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1302\/0301-620X.103B1.BJJ-2020-0017.R3","article-title":"Next-generation sequencing not superior to culture in periprosthetic joint infection diagnosis","volume":"103-B","author":"Kildow","year":"2021","journal-title":"Bone Joint J"},{"key":"2024041009402413800_ciad360-B30","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10096-022-04538-w","article-title":"A multicentre evaluation and expert recommendations of use of the newly developed BioFire joint infection polymerase chain reaction panel","volume":"42","author":"Saeed","year":"2023","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2024041009402413800_ciad360-B31","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.ST.19.00071","article-title":"The double DAIR: a 2-stage debridement with prosthesis-retention protocol for acute periprosthetic joint infections","volume":"11","author":"McQuivey","year":"2021","journal-title":"JBJS Essent Surg Tech"},{"key":"2024041009402413800_ciad360-B32","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1007\/s11999-013-2866-1","article-title":"Success after treatment of periprosthetic joint infection: a Delphi-based international multidisciplinary consensus","volume":"471","author":"Diaz-Ledezma","year":"2013","journal-title":"Clin Orthop Relat Res"},{"key":"2024041009402413800_ciad360-B33","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1302\/2633-1462.210.BJO-2021-0090.R1","article-title":"Modular component exchange and outcome of DAIR for hip and knee periprosthetic joint infection: a systematic review and meta-regression analysis","volume":"2","author":"Gerritsen","year":"2021","journal-title":"Bone Jt Open"},{"key":"2024041009402413800_ciad360-B34","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofab298","article-title":"Outcome of debridement, antibiotics, and implant retention for staphylococcal hip and knee prosthetic joint infections, focused on rifampicin use: a systematic review and meta-analysis","volume":"8","author":"Scheper","year":"2021","journal-title":"Open Forum Infect Dis"},{"key":"2024041009402413800_ciad360-B35","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.jinf.2018.08.017","article-title":"Debridement, antibiotics and implant retention for periprosthetic joint infections: a systematic review and meta-analysis of treatment outcomes","volume":"77","author":"Kunutsor","year":"2018","journal-title":"J Infect"},{"key":"2024041009402413800_ciad360-B36","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/j.arth.2020.09.048","article-title":"1.5-stage exchange arthroplasty for total knee arthroplasty periprosthetic joint infections","volume":"36","author":"Hernandez","year":"2021","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B37","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13063-016-1213-8","article-title":"One-stage or two-stage revision surgery for prosthetic hip joint infection","volume":"17","author":"Strange","year":"2016","journal-title":"Trials"},{"key":"2024041009402413800_ciad360-B38","author":"One stage versus two stage for periprosthetic hip and knee infection.","year":"2022"},{"key":"2024041009402413800_ciad360-B39","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s10096-017-2971-2","article-title":"Prolonged suppressive antibiotic therapy for prosthetic joint infection in the elderly: a national multicentre cohort study","volume":"36","author":"Prendki","year":"2017","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2024041009402413800_ciad360-B40","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00590-019-02559-4","article-title":"Prolonged suppressive antibiotic therapy is successful in the management of prosthetic joint infection","volume":"30","author":"Sandiford","year":"2020","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"2024041009402413800_ciad360-B41","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cis803","article-title":"Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America","volume":"56","author":"Osmon","year":"2013","journal-title":"Clin Infect Dis"},{"key":"2024041009402413800_ciad360-B42","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1056\/NEJMoa2020198","article-title":"Antibiotic therapy for 6 or 12 weeks for prosthetic joint infection","volume":"384","author":"Bernard","year":"2021","journal-title":"N Engl J Med"},{"key":"2024041009402413800_ciad360-B43","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s42836-022-00116-9","article-title":"A protocol for periprosthetic joint infections from the Northern Infection Network for Joint Arthroplasty (NINJA) in The Netherlands","volume":"4","author":"Zijlstra","year":"2022","journal-title":"Arthroplasty"},{"key":"2024041009402413800_ciad360-B44","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.2106\/JBJS.L.01451","article-title":"One-stage exchange arthroplasty for chronic periprosthetic hip infection: results of a large prospective cohort study","volume":"96","author":"Zeller","year":"2014","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B45","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1302\/0301-620X.102B6.BJJ-2019-1596.R1","article-title":"2020 Mark Coventry Award: microorganism-directed oral antibiotics reduce the rate of failure due to further infection after two-stage revision hip or knee arthroplasty for chronic infection: a multicentre randomized controlled trial at a minimum of two years","volume":"102-B","author":"Yang","year":"2020","journal-title":"Bone Joint J"},{"key":"2024041009402413800_ciad360-B46","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.arth.2022.12.006","article-title":"Short course of oral antibiotic treatment after two-stage exchange arthroplasty appears to decrease early reinfection","volume":"38","author":"Ryan","year":"2023","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B47","doi-asserted-by":"crossref","first-page":"S989","DOI":"10.1016\/j.arth.2022.01.027","article-title":"Extended oral antibiotics increase bacterial resistance in patients who fail 2-stage exchange for periprosthetic joint infection","volume":"37","author":"Kelly","year":"2022","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B48","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofz181","article-title":"The history of antibiotic treatment of osteomyelitis","volume":"6","author":"Cort\u00e9s-Penfield","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2024041009402413800_ciad360-B49","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1128\/AAC.01504-08","article-title":"Long-term follow-up trial of oral rifampin-cotrimoxazole combination versus intravenous cloxacillin in treatment of chronic staphylococcal osteomyelitis","volume":"53","author":"Euba","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"2024041009402413800_ciad360-B50","doi-asserted-by":"crossref","first-page":"e2582","DOI":"10.1093\/cid\/ciaa985","article-title":"Clinical experience of implementing oral versus intravenous antibiotics (OVIVA) in a specialist orthopedic hospital","volume":"73","author":"Azamgarhi","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2024041009402413800_ciad360-B51","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1056\/NEJMoa1710926","article-title":"Oral versus intravenous antibiotics for bone and joint infection","volume":"380","author":"Li","year":"2019","journal-title":"N Engl J Med"},{"key":"2024041009402413800_ciad360-B52","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofac366","article-title":"Oral versus standard antimicrobial treatment for pyogenic native vertebral osteomyelitis: a single-center, retrospective, propensity score-balanced analysis","volume":"9","author":"Marconi","year":"2022","journal-title":"Open Forum Infect Dis"},{"key":"2024041009402413800_ciad360-B53","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.amjmed.2021.10.007","article-title":"Oral is the new IV. Challenging decades of blood and bone infection dogma: a systematic review","volume":"135","author":"Wald-Dickler","year":"2022","journal-title":"Am J Med"},{"key":"2024041009402413800_ciad360-B54","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1007\/s11695-020-04623-z","article-title":"The effect of bariatric surgery on oral antibiotic absorption: a systematic review","volume":"30","author":"Anvari","year":"2020","journal-title":"Obes Surg"},{"key":"2024041009402413800_ciad360-B55","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01746-18","article-title":"Role of rifampin against staphylococcal biofilm infections in vitro, in animal models, and in orthopedic-device-related infections","volume":"63","author":"Zimmerli","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"2024041009402413800_ciad360-B56","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1093\/cid\/ciab426","article-title":"If, when, and how to use rifampin in acute staphylococcal periprosthetic joint infections, a multicentre observational study","volume":"73","author":"Beldman","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2024041009402413800_ciad360-B57","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofac363","article-title":"Truth in DAIR: duration of therapy and the use of quinolone\/rifampin-based regimens after debridement and implant retention for periprosthetic joint infections","volume":"9","author":"Tai","year":"2022","journal-title":"Open Forum Infect Dis"},{"key":"2024041009402413800_ciad360-B58","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1007\/s40121-022-00701-0","article-title":"Rates and predictors of treatment failure in Staphylococcus aureus prosthetic joint infections according to different management strategies: a multinational cohort study","volume":"11","author":"Esp\u00edndola","year":"2022","journal-title":"Infect Dis Ther"},{"key":"2024041009402413800_ciad360-B59","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1186\/s13018-020-01877-2","article-title":"Rifampin combination therapy in staphylococcal prosthetic joint infections: a randomized controlled trial","volume":"15","author":"Karlsen","year":"2020","journal-title":"J Orthop Surg Res"},{"key":"2024041009402413800_ciad360-B60","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1001\/jama.279.19.1537","article-title":"Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group","volume":"279","author":"Zimmerli","year":"1998","journal-title":"JAMA"},{"key":"2024041009402413800_ciad360-B61","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1093\/cid\/ciab145","article-title":"Safety and tolerability of fluoroquinolones in patients with staphylococcal periprosthetic joint infections","volume":"73","author":"Vollmer","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2024041009402413800_ciad360-B62","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1128\/AAC.38.12.2798","article-title":"Possible implications of doxycycline-rifampin interaction for treatment of brucellosis","volume":"38","author":"Colmenero","year":"1994","journal-title":"Antimicrob Agents Chemother"},{"key":"2024041009402413800_ciad360-B63","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jinf.2015.03.013","article-title":"Dramatic reduction of clindamycin serum concentration in staphylococcal osteoarticular infection patients treated with the oral clindamycin-rifampicin combination","volume":"71","author":"Bernard","year":"2015","journal-title":"J Infect"},{"key":"2024041009402413800_ciad360-B64","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1093\/infdis\/jiaa401","article-title":"Novel use of rifabutin and rifapentine to treat methicillin-resistant Staphylococcus aureus in a rat model of foreign body osteomyelitis","volume":"222","author":"Karau","year":"2020","journal-title":"J Infect Dis"},{"key":"2024041009402413800_ciad360-B65","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1093\/jac\/dkab486","article-title":"Rifabutin versus rifampicin bactericidal and antibiofilm activities against clinical strains of Staphylococcus spp. isolated from bone and joint infections","volume":"77","author":"Thill","year":"2022","journal-title":"J Antimicrob Chemother"},{"key":"2024041009402413800_ciad360-B66","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00384-22","article-title":"A case series of rifabutin use in staphylococcal prosthetic infections","volume":"10","author":"Monk","year":"2022","journal-title":"Microbiol Spectr"},{"key":"2024041009402413800_ciad360-B67","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1016\/j.arth.2022.03.072","article-title":"The use of rifampin in total joint arthroplasty: a systematic review and meta-analysis of comparative studies","volume":"37","author":"Kruse","year":"2022","journal-title":"J Arthroplasty"},{"key":"2024041009402413800_ciad360-B68","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s12879-021-05832-2","article-title":"Impact of rifampicin dose in bone and joint prosthetic device infections due to Staphylococcus spp.: a retrospective single-center study in France","volume":"21","author":"Tonnelier","year":"2021","journal-title":"BMC Infect Dis"},{"key":"2024041009402413800_ciad360-B69","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1111\/1469-0691.12721","article-title":"Characteristics of prosthetic joint infections due to Enterococcus sp. and predictors of failure: a multi-national study","volume":"20","author":"Tornero","year":"2014","journal-title":"Clin Microbiol Infect"},{"key":"2024041009402413800_ciad360-B70","doi-asserted-by":"crossref","first-page":"285","DOI":"10.7150\/jbji.35683","article-title":"A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases","volume":"4","author":"Thompson","year":"2019","journal-title":"J Bone Jt Infect"},{"key":"2024041009402413800_ciad360-B71","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1093\/cid\/cis746","article-title":"A large multicenter study of methicillin-susceptible and methicillin-resistant Staphylococcus aureus prosthetic joint infections managed with implant retention","volume":"56","author":"Lora-Tamayo","year":"2013","journal-title":"Clin Infect Dis"},{"key":"2024041009402413800_ciad360-B72","article-title":"KLIC-score for predicting early failure in prosthetic joint infections treated with debridement, implant retention and antibiotics","volume":"21","author":"Tornero","year":"2015","journal-title":"Clin Microbiol Infect"},{"key":"2024041009402413800_ciad360-B73","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jinf.2018.07.014","article-title":"Clinical outcome and risk factors for failure in late acute prosthetic joint infections treated with debridement and implant retention","volume":"78","author":"Wouthuyzen-Bakker","year":"2019","journal-title":"J Infect"},{"key":"2024041009402413800_ciad360-B74","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1302\/0301-620X.102B7.BJJ-2019-1628.R1","article-title":"2020 Frank Stinchfield Award: identifying who will fail following irrigation and debridement for prosthetic joint infection","volume":"102-B","author":"Shohat","year":"2020","journal-title":"Bone Joint J"},{"key":"2024041009402413800_ciad360-B75","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1089\/sur.2019.368","article-title":"Peri-prosthetic joint infection of the knee causes high levels of psychosocial distress: a prospective cohort study","volume":"21","author":"Knebel","year":"2020","journal-title":"Surg Infect (Larchmt)"},{"key":"2024041009402413800_ciad360-B76","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207260","article-title":"Surgeons are deeply affected when patients are diagnosed with prosthetic joint infection","volume":"13","author":"Mallon","year":"2018","journal-title":"PLoS One"},{"key":"2024041009402413800_ciad360-B77","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.5435\/JAAOS-D-21-00424","article-title":"Movement is life-optimizing patient access to total joint arthroplasty: obesity disparities","volume":"30","author":"Sabesan","year":"2022","journal-title":"J Am Acad Orthop Surg"},{"key":"2024041009402413800_ciad360-B78","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.5435\/JAAOS-D-21-00425","article-title":"Movement is life-optimizing patient access to total joint arthroplasty: diabetes mellitus disparities","volume":"30","author":"Wiznia","year":"2022","journal-title":"J Am Acad Orthop Surg"},{"key":"2024041009402413800_ciad360-B79","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.5435\/JAAOS-D-21-00426","article-title":"Movement is life-optimizing patient access to total joint arthroplasty: dental health disparities","volume":"30","author":"Jones","year":"2022","journal-title":"J Am Acad Orthop Surg"},{"key":"2024041009402413800_ciad360-B80","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.2106\/JBJS.18.01112","article-title":"Reductions in race and ethnic disparities in hospital readmissions following total joint arthroplasty from 2005 to 2015","volume":"101","author":"Aseltine","year":"2019","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B81","doi-asserted-by":"crossref","first-page":"949","DOI":"10.2106\/JBJS.21.00465","article-title":"Racial differences in care and outcomes after total hip and knee arthroplasties: did the comprehensive care for joint replacement program make a difference?","volume":"104","author":"Okewunmi","year":"2022","journal-title":"J Bone Joint Surg Am"},{"key":"2024041009402413800_ciad360-B82","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1097\/CORR.0000000000000634","article-title":"Socioeconomic status is associated with risk of above-knee amputation after periprosthetic joint infection of the knee","volume":"477","author":"Lieber","year":"2019","journal-title":"Clin Orthop Relat Res"},{"key":"2024041009402413800_ciad360-B83","volume-title":"KFF\/The undefeated survey on race and health","author":"Hamel","year":"2020"},{"key":"2024041009402413800_ciad360-B84","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/08964289.2019.1619511","article-title":"Towards a more inclusive and dynamic understanding of medical mistrust informed by science","volume":"45","author":"Jaiswal","year":"2019","journal-title":"Behav Med"},{"key":"2024041009402413800_ciad360-B85","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2105\/AJPH.2021.306604","article-title":"Mistrust, empowerment, and structural change: lessons we should be learning from COVID-19","volume":"112","author":"Ojikutu","year":"2022","journal-title":"Am J Public Health"},{"key":"2024041009402413800_ciad360-B86","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1111\/j.1475-6773.2009.01017.x","article-title":"Mistrust of health care organizations is associated with underutilization of health services","volume":"44","author":"LaVeist","year":"2009","journal-title":"Health Serv Res"},{"key":"2024041009402413800_ciad360-B87","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1111\/j.1525-1497.2005.0174.x","article-title":"Effects of limited English proficiency and physician language on health care comprehension","volume":"20","author":"Wilson","year":"2005","journal-title":"J Gen Intern Med"},{"key":"2024041009402413800_ciad360-B88","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ssresearch.2015.06.020","article-title":"Disaggregating ethnoracial disparities in physician trust","volume":"54","author":"Sewell","year":"2015","journal-title":"Soc Sci Res"},{"key":"2024041009402413800_ciad360-B89","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/intqhc\/mzl069","article-title":"Language proficiency and adverse events in US hospitals: a pilot study","volume":"19","author":"Divi","year":"2007","journal-title":"Int J Qual Health Care"},{"key":"2024041009402413800_ciad360-B90","author":"Hostetter","year":"2021"},{"key":"2024041009402413800_ciad360-B91","doi-asserted-by":"crossref","first-page":"366","DOI":"10.2105\/AJPH.2020.306087","article-title":"Building trust in COVID-19 vaccines and beyond through authentic community investment","volume":"111","author":"Ojikutu","year":"2021","journal-title":"Am J Public Health"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciad360\/50857057\/ciad360.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cid\/article-pdf\/77\/7\/e34\/57197026\/ciad360.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cid\/article-pdf\/77\/7\/e34\/57197026\/ciad360.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T05:41:54Z","timestamp":1712727714000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/77\/7\/e34\/7222985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,12]]},"references-count":91,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,7,12]]},"published-print":{"date-parts":[[2023,10,5]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciad360","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10,1]]},"published":{"date-parts":[[2023,7,12]]}}}