{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T21:11:25Z","timestamp":1794085885185,"version":"4.8.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T00:00:00Z","timestamp":1686614400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"(NIH)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Despite being the leading cause of mortality from bloodstream infections worldwide, little is known about regional variation in treatment practices for Staphylococcus aureus bacteremia (SAB). The aim of this study was to identify global variation in management, diagnostics, and definitions of SAB.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>During a 20-day period in 2022, physicians throughout the world were surveyed on SAB treatment practices. The survey was distributed through listservs, e-mails, and social media.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 2031 physicians from 71 different countries on 6 continents (North America [701, 35%], Europe [573, 28%], Asia [409, 20%], Oceania [182, 9%], South America [124, 6%], and Africa [42, 2%]) completed the survey. Management-based responses differed significantly by continent for preferred treatment of methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) bacteremia, use of adjunctive rifampin for prosthetic material infection, and use of oral antibiotics (P &amp;lt; .01 for all comparisons). The 18F-FDG PET\/CT scans were most commonly used in Europe (94%) and least frequently used in Africa (13%) and North America (51%; P &amp;lt; .01). Although most respondents defined persistent SAB as 3\u20134 days of positive blood cultures, responses ranged from 2 days in 31% of European respondents to 7 days in 38% of Asian respondents (P &amp;lt; .01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Large practice variations for SAB exist throughout the world, reflecting the paucity of high-quality data and the absence of an international standard of care for the management of SAB.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/cid\/ciad363","type":"journal-article","created":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T15:09:01Z","timestamp":1686668941000},"page":"1092-1101","source":"Crossref","is-referenced-by-count":61,"title":["Global Differences in the Management of <i>Staphylococcus aureus<\/i> Bacteremia: No International Standard of Care"],"prefix":"10.1093","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0648-3555","authenticated-orcid":false,"given":"Annette C","family":"Westgeest","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Duke University , Durham, North Carolina ,","place":["USA"]},{"name":"Department of Infectious Diseases, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T P","family":"Buis","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, Department of Internal Medicine, Division of Infectious Diseases, Vrije Universiteit Amsterdam, Amsterdam Institute for Infection and Immunity , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim C E","family":"Sigaloff","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, Department of Internal Medicine, Division of Infectious Diseases, Vrije Universiteit Amsterdam, Amsterdam Institute for Infection and Immunity , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Ruffin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Duke University , Durham, North Carolina ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo G","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunsong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine , Hangzhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emile F","family":"Schippers","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]},{"name":"Department of Internal Medicine, Haga Teaching Hospital , The Hague ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merel M C","family":"Lambregts","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven Y C","family":"Tong","sequence":"additional","affiliation":[{"name":"Victorian Infectious Diseases Service, The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity , Melbourne ,","place":["Australia"]},{"name":"Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity , Melbourne 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