{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:40:29Z","timestamp":1792255229718,"version":"4.4.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T00:00:00Z","timestamp":1688428800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Hologic, Inc"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Mycoplasma genitalium (MG) is on the CDC Watch List of Antimicrobial Resistance Threats, yet there is no systematic surveillance to monitor change.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We initiated surveillance in sexual health clinics in 6 cities, selecting a quota sample of urogenital specimens tested for gonorrhea and\/or chlamydia. We abstracted patient data from medical records and detected MG and macrolide-resistance mutations (MRMs) by nucleic acid amplification testing. We used Poisson regression to estimate adjusted prevalence ratios (aPRs) and 95% CIs, adjusting for sampling criteria (site, birth sex, symptom status).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>From October\u2013December 2020 we tested 1743 urogenital specimens: 57.0% from males, 46.1% from non-Hispanic Black persons, and 43.8% from symptomatic patients. MG prevalence was 16.6% (95% CI: 14.9\u201318.5%; site-specific range: 9.9\u201323.5%) and higher in St Louis (aPR: 1.9; 1.27\u20132.85), Greensboro (aPR: 1.8; 1.18\u20132.79), and Denver (aPR: 1.7; 1.12\u20132.44) than Seattle. Prevalence was highest in persons &amp;lt;18 years (30.4%) and declined 3% per each additional year of age (aPR: .97; .955\u2013.982). MG was detected in 26.8%, 21.1%, 11.8%, and 15.4% of urethritis, vaginitis, cervicitis, and pelvic inflammatory disease (PID), respectively. It was present in 9% of asymptomatic males and 15.4% of asymptomatic females, and associated with male urethritis (aPR: 1.7; 1.22\u20132.50) and chlamydia (aPR: 1.7; 1.13\u20132.53). MRM prevalence was 59.1% (95% CI: 53.1\u201364.8%; site-specific range: 51.3\u201370.6%). MRMs were associated with vaginitis (aPR: 1.8; 1.14\u20132.85), cervicitis (aPR: 3.5; 1.69\u20137.30), and PID cervicitis (aPR: 1.8; 1.09\u20133.08).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>MG infection is common in persons at high risk of sexually transmitted infections; testing symptomatic patients would facilitate appropriate therapy. Macrolide resistance is high and azithromycin should not be used without resistance testing.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/cid\/ciad405","type":"journal-article","created":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T03:08:02Z","timestamp":1688526482000},"page":"1449-1459","source":"Crossref","is-referenced-by-count":30,"title":["<i>Mycoplasma genitalium<\/i> in the US (MyGeniUS): Surveillance Data From Sexual Health Clinics in 4 US Regions"],"prefix":"10.1093","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4896-7654","authenticated-orcid":false,"given":"Lisa E","family":"Manhart","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Center for AIDS and STD, University of Washington , Seattle, Washington , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina","family":"Leipertz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Washington , Seattle, Washington , USA"},{"name":"Elson S. Floyd College of Medicine, Washington State University , Spokane, Washington , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olusegun O","family":"Soge","sequence":"additional","affiliation":[{"name":"Department of Global Health, and Division of Infectious Diseases, University of Washington , Seattle, Washington , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J","family":"Jordan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Indiana University , Indianapolis, Indiana , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candice","family":"McNeil","sequence":"additional","affiliation":[{"name":"Department of Medicine, Section on Infectious Diseases, Wake Forest University School of Medicine , Winston-Salem, North Carolina , 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