{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:03:50Z","timestamp":1791403430497,"version":"4.3.3"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Candida auris has become a growing concern worldwide because of increases in incidence of colonization and reports of invasive infections. There are limited data on clinical factors associated with poor outcomes in patients with C. auris bloodstream infection (BSI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We assembled a multicenter retrospective cohort of patients with C. auris BSI from 2 geographics areas in US healthcare settings. We collected data on demographic, clinical, and microbiologic characteristics to describe the cohort and constructed multivariate logistic regression models to understand risk factors for 2 clinical outcomes, all-cause mortality during facility admission, and blood culture clearance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our cohort consisted of 187 patients with C. auris BSI (56.1% male, 55.6% age &amp;gt;65 years); 54.6% died by facility discharge and 66.9% (of 142 with available data) experienced blood culture clearance. Pitt bacteremia score at infection onset was associated with mortality (odds ratio [95% confidence interval]: 1.19 [1.01\u20131.40] per 1-point increase). Hemodialysis was associated with a reduced odds of microbiologic clearance (0.15 [0.05\u20130.43]) and with mortality (3.08 [1.27\u20137.50]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Pitt bacteremia score at the onset of C. auris BSI may be a useful tool in identifying patients at risk for mortality. Targeted infection prevention practices in patients receiving hemodialysis may be useful to limit poor outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/cid\/ciae411","type":"journal-article","created":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T07:07:47Z","timestamp":1723532867000},"page":"1262-1268","source":"Crossref","is-referenced-by-count":15,"title":["Factors Associated With Poor Clinical and Microbiologic Outcomes in\n                    <i>Candida auris<\/i>\n                    Bloodstream Infection: A Multicenter Retrospective Cohort Study"],"prefix":"10.1093","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8542-4870","authenticated-orcid":false,"given":"Adriana","family":"Jimenez","sequence":"first","affiliation":[{"name":"University of Miami Health System , Miami, Florida ,","place":["USA"]},{"name":"Department of Public Health Sciences, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3755-7780","authenticated-orcid":false,"given":"Rossana","family":"Rosa","sequence":"additional","affiliation":[{"name":"Department of Infection Prevention, Jackson Health System , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1846-3232","authenticated-orcid":false,"given":"Samantha","family":"Ayoub","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Loma Linda University Health , Loma Linda, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8357-0628","authenticated-orcid":false,"given":"Rachel","family":"Guran","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Infection Control, Memorial Healthcare System , Hollywood, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1483-0630","authenticated-orcid":false,"given":"Sebastian","family":"Arenas","sequence":"additional","affiliation":[{"name":"University of Miami Health System , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nickolas","family":"Valencia","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janna C","family":"Stabile","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian T","family":"Estepa","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipen J","family":"Parekh","sequence":"additional","affiliation":[{"name":"University of Miami Health System , Miami, Florida ,","place":["USA"]},{"name":"Department of Urology, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanira","family":"Ferreira","sequence":"additional","affiliation":[{"name":"University of Miami Health System , Miami, Florida ,","place":["USA"]},{"name":"Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7360-2489","authenticated-orcid":false,"given":"Hayley B","family":"Gershengorn","sequence":"additional","affiliation":[{"name":"University of Miami Health System , Miami, Florida ,","place":["USA"]},{"name":"Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]},{"name":"Department of Medicine, Division of Critical Care, Albert Einstein College of Medicine , Bronx, New York ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavitha K","family":"Prabaker","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Infection Prevention, University of California, Los Angeles , Los Angeles, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7281-6231","authenticated-orcid":false,"given":"Paula A","family":"Eckardt","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Infection Control, Memorial Healthcare System , Hollywood, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Zahn","sequence":"additional","affiliation":[{"name":"Orange County Health Care Agency , Santa Ana, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2364-8358","authenticated-orcid":false,"given":"Lilian M","family":"Abbo","sequence":"additional","affiliation":[{"name":"Department of Infection Prevention, Jackson Health System , Miami, Florida ,","place":["USA"]},{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3139-8851","authenticated-orcid":false,"given":"Bhavarth S","family":"Shukla","sequence":"additional","affiliation":[{"name":"University of Miami Health System , Miami, Florida ,","place":["USA"]},{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,13]]},"reference":[{"key":"2024112123540228900_ciae411-B1","volume-title":"WHO fungal priority pathogens list to guide research, development and public health action","author":"World Health Organization","year":"2022"},{"key":"2024112123540228900_ciae411-B2","doi-asserted-by":"crossref","DOI":"10.15620\/cdc:82532","volume-title":"2019 antibiotic resistance threats in the United 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