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Recurrent UTI is defined as \u22652 UTIs in a 6-month period or \u22653 UTIs in 12 months (at least 1 of these episodes should be culture-proven to confirm infectious etiology). In this narrative review, we discuss the epidemiology, pathogenesis, diagnosis, and treatment considerations for recurrent uncomplicated cystitis in the adult female population. We provide a focused overview of the comprehensive management of these patients, with input from infectious disease physicians, urogynecologists, and urologists with expertise in rUTI, highlighting updated recommendations by the Infectious Diseases Society of America, American Urologic Association, Canadian Urologic Association, and American Urogynecologic Society. Finally, given the variety of prevention strategies, different treatment goals, and the need for \u201cpreference sensitive\u201d decisions, we highlight the need for shared decision-making with patients.<\/jats:p>","DOI":"10.1093\/cid\/ciae653","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T15:31:23Z","timestamp":1735313483000},"page":"e31-e42","source":"Crossref","is-referenced-by-count":41,"title":["State-of-the-Art Review: Recurrent Uncomplicated Urinary Tract Infections in Women"],"prefix":"10.1093","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5162-6482","authenticated-orcid":false,"given":"Sonali D","family":"Advani","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine , Durham, North Carolina ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua T","family":"Thaden","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine , Durham, North Carolina ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinaldo","family":"Perez","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine , Durham, North Carolina ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina L","family":"Stair","sequence":"additional","affiliation":[{"name":"Section of Urology and Renal Transplantation, Virginia Mason Franciscan Health , Seattle, Washington ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Una J","family":"Lee","sequence":"additional","affiliation":[{"name":"Section of Urology and Renal Transplantation, Virginia Mason Franciscan Health , Seattle, Washington ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazema Y","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Duke University School of Medicine , Durham, North Carolina ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"2025031715490540800_ciae653-B1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.urology.2015.11.051","article-title":"Incidence and management of uncomplicated recurrent urinary tract infections in a national sample of women in the United States","volume":"90","author":"Suskind","year":"2016","journal-title":"Urology"},{"key":"2025031715490540800_ciae653-B2","doi-asserted-by":"crossref","first-page":"1756287219832172","DOI":"10.1177\/1756287219832172","article-title":"An introduction to the 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