{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T19:37:08Z","timestamp":1784662628615,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Arterial catheter\u2013drawn blood culture sampling may reduce patient discomfort and healthcare providers' workload. Guidelines discourage transcatheter blood culture collection due to contamination risks, mainly derived from data on venous catheter\u2013drawn cultures. However, contamination rates of arterial catheter\u2013drawn cultures have not been comprehensively evaluated compared with venipuncture- or venous catheter\u2013drawn cultures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We searched PubMed, Embase, and the Cochrane Library from inception through 5 December 2023, for studies comparing arterial catheter\u2013drawn blood cultures with venipuncture- or venous catheter\u2013drawn blood cultures. The primary outcome was blood culture contamination rate. We performed a random-effects meta-analysis and evaluated the certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 6 studies involving 8533 blood cultures. When comparing arterial catheter\u2013 with venipuncture-drawn cultures, the crude contamination rates were 28\/1355 (2.1%) and 103\/4539 (2.3%), respectively. Arterial catheter\u2013drawn cultures may not increase contamination rates compared to venipuncture-drawn cultures (risk difference [RD], 0.01 [95% confidence interval {CI}, \u2212.01 to .02]; low certainty). When comparing arterial catheter\u2013 with venous catheter\u2013drawn cultures, the crude contamination rates were 15\/489 (3.1%) and 211\/2639 (8.0%), respectively. Compared to venous catheter\u2013drawn cultures, arterial catheter\u2013drawn cultures may have lower contamination rates (RD, \u22120.05 [95% CI, \u2212.11 to .01]; low certainty).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In critically ill patients, arterial catheter\u2013drawn blood cultures may have contamination rates comparable to venipuncture-drawn cultures and potentially lower than venous catheter\u2013drawn cultures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trials Registration<\/jats:title>\n                    <jats:p>PROSPERO (CRD42023486227).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/cid\/ciaf260","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:36:13Z","timestamp":1747787773000},"page":"446-452","source":"Crossref","is-referenced-by-count":4,"title":["Contamination of Blood Cultures Drawn From Arterial Catheters Versus Venipuncture or Venous Catheters in Critically Ill Patients: A Systematic Review and Meta-analysis"],"prefix":"10.1093","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9034-2159","authenticated-orcid":false,"given":"Takatoshi","family":"Koroki","sequence":"first","affiliation":[{"name":"Department of Intensive Care Medicine, Kameda Medical Center , Kamogawa, Chiba ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4032-3894","authenticated-orcid":false,"given":"Motoki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Kameda Medical Center , Kamogawa, Chiba ,","place":["Japan"]},{"name":"Department of Infectious Diseases, Kameda Medical Center , Kamogawa, Chiba ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9532-2859","authenticated-orcid":false,"given":"Yuki","family":"Kotani","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Kameda Medical Center , Kamogawa, Chiba ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Yaguchi","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Kameda Medical Center , Kamogawa, Chiba ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2250-0204","authenticated-orcid":false,"given":"Taisuke","family":"Shibata","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Kameda Medical Center , Kamogawa, Chiba 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