{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:24:18Z","timestamp":1792027458063,"version":"4.4.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The study aim was to evaluate the effectiveness of anti\u2013methicillin-resistant Staphylococcus aureus (MRSA) cephalosporins in combination with daptomycin (anti-MRSA Ceph + DAP) compared to other antimicrobial regimens (OARs) as initial treatment of MRSA bloodstream infection (BSI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective observational study enrolled patients with MRSA-BSI from 1 January 2020 to 31 December 2024 at 4 large Italian hospitals. The primary endpoint was 90-day all-cause mortality. Cox regression was used for primary endpoint analysis; results were confirmed with inverse probability of treatment weighting (IPTW). Treatment efficacy was also assessed using the desirability of outcome ranking (DOOR) approach, assigning 1 additional point beyond recovery for 1 of the following negative outcomes: (i) persistent MRSA infection, (ii) persistent bacteremia (\u22655 days), (iii) drug resistance, (iv) any adverse event, and (v) 90-day relapse. A score of 7 was assigned for death at any time point.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 465 patients were enrolled: Median age was 76 (IQR, 61\u201383) years, 59% male, with a Charlson Comorbidity Index score of 7 (IQR, 4\u20138). Of them, 50 (11%) and 116 (25%) patients had endocarditis and metastatic infection, respectively. Importantly, 90-day mortality occurred in 181 (39%) patients, while 260 (56%) experienced at least 1 negative outcome included in DOOR analysis. Overall, patients in the anti-MRSA Ceph + DAP arm had a 59.9% (95% CI, 52.4%\u201367.4%) probability of having a better outcome than those in the OAR arm. Particularly, anti-MRSA Ceph + DAP was associated with reduced mortality (aHR, 0.54 [95% CI, .34\u2013.85]), confirmed after adjustment with IPTW analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Anti-MRSA Ceph + DAP could represent a valid initial therapy for MRSA-BSI, especially in patients with high risk of worse outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/cid\/ciag228","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T11:44:55Z","timestamp":1775216695000},"page":"376-387","source":"Crossref","is-referenced-by-count":1,"title":["Anti\u2013Methicillin-Resistant\n                    <i>Staphylococcus aureus<\/i>\n                    (MRSA) Cephalosporins Plus Daptomycin as Initial Therapy for MRSA Bacteremia: Does a \u201cHit Hard and Fast\u201d Strategy Improve Outcomes?"],"prefix":"10.1093","volume":"83","author":[{"given":"Davide Fiore","family":"Bavaro","sequence":"first","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5455-8964","authenticated-orcid":false,"given":"Alessandra","family":"Belati","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0393-6109","authenticated-orcid":false,"given":"Davide","family":"Sacchet","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Cilli","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Diella","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Pocaterra","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddalena","family":"Casana","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diletta","family":"Barbanotti","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Morelli","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3897-9678","authenticated-orcid":false,"given":"Luisa","family":"Frallonardo","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d \u00a0 Bari ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3453-5647","authenticated-orcid":false,"given":"Francesco","family":"Di Gennaro","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d \u00a0 Bari ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Ronga","sequence":"additional","affiliation":[{"name":"Section of Microbiology and Virology, Polyclinic of Bari, University of Bari \"Aldo Moro\" , Bari ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9839-4380","authenticated-orcid":false,"given":"Riccardo","family":"Bollini","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]},{"name":"National PhD Programme in One Health Approaches to Infectious Diseases and Life Science Research, Department of Public Health, Experimental and Forensic Medicine, University of Pavia , Pavia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Scuderi","sequence":"additional","affiliation":[{"name":"Microbiology, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erminia","family":"Casari","sequence":"additional","affiliation":[{"name":"Microbiology, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Cento","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]},{"name":"Microbiology, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Bussini","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Patrucco","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna , Bologna ,","place":["Italy"]},{"name":"Infectious Diseases Unit, IRCCS Azienda Ospedaliero\u2013Universitaria di Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Pascale","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna , Bologna ,","place":["Italy"]},{"name":"Infectious Diseases Unit, IRCCS Azienda Ospedaliero\u2013Universitaria di Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Saracino","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d \u00a0 Bari ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Berna","sequence":"additional","affiliation":[{"name":"Centro Cardiologico Monzino Cardiology Unit, , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Carbonara","sequence":"additional","affiliation":[{"name":"UOC Malattie Infettive, Ospedale Vittorio Emanuele II , Bisceglie ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddalena","family":"Giannella","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna , Bologna ,","place":["Italy"]},{"name":"Infectious Diseases Unit, IRCCS Azienda Ospedaliero\u2013Universitaria di Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1264-0008","authenticated-orcid":false,"given":"Pierluigi","family":"Viale","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna , Bologna ,","place":["Italy"]},{"name":"Infectious Diseases Unit, IRCCS Azienda Ospedaliero\u2013Universitaria di Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Bartoletti","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, IRCCS Humanitas Research Hospital , Rozzano ,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University , Pieve Emanuele ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"2026100713434217600_ciag228-B1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.15585\/mmwr.mm6809e1","article-title":"Vital signs: epidemiology and recent trends in methicillin-resistant and in methicillin-susceptible Staphylococcus aureus bloodstream infections\u2014United States","volume":"68","author":"Kourtis","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2026100713434217600_ciag228-B2","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.cmi.2022.03.015","article-title":"Staphylococcus aureus bacteraemia mortality: a systematic review and meta-analysis","volume":"28","author":"Bai","year":"2022","journal-title":"Clin Microbiol Infect"},{"key":"2026100713434217600_ciag228-B3","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1093\/cid\/cit499","article-title":"Impact of an evidence-based bundle intervention in the quality-of-care management and outcome of Staphylococcus aureus bacteremia","volume":"57","author":"L\u00f3pez-Cort\u00e9s","year":"2013","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B4","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1093\/cid\/ciq146","article-title":"Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children","volume":"52","author":"Liu","year":"2011","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B5","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jinf.2008.04.003","article-title":"Clinical failures of appropriately-treated methicillin-resistant Staphylococcus aureus infections","volume":"57","author":"Dombrowski","year":"2008","journal-title":"J Infect"},{"key":"2026100713434217600_ciag228-B6","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1093\/cid\/ciad525","article-title":"Executive summary: state-of-the-art review: contemporary management of Staphylococcus aureus bacteremia: controversies in clinical practice","volume":"77","author":"Minter","year":"2023","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B7","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jgar.2020.09.024","article-title":"Systematic review and meta-analysis of the efficacy and safety of vancomycin combined with \u03b2-lactam antibiotics in the treatment of methicillin-resistant Staphylococcus aureus bloodstream infections","volume":"23","author":"Ye","year":"2020","journal-title":"J Glob Antimicrob Resist"},{"key":"2026100713434217600_ciag228-B8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/cid\/ciz746","article-title":"Daptomycin plus \u03b2-lactam combination therapy for methicillin-resistant Staphylococcus aureus bloodstream infections: a retrospective, comparative cohort study","volume":"71","author":"Jorgensen","year":"2020","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B9","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/cid\/ciaa1081","article-title":"Daptomycin plus fosfomycin versus daptomycin alone for methicillin-resistant Staphylococcus aureus bacteremia and endocarditis: a randomized clinical trial","volume":"72","author":"Pujol","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/14740338.2023.2299377","article-title":"Safety and effectiveness of fifth generation cephalosporins for the treatment of methicillin-resistant Staphylococcus aureus bloodstream infections: a narrative review exploring past, present, and future","volume":"23","author":"Bavaro","year":"2024","journal-title":"Expert Opin Drug Saf"},{"key":"2026100713434217600_ciag228-B11","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1056\/NEJMoa2300220","article-title":"Ceftobiprole for treatment of complicated Staphylococcus aureus bacteremia","volume":"389","author":"Holland","year":"2023","journal-title":"N Engl J Med"},{"key":"2026100713434217600_ciag228-B12","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.cmi.2024.11.022","article-title":"Ceftaroline for bloodstream infections caused by methicillin-resistant Staphylococcus aureus: a multicentre retrospective cohort study","volume":"31","author":"Villa","year":"2025","journal-title":"Clin Microbiol Infect"},{"key":"2026100713434217600_ciag228-B13","doi-asserted-by":"crossref","first-page":"e02483-18","DOI":"10.1128\/AAC.02483-18","article-title":"Clinical data on daptomycin plus ceftaroline versus standard of care monotherapy in the treatment of methicillin-resistant Staphylococcus aureus bacteremia","volume":"63","author":"Geriak","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"2026100713434217600_ciag228-B14","doi-asserted-by":"crossref","first-page":"106310","DOI":"10.1016\/j.ijantimicag.2021.106310","article-title":"Combination ceftaroline and daptomycin salvage therapy for complicated methicillin-resistant Staphylococcus aureus bacteraemia compared with standard of care","volume":"57","author":"Johnson","year":"2021","journal-title":"Int J Antimicrob Agents"},{"key":"2026100713434217600_ciag228-B15","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1093\/jac\/dku236","article-title":"Potent synergy of ceftobiprole plus daptomycin against multiple strains of Staphylococcus aureus with various resistance phenotypes","volume":"69","author":"Barber","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"2026100713434217600_ciag228-B16","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.cmi.2024.08.011","article-title":"Which trial do we need? Combination therapy with daptomycin plus ceftaroline versus standard-of-care monotherapy in the treatment of methicillin-resistant Staphylococcus aureus bacteraemia","volume":"31","author":"Kim","year":"2025","journal-title":"Clin Microbiol Infect"},{"key":"2026100713434217600_ciag228-B17","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/cid\/ciy766","article-title":"Good studies evaluate the disease while great studies evaluate the patient: development and application of a desirability of outcome ranking endpoint for Staphylococcus aureus bloodstream infection","volume":"68","author":"Doernberg","year":"2019","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B18","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.cmi.2023.05.003","article-title":"Unlocking the DOOR\u2014how to design, apply, analyse, and interpret desirability of outcome ranking endpoints in infectious diseases clinical trials","volume":"29","author":"Ong","year":"2023","journal-title":"Clin Microbiol Infect"},{"key":"2026100713434217600_ciag228-B19","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1213\/ANE.0000000000005101","article-title":"Nonparametric statistical methods in medical research","volume":"131","author":"Schober","year":"2020","journal-title":"Anesth Analg"},{"key":"2026100713434217600_ciag228-B20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/cid\/ciac348","article-title":"Correct calculation of confidence interval for proportion of superior comparisons between desirability of outcome ranking scores","volume":"76","author":"Loewenthal","year":"2023","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B21","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/aje\/kwj149","article-title":"Variable selection for propensity score models","volume":"163","author":"Brookhart","year":"2006","journal-title":"Am J Epidemiol"},{"key":"2026100713434217600_ciag228-B22","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1002\/sim.6607","article-title":"Moving towards best practice when using inverse probability of treatment weighting (IPTW) using the propensity score to estimate causal treatment effects in observational studies","volume":"34","author":"Austin","year":"2015","journal-title":"Stat Med"},{"key":"2026100713434217600_ciag228-B23","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12941-025-00773-z","article-title":"Early initiation of ceftaroline-based combination therapy for methicillin-resistant Staphylococcus aureus bacteremia","volume":"24","author":"Hicks","year":"2025","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"2026100713434217600_ciag228-B24","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1093\/cid\/ciad363","article-title":"Global differences in the management of Staphylococcus aureus bacteremia: no international standard of care","volume":"77","author":"Westgeest","year":"2023","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B25","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1128\/AAC.48.8.2871-2875.2004","article-title":"Synergy of daptomycin with oxacillin and other beta-lactams against methicillin-resistant Staphylococcus aureus","volume":"48","author":"Rand","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"2026100713434217600_ciag228-B26","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/cid\/ciae338","article-title":"Clinical subphenotypes of Staphylococcus aureus bacteremia","volume":"79","author":"Swets","year":"2024","journal-title":"Clin Infect Dis"},{"key":"2026100713434217600_ciag228-B27","doi-asserted-by":"crossref","first-page":"106975","DOI":"10.1016\/j.ijid.2024.02.018","article-title":"Getting to the heart of the matter-are two agents really better than one for the treatment of staphylococcal infective endocarditis?","volume":"142","author":"Donnelly","year":"2024","journal-title":"Int J Infect Dis"},{"key":"2026100713434217600_ciag228-B28","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1001\/jama.2020.0103","article-title":"Effect of vancomycin or daptomycin with vs without an antistaphylococcal \u03b2-lactam on mortality, bacteremia, relapse, or treatment failure in patients with MRSA bacteremia: a randomized clinical trial","volume":"323","author":"Tong","year":"2020","journal-title":"JAMA"},{"key":"2026100713434217600_ciag228-B29","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1016\/S1473-3099(23)00432-2","article-title":"Understanding vancomycin nephrotoxicity augmented by \u03b2-lactams: a synthesis of endosymbiosis, proximal renal tubule mitochondrial metabolism, and \u03b2-lactam chemistry","volume":"24","author":"Alosaimy","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"2026100713434217600_ciag228-B30","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s40261-022-01204-z","article-title":"Risk factors for nephrotoxicity in methicillin-resistant Staphylococcus aureus bacteraemia: a post hoc analysis of the CAMERA2 trial","volume":"43","author":"Legg","year":"2023","journal-title":"Clin Drug Investig"},{"key":"2026100713434217600_ciag228-B31","doi-asserted-by":"crossref","first-page":"ofab327","DOI":"10.1093\/ofid\/ofab327","article-title":"Clinical outcomes with definitive treatment of methicillin-resistant Staphylococcus aureus bacteremia with retained daptomycin and ceftaroline combination therapy vs de-escalation to monotherapy with vancomycin, daptomycin, or ceftaroline","volume":"8","author":"Nichols","year":"2021","journal-title":"Open Forum Infect Dis"},{"key":"2026100713434217600_ciag228-B32","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1093\/cid\/ciz112","article-title":"Changing characteristics of Staphylococcus aureus bacteremia: results from a 21-year, prospective, longitudinal study","volume":"69","author":"Souli","year":"2019","journal-title":"Clin Infect Dis"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciag228\/68456734\/ciag228.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cid\/article-pdf\/83\/3\/376\/68456734\/ciag228.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cid\/article-pdf\/83\/3\/376\/68456734\/ciag228.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:43:53Z","timestamp":1791395033000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/83\/3\/376\/8700240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,9]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,6,9]]},"published-print":{"date-parts":[[2026,10,7]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciag228","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9,15]]},"published":{"date-parts":[[2026,6,9]]}}}