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This multimodal approach was associated with rapid platelet recovery, reduced transfusion requirements, and viral clearance. Combining targeted antivirals with thrombopoietin receptor agonists represents a promising strategy for managing severe CCHF coagulopathy.<\/jats:p>","DOI":"10.1093\/cid\/ciag415","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T11:44:26Z","timestamp":1784288666000},"source":"Crossref","is-referenced-by-count":0,"title":["Treatment of Crimean\u2013Congo Hemorrhagic Fever With Supportive Care, Favipiravir, and Avatrombopag"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2942-2739","authenticated-orcid":false,"given":"Germ\u00e1n","family":"Ram\u00edrez-Olivencia","sequence":"first","affiliation":[{"name":"HLIU, CBRN-Infectious Diseases, Hospital Central de la Defensa G\u00f3mez Ulla CSVE , Madrid ,","place":["Spain"]},{"name":"Department of Medicine and Medical Specialties, University of Alcal\u00e1 de Henares , Madrid 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