{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:59:24Z","timestamp":1790359164266,"version":"4.1.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K01 TW012694"],"award-info":[{"award-number":["K01 TW012694"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["320225\/Z\/24\/Z"],"award-info":[{"award-number":["320225\/Z\/24\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012264","name":"NIH","doi-asserted-by":"publisher","award":["K08 AI193077"],"award-info":[{"award-number":["K08 AI193077"]}],"id":[{"id":"10.13039\/501100012264","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fisher Center of Environmental Infectious Diseases"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Candida auris is an emerging, multidrug-resistant fungal pathogen of growing concern in solid organ transplantation, where colonization may have implications for pretransplant candidacy and post-transplant outcomes. Although C. auris screening is increasingly common in presurgical and critical care settings, no national or professional guidelines in the United States specify who, how, or when to screen, nor is there consensus on how screening results should impact patient care. Here, we examine the ethical significance of C. auris colonization in transplant candidacy decisions and outline the arguments for and against universal C. auris screening of solid organ recipients in the peritransplant period. We propose risk-based screening as a middle-ground approach for hospitals and physicians seeking to develop value-informed, evidence-based guidelines at a time when data are still emerging and evolving. Ultimately, the fundamental goal of pretransplant screening is harm reduction through preparedness and individualized risk assessment, not a proxy for institutional risk tolerance or an artifact of how a screening policy is applied.<\/jats:p>","DOI":"10.1093\/cid\/ciag536","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:21:04Z","timestamp":1788520864000},"source":"Crossref","is-referenced-by-count":0,"title":["Ethical Priorities for\n                    <i>Candida auris<\/i>\n                    Screening in Solid Organ Transplantation"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5857-6227","authenticated-orcid":false,"given":"Lucy X","family":"Li","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Johns Hopkins School of Medicine , Baltimore, Maryland , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9005-9812","authenticated-orcid":false,"given":"Chelsea E","family":"Modlin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Johns Hopkins School of Medicine , Baltimore, Maryland , USA"},{"name":"Berman Institute of Bioethics, Johns Hopkins University , Baltimore, Maryland , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"2026092513162606800_ciag536-B1","doi-asserted-by":"crossref","first-page":"e765","DOI":"10.1093\/cid\/ciaf551","article-title":"Risk factors associated with progression to clinical Candida auris infection among adults with previous colonization\u2014Florida, 2019\u20132023","volume":"82","author":"Saunders","year":"2026","journal-title":"Clin Infect Dis"},{"key":"2026092513162606800_ciag536-B2","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1007\/s40121-022-00625-9","article-title":"Candida auris candidemia in critically ill, colonized patients: cumulative incidence and risk factors","volume":"11","author":"Briano","year":"2022","journal-title":"Infect Dis Ther"},{"key":"2026092513162606800_ciag536-B3","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.ajic.2025.08.032","article-title":"Progression from Candida (Candidozyma) auris colonization to bloodstream infection, New York State (NYS) and Chicago","volume":"53","author":"Southwick","year":"2025","journal-title":"Am J Infect Control"},{"key":"2026092513162606800_ciag536-B4","doi-asserted-by":"crossref","first-page":"e1011843","DOI":"10.1371\/journal.ppat.1011843","article-title":"Mechanisms of pathogenicity for the emerging fungus Candida auris","volume":"19","author":"Horton","year":"2023","journal-title":"PLOS Pathogens"},{"key":"2026092513162606800_ciag536-B5","doi-asserted-by":"crossref","first-page":"e70166","DOI":"10.1111\/tid.70166","article-title":"Candida auris screening in organ transplantation","volume":"28","author":"Cano Cevallos","year":"2026","journal-title":"Transpl Infect Dis"},{"key":"2026092513162606800_ciag536-B6","author":"CDC"},{"key":"2026092513162606800_ciag536-B7","doi-asserted-by":"crossref","first-page":"s99","DOI":"10.1017\/ash.2025.333","article-title":"Reported perioperative practices for Candida auris colonization among surgical and transplant patients","volume":"5","author":"Hassneiah","year":"2025","journal-title":"Antimicrob Steward Healthc Epidemiol"},{"key":"2026092513162606800_ciag536-B8","doi-asserted-by":"crossref","first-page":"e13919","DOI":"10.1111\/tid.13919","article-title":"Challenges and opportunities in stewardship among solid organ transplant recipients with Candida auris bloodstream infections","volume":"24","author":"Vu","year":"2022","journal-title":"Transpl Infect Dis"},{"key":"2026092513162606800_ciag536-B9","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1086\/651262","article-title":"Invasive fungal infections among organ transplant recipients: Results of the Transplant-Associated Infection Surveillance Network (TRANSNET)","volume":"50","author":"Pappas","year":"2010","journal-title":"Clin Infect Dis"},{"key":"2026092513162606800_ciag536-B10","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1016\/j.ajt.2025.07.2480","article-title":"Invasive Candida infections in solid organ transplant recipients between 2008 and 2020","volume":"25","author":"Meyer","year":"2025","journal-title":"Am J Transplant"},{"key":"2026092513162606800_ciag536-B11","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1111\/tid.12613","article-title":"The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)","volume":"18","author":"Andes","year":"2016","journal-title":"Transpl Infect Dis"},{"key":"2026092513162606800_ciag536-B12","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/ajt.14962","article-title":"Excluding patients from transplant due to social support: results from a national survey of transplant providers","volume":"19","author":"Ladin","year":"2019","journal-title":"Am J Transplant"},{"key":"2026092513162606800_ciag536-B13","doi-asserted-by":"crossref","first-page":"e292","DOI":"10.1097\/TP.0000000000003732","article-title":"Psychosocial evaluation of candidates for solid organ transplantation","volume":"105","author":"Bailey","year":"2021","journal-title":"Transplantation"},{"key":"2026092513162606800_ciag536-B14","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1111\/ajt.16472","article-title":"The limits of refusal: an ethical review of solid organ transplantation and vaccine hesitancy","volume":"21","author":"Kates","year":"2021","journal-title":"Am J Transplant"},{"key":"2026092513162606800_ciag536-B15","doi-asserted-by":"crossref","first-page":"e70043","DOI":"10.1111\/myc.70043","article-title":"Key factors to consider for Candida auris screening in healthcare settings: a systematic review","volume":"68","author":"Danielsen","year":"2025","journal-title":"Mycoses"},{"key":"2026092513162606800_ciag536-B16","first-page":"S1198-743X(26)00237-5","article-title":"Evaluation of persistence of C. auris colonization","author":"Bavastro","year":"2026","journal-title":"Clin Microbiol Infect"},{"key":"2026092513162606800_ciag536-B17","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3390\/diagnostics15020140","article-title":"Current updates on molecular diagnostic assays used for detection of Candida auris: a systematic review","volume":"15","author":"Wong","year":"2025","journal-title":"Diagnostics (Basel)"},{"key":"2026092513162606800_ciag536-B18","doi-asserted-by":"crossref","first-page":"ofag338","DOI":"10.1093\/ofid\/ofag338","article-title":"Digital Tattoos in infectious diseases management","volume":"13","author":"Hagiya","year":"2026","journal-title":"Open Forum Infect Dis"},{"key":"2026092513162606800_ciag536-B19","doi-asserted-by":"crossref","first-page":"S837","DOI":"10.1016\/j.ajt.2025.07.1982","article-title":"Candida auris in liver transplant recipients: clinical impact and management challenges","volume":"25","author":"Wortham","year":"2025","journal-title":"Am J Transplant"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciag536\/71397366\/ciag536.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciag536\/71397366\/ciag536.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:16:33Z","timestamp":1790356593000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciag536\/8835968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":19,"URL":"https:\/\/doi.org\/10.1093\/cid\/ciag536","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"article-number":"ciag536"}}