{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:55:04Z","timestamp":1792616104085,"version":"4.5.0"},"reference-count":6,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004844","name":"National Cheng Kung University Hospital","doi-asserted-by":"publisher","award":["NCKUH-11410014"],"award-info":[{"award-number":["NCKUH-11410014"]}],"id":[{"id":"10.13039\/501100004844","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23AI163368"],"award-info":[{"award-number":["K23AI163368"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1093\/cid\/ciag603","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:46:13Z","timestamp":1790318773000},"source":"Crossref","is-referenced-by-count":0,"title":["Atypical\n                    <i>Clostridioides difficile<\/i>\n                    Infection: Defining a Mortality-Associated Dysmotility Phenotype"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9391-1561","authenticated-orcid":false,"given":"Chin-Shiang","family":"Tsai","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University , Tainan ,","place":["Taiwan"]},{"name":"Division of Infectious Diseases & International Health, Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5951-3156","authenticated-orcid":false,"given":"Gregory R","family":"Madden","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases & International Health, Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"2026102116254038100_ciag603-B1","doi-asserted-by":"publisher","first-page":"ciag463","DOI":"10.1093\/cid\/ciag463","article-title":"A new paradigm for Clostridioides difficile infection: atypical presentations correlating to acute gastrointestinal dysmotility are associated with increased mortality","author":"Bishop","year":"2026","journal-title":"Clin Infect Dis"},{"key":"2026102116254038100_ciag603-B2","doi-asserted-by":"publisher","first-page":"ciag464","DOI":"10.1093\/cid\/ciag464","article-title":"Difficult diagnosis: C. difficile without diarrhea","author":"Petri","year":"2026","journal-title":"Clin Infect Dis"},{"key":"2026102116254038100_ciag603-B3","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cix1085","article-title":"Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)","volume":"66","author":"McDonald","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2026102116254038100_ciag603-B4","doi-asserted-by":"crossref","first-page":"105244","DOI":"10.1016\/j.ebiom.2024.105244","article-title":"Predicting Clostridioides difficile infection outcomes with explainable machine learning","volume":"106","author":"Madden","year":"2024","journal-title":"eBioMedicine"},{"key":"2026102116254038100_ciag603-B5","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-026-00871-z","article-title":"Propensity-matched case control study of anti-interleukin-23 therapies in Clostridioides difficile infection","author":"Madden","year":"2026","journal-title":"Gut Pathog"},{"key":"2026102116254038100_ciag603-B6","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1471-2334-13-148","article-title":"Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy","volume":"13","author":"Miller","year":"2013","journal-title":"BMC Infect Dis"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciag603\/71392726\/ciag603.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciag603\/71392726\/ciag603.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:25:51Z","timestamp":1792614351000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciag603\/8835415"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":6,"URL":"https:\/\/doi.org\/10.1093\/cid\/ciag603","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"article-number":"ciag603"}}