{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:43:14Z","timestamp":1790674994949,"version":"4.1.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,4,15]]},"DOI":"10.1093\/cid\/ciu066","type":"journal-article","created":{"date-parts":[[2014,2,8]],"date-time":"2014-02-08T05:24:14Z","timestamp":1391837054000},"page":"1064-1071","source":"Crossref","is-referenced-by-count":39,"title":["Effectiveness and Cost-effectiveness of Immediate Versus Delayed Treatment of Hepatitis C Virus\u2013Infected Patients in a Country With Limited Resources: The Case of Egypt"],"prefix":"10.1093","volume":"58","author":[{"given":"Doroth\u00e9e","family":"Obach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Deuffic-Burban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamal","family":"Esmat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wagida A.","family":"Anwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Dewedar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Canva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Cousien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wahid","family":"Doss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Mostafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Pol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Buti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Siebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Fontanet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa K.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazdan","family":"Yazdanpanah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,2,7]]},"reference":[{"key":"key\n\t\t\t\t20170522093223_CIU066C1","article-title":"Egypt demographic and health survey 2008","author":"El-Zanaty","year":"2009"},{"key":"key\n\t\t\t\t20170522093223_CIU066C2","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1002\/jmv.21492","article-title":"Genetic variability of hepatitis C virus in south Egypt and its possible clinical implication","volume":"81","author":"Elkady","year":"2009","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C3","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/S0140-6736(99)06527-7","article-title":"The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt","volume":"355","author":"Frank","year":"2000","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170522093223_CIU066C4","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1086\/315786","article-title":"Genetic epidemiology of hepatitis C virus throughout Egypt","volume":"182","author":"Ray","year":"2000","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170522093223_CIU066C5","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1093\/cid\/cis227","article-title":"Expanding access to treatment for hepatitis C in resource-limited settings: lessons from HIV\/AIDS","volume":"54","author":"Ford","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20170522093223_CIU066C6","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1002\/jmv.20679","article-title":"HCV-related morbidity in a rural community of Egypt","volume":"78","author":"Mohamed","year":"2006","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C7","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1001\/jama.1996.03540160061034","article-title":"Recommendations for reporting cost-effectiveness analyses. Panel on Cost-Effectiveness in Health and Medicine","volume":"276","author":"Siegel","year":"1996","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20170522093223_CIU066C8","article-title":"Making choices in health: WHO guide to cost-effectiveness analysis","author":"Tan-Torres Edejer","year":"2003"},{"key":"key\n\t\t\t\t20170522093223_CIU066C9","author":"World Bank. World development indicators for Egypt"},{"key":"key\n\t\t\t\t20170522093223_CIU066C10","doi-asserted-by":"crossref","first-page":"e358","DOI":"10.1111\/j.1365-2893.2010.01433.x","article-title":"Reproducibility of liver stiffness measurements in hepatitis C virus (HCV)-infected patients in Egypt","volume":"18","author":"Vignier","year":"2011","journal-title":"J Viral Hepat"},{"key":"key\n\t\t\t\t20170522093223_CIU066C11","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1002\/jmv.21570","article-title":"Response to pegylated interferon alfa-2a and ribavirin in chronic hepatitis C genotype 4","volume":"81","author":"El Makhzangy","year":"2009","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C12","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/j.1478-3231.2008.01750.x","article-title":"Predictors of a sustained virological response in patients with genotype 4 chronic hepatitis C","volume":"28","author":"Gad","year":"2008","journal-title":"Liver Int"},{"key":"key\n\t\t\t\t20170522093223_CIU066C13","article-title":"Le d\u00e9cideur public face \u00e0 la soci\u00e9t\u00e9 en micro\u00e9conomie de la sant\u00e9? Faisabilit\u00e9 et implications des strat\u00e9gies de valorisations en sant\u00e9 en France et en Egypte","author":"Schwarzinger","year":"2008"},{"key":"key\n\t\t\t\t20170522093223_CIU066C14","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1111\/j.1572-0241.2003.07332.x","article-title":"Health-state utilities and quality of life in hepatitis C patients","volume":"98","author":"Chong","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2165\/00019053-200927040-00006","article-title":"Clinical effectiveness and cost effectiveness of tailoring chronic hepatitis C treatment with peginterferon alpha-2b plus ribavirin to HCV genotype and early viral response: a decision analysis based on German guidelines","volume":"27","author":"Siebert","year":"2009","journal-title":"Pharmacoeconomics"},{"key":"key\n\t\t\t\t20170522093223_CIU066C16","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1056\/NEJMoa1214853","article-title":"Sofosbuvir for previously untreated chronic hepatitis C infection","volume":"368","author":"Lawitz","year":"2013","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170522093223_CIU066C17","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jhep.2005.10.013","article-title":"Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies","volume":"44","author":"D'Amico","year":"2006","journal-title":"J Hepatol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C18","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1053\/j.gastro.2009.09.067","article-title":"Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression","volume":"138","author":"Davis","year":"2010","journal-title":"Gastroenterology"},{"key":"key\n\t\t\t\t20170522093223_CIU066C19","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/hep.22375","article-title":"Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression","volume":"48","author":"Thein","year":"2008","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t20170522093223_CIU066C20","author":"United Nations Statistics. Demographic yearbook"},{"key":"key\n\t\t\t\t20170522093223_CIU066C21","author":"World Health Organization. Global Health Observatory Data Repository"},{"key":"key\n\t\t\t\t20170522093223_CIU066C22","article-title":"BMS-790052, a NS5A replication complex inhibitor, combined with peginterferon alfa 2a and ribavirin in treatment-naive HCV genotype 1 or 4 patients: phase 2b. AI444010 Study interim week 12 results","author":"Hezode","year":"2011"},{"key":"key\n\t\t\t\t20170522093223_CIU066C23","article-title":"The hepatitis C treatment pipeline report","author":"Swan","year":"2011"},{"key":"key\n\t\t\t\t20170522093223_CIU066C24","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.cgh.2009.11.018","article-title":"A sustained viral response is associated with reduced liver-related morbidity and mortality in patients with hepatitis C virus","volume":"8","author":"Singal","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C25","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/hep.23744","article-title":"Outcome of sustained virological responders with histologically advanced chronic hepatitis C","volume":"52","author":"Morgan","year":"2010","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t20170522093223_CIU066C26","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S1665-2681(19)31002-6","article-title":"Impact of sustained virologic response on quality of life in chronic HVC carriers","volume":"12","author":"Daltro-Oliveira","year":"2013","journal-title":"Ann Hepatol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C27","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S1665-2681(19)31410-3","article-title":"Validation and comparison of simple noninvasive models for the prediction of liver fibrosis in chronic hepatitis C","volume":"11","author":"Amorim","year":"2012","journal-title":"Ann Hepatol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C28","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1053\/jhep.2003.50346","article-title":"A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C","volume":"38","author":"Wai","year":"2003","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t20170522093223_CIU066C29","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/hep.21669","article-title":"FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest","volume":"46","author":"Vallet-Pichard","year":"2007","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t20170522093223_CIU066C30","doi-asserted-by":"crossref","first-page":"e22309","DOI":"10.1371\/journal.pone.0022309","article-title":"Optimal control of hepatitis C antiviral treatment programme delivery for prevention amongst a population of injecting drug users","volume":"6","author":"Martin","year":"2011","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170522093223_CIU066C31","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.jhep.2010.08.029","article-title":"Can antiviral therapy for hepatitis C reduce the prevalence of HCV among injecting drug user populations? A modeling analysis of its prevention utility","volume":"54","author":"Martin","year":"2011","journal-title":"J Hepatol"},{"key":"key\n\t\t\t\t20170522093223_CIU066C32","doi-asserted-by":"crossref","first-page":"e34548","DOI":"10.1371\/journal.pone.0034548","article-title":"Treatment of hepatitis C as prevention: a modeling case study in Vietnam","volume":"7","author":"Durier","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170522093223_CIU066C33","doi-asserted-by":"crossref","DOI":"10.1016\/S0168-8278(13)60055-0","article-title":"Impact of mass antiviral treatment on HCV transmission in rural Egypt","author":"Breban","year":"2013"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/58\/8\/1064\/17351927\/ciu066.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T13:09:02Z","timestamp":1565183342000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article-lookup\/doi\/10.1093\/cid\/ciu066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,7]]},"references-count":33,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2014,2,7]]},"published-print":{"date-parts":[[2014,4,15]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciu066","relation":{},"ISSN":["1537-6591","1058-4838"],"issn-type":[{"value":"1537-6591","type":"electronic"},{"value":"1058-4838","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2,7]]}}}