{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T02:03:32Z","timestamp":1778724212376,"version":"3.51.4"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"suppl_5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,11,15]]},"DOI":"10.1093\/cid\/civ598","type":"journal-article","created":{"date-parts":[[2015,11,9]],"date-time":"2015-11-09T19:33:10Z","timestamp":1447097590000},"page":"S422-S427","source":"Crossref","is-referenced-by-count":9,"title":["Ethical Challenges and Lessons Learned During the Clinical Development of a Group A Meningococcal Conjugate Vaccine"],"prefix":"10.1093","volume":"61","author":[{"given":"Lionel","family":"Martellet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samba O.","family":"Sow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldiouma","family":"Diallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham","family":"Hodgson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate","family":"Kampmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siddhivinayak","family":"Hirve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milagritos","family":"Tapia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadima Cheick","family":"Haidara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assane","family":"Ndiaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bou","family":"Diarra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick Odum","family":"Ansah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adebayo","family":"Akinsola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olubukola T.","family":"Idoko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard A.","family":"Adegbola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Bavdekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Juvekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simonetta","family":"Viviani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Godwin C.","family":"Enwere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Marchetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Chaumont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Francoise","family":"Makadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flore","family":"Pallardy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasad S.","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Pierre","family":"Preziosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. Marc","family":"LaForce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,11,9]]},"reference":[{"key":"key\n\t\t\t\t20171013233411_CIV598C1","doi-asserted-by":"crossref","first-page":"6859","DOI":"10.1016\/j.vaccine.2012.09.008","article-title":"Conducting vaccine clinical trials in sub-Saharan Africa: operational challenges and lessons learned from the Meningitis Vaccine Project","volume":"30","year":"2012","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20171013233411_CIV598C2","article-title":"Efficacy guidelines on Good Clinical Practices (E6), May 1996","author":"International Conference on Harmonisation (ICH)"},{"key":"key\n\t\t\t\t20171013233411_CIV598C3","article-title":"International ethical guidelines for epidemiological studies","author":"Council for International Organizations of Medical Sciences (CIOMS); World Health Organization (WHO)","year":"2009"},{"key":"key\n\t\t\t\t20171013233411_CIV598C4","article-title":"\u201cDeclaration of Helsinki\u201d adopted by the 18th WMA General Assembly, Helsinki, Finland, June 1964","author":"World Medical Association (WMA)"},{"key":"key\n\t\t\t\t20171013233411_CIV598C5","first-page":"S416","article-title":"Community perspectives associated with the African PsA-TT (MenAfriVac) vaccine trials","volume-title":"Clin Infect Dis","year":"2015"},{"key":"key\n\t\t\t\t20171013233411_CIV598C6","first-page":"771","article-title":"Beyond informed consent","volume":"82","year":"2004","journal-title":"Bull World Health Organ"},{"key":"key\n\t\t\t\t20171013233411_CIV598C7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1472-6939-11-3","article-title":"Convergent ethical issues in HIV\/AIDS, tuberculosis and malaria vaccine trials in Africa: report from the WHO\/UNAIDS African AIDS Vaccine Programme's Ethics, Law and Human Rights Collaborating Centre consultation, 10\u201311 February 2009, Durban, South Africa","volume":"11","year":"2010","journal-title":"BMC Med Ethics"},{"key":"key\n\t\t\t\t20171013233411_CIV598C8","first-page":"315","article-title":"Conducting research with human subjects in international settings: ethical considerations","volume":"86","year":"2013","journal-title":"Yale J Biol Med"},{"key":"key\n\t\t\t\t20171013233411_CIV598C9","first-page":"1","article-title":"Contextualizing the informed consent process in vaccine trials in developing countries","volume":"4","year":"2013","journal-title":"J Clinic Res Bioeth"},{"key":"key\n\t\t\t\t20171013233411_CIV598C10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1472-6939-12-3","article-title":"How participatory is parental consent in low literacy rural settings in low income countries? Lessons learned from a community based study of infants in South India","volume":"12","year":"2011","journal-title":"BMC Med Ethics"},{"key":"key\n\t\t\t\t20171013233411_CIV598C11","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/B978-0-444-53501-6.00025-1","article-title":"The ethics of clinical research in low- and middle-income countries","volume":"118","year":"2013","journal-title":"Handb Clin Neurol"},{"key":"key\n\t\t\t\t20171013233411_CIV598C12","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1472-6939-14-29","article-title":"Ethical challenges in integrating patient-care with clinical research in a resource-limited setting: perspectives from Papua New Guinea","volume":"14","year":"2013","journal-title":"BMC Med Ethics"},{"key":"key\n\t\t\t\t20171013233411_CIV598C13","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1353\/ken.2011.0019","article-title":"Health researchers\u2019 ancillary care obligations in low-resource settings: how can we tell what is morally required?","volume":"21","year":"2011","journal-title":"Kennedy Inst Ethics J"},{"key":"key\n\t\t\t\t20171013233411_CIV598C14","article-title":"Ethical considerations in HIV preventive vaccine research, guidance document","author":"Joint United Nations Programme on HIV\/AIDS","year":"2004","edition":"3rd ed"},{"key":"key\n\t\t\t\t20171013233411_CIV598C15","doi-asserted-by":"crossref","first-page":"4863","DOI":"10.1016\/j.vaccine.2007.03.022","article-title":"Ethical considerations related to the provision of care and treatment in vaccine trials","volume":"25","year":"2007","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20171013233411_CIV598C16","article-title":"International ethical guidelines for biomedical research involving human subjects prepared by the Council for International Organizations of Medical Sciences (CIOMS) in collaboration with the World Health Organization (WHO)","author":"Council for International Organizations of Medical Sciences (CIOMS)"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/61\/suppl_5\/S422\/20914382\/civ598.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T23:34:14Z","timestamp":1507937654000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/cid\/article\/61\/suppl_5\/S422\/418347\/Ethical-Challenges-and-Lessons-Learned-During-the"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,9]]},"references-count":16,"journal-issue":{"issue":"suppl_5","published-online":{"date-parts":[[2015,11,9]]},"published-print":{"date-parts":[[2015,11,15]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/civ598","relation":{},"ISSN":["1537-6591","1058-4838"],"issn-type":[{"value":"1537-6591","type":"electronic"},{"value":"1058-4838","type":"print"}],"subject":[],"published-other":{"date-parts":[[2015,11,15]]},"published":{"date-parts":[[2015,11,9]]}}}