{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:18:46Z","timestamp":1782602326369,"version":"3.54.5"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","funder":[{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000098","name":"Clinical Center","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NIH"},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Infect Dis."],"published-print":{"date-parts":[[2016,2,1]]},"DOI":"10.1093\/cid\/civ874","type":"journal-article","created":{"date-parts":[[2015,10,31]],"date-time":"2015-10-31T20:28:10Z","timestamp":1446323290000},"page":"280-288","source":"Crossref","is-referenced-by-count":45,"title":["Successful Retreatment of Chronic HCV Genotype-1 Infection With Ledipasvir and Sofosbuvir After Initial Short Course Therapy With Direct-Acting Antiviral Regimens"],"prefix":"10.1093","volume":"62","author":[{"given":"Eleanor M.","family":"Wilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Kattakuzhy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreetha","family":"Sidharthan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zayani","family":"Sims","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"McLaughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angie","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Silk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Gross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Akoth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Mo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Mani","family":"Subramanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip S.","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"McHutchison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Osinusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Masur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Kohli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam","family":"Kottilil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,10,31]]},"reference":[{"key":"2016010823122837000_62.3.280.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1316366"},{"key":"2016010823122837000_62.3.280.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402454"},{"key":"2016010823122837000_62.3.280.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402338"},{"key":"2016010823122837000_62.3.280.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402869"},{"key":"2016010823122837000_62.3.280.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402355"},{"key":"2016010823122837000_62.3.280.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61228-9"},{"issue":"S2","key":"2016010823122837000_62.3.280.7","doi-asserted-by":"crossref","first-page":"S669","DOI":"10.1016\/S0168-8278(15)31077-1","article-title":"Predictors of sustained viral response to 4\u20136 week duration therapy with ledipasvir + sofosbuvir + GS-9451 +\/\u2212 GS-9669 in early and advanced fibrosis (NIH\/UMD synergy trial)","volume":"62","author":"Kattakuzhy","year":"2015","journal-title":"J Hepatology"},{"key":"2016010823122837000_62.3.280.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)70050-2"},{"key":"2016010823122837000_62.3.280.9","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27890"},{"key":"2016010823122837000_62.3.280.10","doi-asserted-by":"publisher","DOI":"10.7326\/M14-1211"},{"issue":"S2","key":"2016010823122837000_62.3.280.11","doi-asserted-by":"crossref","first-page":"S192","DOI":"10.1016\/S0168-8278(15)30012-X","article-title":"Retreatment of patients who failed 8 or 12 weeks of ledipasvir\/sofosbuvir-based regimens with ledipasvir\/sofosbuvir for 24 weeks","volume":"62","author":"Lawitz","year":"2015","journal-title":"J Hepatology"},{"issue":"S2","key":"2016010823122837000_62.3.280.12","doi-asserted-by":"crossref","first-page":"S221","DOI":"10.1016\/S0168-8278(15)30073-8","article-title":"Long-term persistence of HCV NS5A variants after treatment with NS5A inhibitor ledipasvir","volume":"62","author":"Dvory-Sobol","year":"2015","journal-title":"J Hepatology"},{"issue":"S2","key":"2016010823122837000_62.3.280.13","doi-asserted-by":"crossref","first-page":"S220","DOI":"10.1016\/S0168-8278(15)30071-4","article-title":"Long-term follow-up of treatment-emergent resistance-associated variants in NS3, NS5A and NS5B with paritaprevir\/r-, ombitasvir- and dasabuvir-based regimens","volume":"62","author":"Krishnan","year":"2015","journal-title":"J Hepatology"},{"key":"2016010823122837000_62.3.280.14","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-10-40"},{"key":"2016010823122837000_62.3.280.15","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24105"},{"key":"2016010823122837000_62.3.280.16","unstructured":"U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 1.0. [Updated August 2009]. Available at: http:\/\/rsc.tech-res.com\/Document\/safetyandpharmacovigilance\/Table_for_Grading_Severity_of_Adult_Pediatric_Adverse_Events.pdf. Accessed 19 October 2015."},{"key":"2016010823122837000_62.3.280.17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.109309"},{"key":"2016010823122837000_62.3.280.18","doi-asserted-by":"crossref","unstructured":"Lontok E , Harrington P , Howe A et al . Hepatitis C virus drugs resistance-associated substitutions: state of the art summary. Hepatology 2015; doi:10.1002\/hep.27934.","DOI":"10.1002\/hep.27934"},{"key":"2016010823122837000_62.3.280.19","unstructured":"Kohli A , Kattakuzhy S , Sidharthan S et al . Four-week directly acting anti-HCV regimens in HCV genotype-1 patients without cirrhosis: a phase 2a cohort study. Ann Intern Med 2015; in press."},{"key":"2016010823122837000_62.3.280.20","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/cid\/civ897","article-title":"Six-week combination directly acting anti-HCV therapy induces moderate rates of sustained virologic response in patients with advanced liver disease","volume":"62","author":"Kattakuzhy","year":"2016","journal-title":"Clin Infect Dis"},{"key":"2016010823122837000_62.3.280.21","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02193-12"},{"key":"2016010823122837000_62.3.280.22","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(12)61184-2"},{"key":"2016010823122837000_62.3.280.23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122844"},{"key":"2016010823122837000_62.3.280.24","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu697"},{"key":"2016010823122837000_62.3.280.25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1208953"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/62\/3\/280\/16789353\/civ874.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T03:50:29Z","timestamp":1748663429000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article-lookup\/doi\/10.1093\/cid\/civ874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,31]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,1,8]]},"published-print":{"date-parts":[[2016,2,1]]}},"alternative-id":["10.1093\/cid\/civ874"],"URL":"https:\/\/doi.org\/10.1093\/cid\/civ874","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.725898672.793511188","asserted-by":"object"}]},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,31]]}}}