{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T12:27:53Z","timestamp":1777638473683,"version":"3.51.4"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"11","funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Infect Dis."],"published-print":{"date-parts":[[2016,12,1]]},"DOI":"10.1093\/cid\/ciw580","type":"journal-article","created":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T20:18:20Z","timestamp":1471983500000},"page":"1405-1411","source":"Crossref","is-referenced-by-count":88,"title":["Efficacy and Safety of Ledipasvir\/Sofosbuvir With and Without Ribavirin in Patients With Chronic HCV Genotype 1 Infection Receiving Opioid Substitution Therapy: Analysis of Phase 3 ION Trials"],"prefix":"10.1093","volume":"63","author":[{"given":"Jason","family":"Grebely","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Mauss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Pierre","family":"Bronowicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Puoti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Wyles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Macky","family":"Natha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanni","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Kreter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana M.","family":"Brainard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chohee","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val","family":"Carr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory J.","family":"Dore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,8,23]]},"reference":[{"key":"2016111201323375000_63.11.1405.1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.107"},{"key":"2016111201323375000_63.11.1405.2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu643"},{"key":"2016111201323375000_63.11.1405.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2012.03803.x"},{"key":"2016111201323375000_63.11.1405.4","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit300"},{"key":"2016111201323375000_63.11.1405.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2015.07.005"},{"key":"2016111201323375000_63.11.1405.6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26431"},{"key":"2016111201323375000_63.11.1405.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2015.07.010"},{"key":"2016111201323375000_63.11.1405.8","doi-asserted-by":"publisher","DOI":"10.1086\/600304"},{"key":"2016111201323375000_63.11.1405.9","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit306"},{"key":"2016111201323375000_63.11.1405.10","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis1007"},{"key":"2016111201323375000_63.11.1405.11","doi-asserted-by":"publisher","DOI":"10.7326\/M15-0406"},{"key":"2016111201323375000_63.11.1405.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2011.02.023"},{"key":"2016111201323375000_63.11.1405.13","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit302"},{"key":"2016111201323375000_63.11.1405.14","unstructured":"AASLD\/IDSA. Recommendations for testing, managing, and treating hepatitis C. Available at: www.hcvguidelines.org . Accessed 18 January."},{"key":"2016111201323375000_63.11.1405.15","unstructured":"WHO. Guidelines for the screening, care and treatment of persons with hepatitis C infection. Geneva, Switzerland: World Health Organization, 2014."},{"key":"2016111201323375000_63.11.1405.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.02.007"},{"key":"2016111201323375000_63.11.1405.17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402454"},{"key":"2016111201323375000_63.11.1405.18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1316366"},{"key":"2016111201323375000_63.11.1405.19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402355"},{"key":"2016111201323375000_63.11.1405.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.10.033"},{"key":"2016111201323375000_63.11.1405.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.03.029"},{"key":"2016111201323375000_63.11.1405.22","doi-asserted-by":"crossref","unstructured":"Dore GJ , Altice F , Litwin AH et al . Elbasvir\/grazoprevir to treat HCV infection in persons receiving opioid agonist therapy: a randomized controlled trial (C-EDGE CO-STAR). Ann Intern Med 2016; doi:10.7326\/M16-0816 .","DOI":"10.7326\/M16-0816"},{"key":"2016111201323375000_63.11.1405.23","unstructured":"4th International Symposium on Hepatitis Care in Substance Users, Sydney, Australia, 7-9 October 2016."},{"key":"2016111201323375000_63.11.1405.24","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ948"},{"key":"2016111201323375000_63.11.1405.25","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.36"},{"key":"2016111201323375000_63.11.1405.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.06.014"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cid\/article\/63\/11\/1405\/2526223\/Efficacy-and-Safety-of-LedipasvirSofosbuvir-With","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T17:14:32Z","timestamp":1498324472000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article-lookup\/doi\/10.1093\/cid\/ciw580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,23]]},"references-count":26,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2016,11,12]]},"published-print":{"date-parts":[[2016,12,1]]}},"alternative-id":["10.1093\/cid\/ciw580"],"URL":"https:\/\/doi.org\/10.1093\/cid\/ciw580","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,23]]}}}