{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:00:32Z","timestamp":1787752832875,"version":"build-2784847793"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T00:00:00Z","timestamp":1519689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["2R01HD061959-07A2"],"award-info":[{"award-number":["2R01HD061959-07A2"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"crossref","award":["2013\/06579-0"],"award-info":[{"award-number":["2013\/06579-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,8,16]]},"DOI":"10.1093\/cid\/ciy166","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T20:17:33Z","timestamp":1519676253000},"page":"743-750","source":"Crossref","is-referenced-by-count":56,"title":["Cytomegalovirus Shedding in Seropositive Pregnant Women From a High-Seroprevalence Population: The Brazilian Cytomegalovirus Hearing and Maternal Secondary Infection Study"],"prefix":"10.1093","volume":"67","author":[{"given":"Nayara G","family":"Barbosa","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparecida Y","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldo","family":"Duarte","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davi C","family":"Aragon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen B","family":"Fowler","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Boppana","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J","family":"Britt","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa M","family":"Mussi-Pinhata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,2,27]]},"reference":[{"key":"key\n\t\t\t\t20180816010357_CIT0001","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1128\/CMR.00062-12","article-title":"The \u201csilent\u201d global burden of congenital cytomegalovirus","volume":"26","author":"Manicklal","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"key\n\t\t\t\t20180816010357_CIT0002","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1017\/S0950268812002695","article-title":"Early high CMV seroprevalence in pregnant women from a population with a high rate of congenital infection","volume":"141","author":"Yamamoto","year":"2013","journal-title":"Epidemiol Infect"},{"key":"key\n\t\t\t\t20180816010357_CIT0003","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00430-015-0399-9","article-title":"Controversies in the natural history of congenital human cytomegalovirus infection: the paradox of infection and disease in offspring of women with immunity prior to pregnancy","volume":"204","author":"Britt","year":"2015","journal-title":"Med Microbiol Immunol"},{"key":"key\n\t\t\t\t20180816010357_CIT0004","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1086\/600882","article-title":"Birth prevalence and natural history of congenital cytomegalovirus infection in a highly seroimmune population","volume":"49","author":"Mussi-Pinhata","year":"2009","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0005","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1056\/NEJM200105033441804","article-title":"Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity","volume":"344","author":"Boppana","year":"2001","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180816010357_CIT0006","doi-asserted-by":"crossref","first-page":"297 e1","DOI":"10.1016\/j.ajog.2009.11.018","article-title":"Human cytomegalovirus reinfection is associated with intrauterine transmission in a highly cytomegalovirus-immune maternal population","volume":"202","author":"Yamamoto","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20180816010357_CIT0007","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/rmv.695","article-title":"Review of cytomegalovirus shedding in bodily fluids and relevance to congenital cytomegalovirus infection","volume":"21","author":"Cannon","year":"2011","journal-title":"Rev Med Virol"},{"key":"key\n\t\t\t\t20180816010357_CIT0008","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.clp.2016.11.012","article-title":"Postnatal cytomegalovirus infection through human milk in preterm infants: transmission, clinical presentation, and prevention","volume":"44","author":"Hamprecht","year":"2017","journal-title":"Clin Perinatol"},{"key":"key\n\t\t\t\t20180816010357_CIT0009","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1128\/JCM.31.6.1635-1636.1993","article-title":"Cytomegalovirus excretion in pregnant and nonpregnant women","volume":"31","author":"Shen","year":"1993","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180816010357_CIT0010","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/infdis\/131.5.522","article-title":"Cervical cytomegalovirus excretion in pregnant and nonpregnant women: suppression in early gestation","volume":"131","author":"Stagno","year":"1975","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0011","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/infdis\/152.2.249","article-title":"Epidemiology of cytomegaloviral infection in a heterogeneous population of pregnant women","volume":"152","author":"Chandler","year":"1985","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0012","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1086\/657412","article-title":"Cytomegalovirus viruria and DNAemia in healthy seropositive women","volume":"202","author":"Arora","year":"2010","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0013","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1128\/JCM.01079-07","article-title":"Cytomegalovirus strain diversity in seropositive women","volume":"46","author":"Novak","year":"2008","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180816010357_CIT0014","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1086\/497150","article-title":"Association between genital tract cytomegalovirus infection and bacterial vaginosis","volume":"192","author":"Ross","year":"2005","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0015","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1590\/S0037-86821998000100003","article-title":"Diagnosis of congenital and perinatal infection by cytomegalovirus using polymerase chain reaction [in Portugese]","volume":"31","author":"Yamamoto","year":"1998","journal-title":"Rev Soc Bras Med Trop"},{"key":"key\n\t\t\t\t20180816010357_CIT0016","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/jmv.20619","article-title":"Screening for vaginal shedding of cytomegalovirus in healthy pregnant women using real-time PCR: correlation of CMV in the vagina and adverse outcome of pregnancy","volume":"78","author":"Tanaka","year":"2006","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20180816010357_CIT0017","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1086\/314939","article-title":"Asymptomatic primary cytomegalovirus infection: virologic and immunologic features","volume":"180","author":"Zanghellini","year":"1999","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0018","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/infdis\/140.3.419","article-title":"Comparative prevalence of subclinical cytomegalovirus and herpes simplex virus infections in the genital and urinary tracts of low-income, urban women","volume":"140","author":"Knox","year":"1979","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0019","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF01341724","article-title":"A comparison of cervical cytomegalovirus (CMV) excretion in gynaecological patients and post-partum women","volume":"73","author":"Knowles","year":"1982","journal-title":"Arch Virol"},{"key":"key\n\t\t\t\t20180816010357_CIT0020","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/infdis\/171.1.33","article-title":"Cervical but not urinary excretion of cytomegalovirus is related to sexual activity and contraceptive practices in sexually active women","volume":"171","author":"Collier","year":"1995","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0021","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/jmv.1890450212","article-title":"Cytomegalovirus infection and viral shedding in the genital tract of infertile couples","volume":"45","author":"Yang","year":"1995","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20180816010357_CIT0022","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1186\/s12879-014-0568-2","article-title":"Cross-sectional study of cytomegalovirus shedding and immunological markers among seropositive children and their mothers","volume":"14","author":"Stowell","year":"2014","journal-title":"BMC Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0023","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/infdis\/jiw076","article-title":"Prospective characterization of the risk factors for transmission and symptoms of primary human herpesvirus infections among Ugandan infants","volume":"214","author":"Gantt","year":"2016","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0024","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/aogs.12134","article-title":"Frequent detection of cytomegalovirus and Epstein-Barr virus in cervical secretions from healthy young women","volume":"92","author":"Berntsson","year":"2013","journal-title":"Acta Obstet Gynecol Scand"},{"key":"key\n\t\t\t\t20180816010357_CIT0025","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1128\/JCM.02206-10","article-title":"Shedding of Epstein-Barr virus and cytomegalovirus from the genital tract of women in a periurban community in Andhra Pradesh, India","volume":"49","author":"Silver","year":"2011","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180816010357_CIT0026","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1542\/peds.49.4.524","article-title":"Recovery of cytomegalovirus from the cervix in pregnancy","volume":"49","author":"Montgomery","year":"1972","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20180816010357_CIT0027","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1002\/jmv.24158","article-title":"Study of human cytomegalovirus replication in body fluids, placental infection, and miscarriage during the first trimester of pregnancy","volume":"87","author":"Yan","year":"2015","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20180816010357_CIT0028","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1086\/586715","article-title":"Virological and immunological correlates of mother-to-child transmission of cytomegalovirus in The Gambia","volume":"197","author":"Kaye","year":"2008","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0029","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jcv.2014.10.002","article-title":"Cytomegalovirus DNAemia in pregnant women","volume":"61","author":"Revello","year":"2014","journal-title":"J Clin Virol"},{"key":"key\n\t\t\t\t20180816010357_CIT0030","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1099\/jmm.0.027771-0","article-title":"Cytomegalovirus (CMV) shedding is highly correlated with markers of immunosuppression in CMV-seropositive women","volume":"60","author":"Schoenfisch","year":"2011","journal-title":"J Med Microbiol"},{"key":"key\n\t\t\t\t20180816010357_CIT0031","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ypmed.2012.03.009","article-title":"Awareness of and behaviors related to child-to-mother transmission of cytomegalovirus","volume":"54","author":"Cannon","year":"2012","journal-title":"Prev Med"},{"key":"key\n\t\t\t\t20180816010357_CIT0032","doi-asserted-by":"crossref","first-page":"e286","DOI":"10.1542\/peds.2005-1142","article-title":"Risk factors for congenital cytomegalovirus infection in the offspring of young women: exposure to young children and recent onset of sexual activity","volume":"118","author":"Fowler","year":"2006","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20180816010357_CIT0033","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1186\/s12879-014-0569-1","article-title":"Repeated measures study of weekly and daily cytomegalovirus shedding patterns in saliva and urine of healthy cytomegalovirus-seropositive children","volume":"14","author":"Cannon","year":"2014","journal-title":"BMC Infect Dis"},{"key":"key\n\t\t\t\t20180816010357_CIT0034","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1542\/peds.74.1.121","article-title":"Increased frequency of cytomegalovirus infection in children in group day care","volume":"74","author":"Pass","year":"1984","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20180816010357_CIT0035","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1056\/NEJM198605293142204","article-title":"Increased rate of cytomegalovirus infection among parents of children attending day-care centers","volume":"314","author":"Pass","year":"1986","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180816010357_CIT0036","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1056\/NEJM198911093211903","article-title":"Cytomegalovirus and child day care. Evidence for an increased infection rate among day-care workers","volume":"321","author":"Adler","year":"1989","journal-title":"N Engl J Med"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/67\/5\/743\/25496807\/ciy166.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,14]],"date-time":"2022-08-14T22:17:26Z","timestamp":1660515446000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/67\/5\/743\/4911485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,27]]},"references-count":36,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2018,2,27]]},"published-print":{"date-parts":[[2018,8,16]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciy166","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,9,1]]},"published":{"date-parts":[[2018,2,27]]}}}