{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:44:50Z","timestamp":1788925490778,"version":"build-2803163510"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T00:00:00Z","timestamp":1522022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI068634"],"award-info":[{"award-number":["UM1 AI068634"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI068636"],"award-info":[{"award-number":["UM1 AI068636"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI106701"],"award-info":[{"award-number":["UM1 AI106701"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069432"],"award-info":[{"award-number":["UM1 AI069432"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069494"],"award-info":[{"award-number":["UM1 AI069494"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UO1 AI068634"],"award-info":[{"award-number":["UO1 AI068634"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069471"],"award-info":[{"award-number":["UM1 AI069471"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069419"],"award-info":[{"award-number":["UM1 AI069419"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069511"],"award-info":[{"award-number":["UM1 AI069511"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069467"],"award-info":[{"award-number":["UM1 AI069467"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069534,"],"award-info":[{"award-number":["UM1 AI069534,"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI069418"],"award-info":[{"award-number":["UM1 AI069418"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004334","name":"Merck & Co, Inc,","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,11,13]]},"DOI":"10.1093\/cid\/ciy242","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T08:08:19Z","timestamp":1521878899000},"page":"1712-1719","source":"Crossref","is-referenced-by-count":29,"title":["Safety and Immunogenicity of Zoster Vaccine Live in Human Immunodeficiency Virus\u2013Infected Adults With CD4+ Cell Counts >200 Cells\/mL Virologically Suppressed on Antiretroviral Therapy"],"prefix":"10.1093","volume":"67","author":[{"given":"Constance A","family":"Benson","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, University of California, San Diego"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet W","family":"Andersen","sequence":"additional","affiliation":[{"name":"Statistical and Data Analysis Center, Harvard School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard J C","family":"Macatangay","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robbie B","family":"Mailliard","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Charles R","family":"Rinaldo","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Read","sequence":"additional","affiliation":[{"name":"Therapeutics Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIAID\/NIH), Rockville"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn R","family":"Bozzolo","sequence":"additional","affiliation":[{"name":"Social and Scientific Systems, Inc, Silver Spring"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette","family":"Purdue","sequence":"additional","affiliation":[{"name":"Pharmaceutical Affairs Branch, Division of AIDS, NIAID\/NIH, Rockville, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Jennings","sequence":"additional","affiliation":[{"name":"Clinical Retrovirology Research Laboratory, Rush University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C","family":"Keefer","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, University of Rochester, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marshall","family":"Glesby","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Weill Cornell Medical College, Cornell University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Tebas","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, University of Pennsylvania Perelman School of Medicine, Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy Falk","family":"Russell","sequence":"additional","affiliation":[{"name":"Clinical Research, Merck Research Laboratories, Merck & Co, Inc, Kenilworth, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Martin","sequence":"additional","affiliation":[{"name":"Biostatistics and Research Decision Sciences, Merck Research Laboratories, Merck & Co, Inc, Kenilworth, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Annunziato","sequence":"additional","affiliation":[{"name":"Clinical Research, Merck Research Laboratories, Merck & Co, Inc, Kenilworth, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran","family":"Popmihajlov","sequence":"additional","affiliation":[{"name":"Clinical Research, Merck Research Laboratories, Merck & Co, Inc, Kenilworth, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L","family":"Lennox","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Emory University, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,3,26]]},"reference":[{"key":"key\n\t\t\t\t2018111310155621200_CIT0001","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1056\/NEJM198312083092306","article-title":"Varicella and herpes zoster. Changing concepts of the natural history, control, and importance of a not-so-benign virus","volume":"309","author":"Weller","year":"1983","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0002","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1056\/NEJM199607043350107","article-title":"Postherpetic neuralgia\u2014pathogenesis, treatment, and prevention","volume":"335","author":"Kost","year":"1996","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0003","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1086\/368196","article-title":"Treatment and prevention of postherpetic neuralgia","volume":"36","author":"Dworkin","year":"2003","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0004","doi-asserted-by":"crossref","first-page":"375","DOI":"10.7326\/0003-4819-89-3-375","article-title":"NIH conference: HZ-varicella infections in immunosuppressed patients","volume":"89","author":"Dolin","year":"1978","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/infdis\/165.1.119","article-title":"Subclinical varicella-zoster virus viremia, herpes zoster, and T lymphocyte immunity to varicella-zoster viral antigens after bone marrow transplantation","volume":"165","author":"Wilson","year":"1992","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0006","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/QAI.0b013e318266cd3c","article-title":"Herpes zoster among persons living with HIV in the current antiretroviral therapy era","volume":"61","author":"Blank","year":"2012","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0007","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1086\/503903","article-title":"Immune reconstitution syndrome in HIV: validating a case definition and identifying clinical predictors in persons initiating antiretroviral therapy","volume":"42","author":"Robertson","year":"2006","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0008","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1086\/499356","article-title":"Incidence and risk factors for immune reconstitution inflammatory syndrome in an ethnically diverse HIV type 1-infected cohort","volume":"42","author":"Ratnam","year":"2006","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0009","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/01.qai.0000178408.62675.b0","article-title":"The incidence of, risk factors for, and sequelae of herpes zoster among HIV patients in the highly active antiretroviral therapy era","volume":"40","author":"Gebo","year":"2005","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0010","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1086\/379048","article-title":"Decline in varicella-zoster virus (VZV)-specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine","volume":"188","author":"Levin","year":"2003","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0011","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1056\/NEJMoa051016","article-title":"A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults","volume":"352","author":"Oxman","year":"2005","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0012","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/cid\/cir970","article-title":"Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50\u201359 years","volume":"54","author":"Schmader","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0013","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1086\/514077","article-title":"Early reconstitution of immunity and decreased severity of herpes zoster in bone marrow transplant recipients immunized with inactivated varicella vaccine","volume":"176","author":"Redman","year":"1997","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0014","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1056\/NEJMoa013441","article-title":"Use of an inactivated varicella vaccine in recipients of hematopoietic-cell transplants","volume":"347","author":"Hata","year":"2002","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0015","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1086\/505149","article-title":"Administration of live varicella vaccine to HIV-infected children with current or past significant depression of CD4(+) T cells","volume":"194","author":"Levin","year":"2006","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0016","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1056\/NEJMoa1501184","article-title":"Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults","volume":"372","author":"Lal","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0017","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1056\/NEJMoa1603800","article-title":"Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older","volume":"375","author":"Cunningham","year":"2016","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0018","author":"US Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0019","author":"International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0020","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1056\/NEJMoa031772","article-title":"Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection","volume":"350","author":"Gulick","year":"2004","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0021","first-page":"9","article-title":"The nature of herpes zoster: a long-term study and a new hypothesis","volume":"58","author":"Hope-Simpson","year":"1965","journal-title":"Proc R Soc Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0022","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/QAI.0b013e318266cd3c","article-title":"Herpes zoster among persons living with HIV in the current antiretroviral therapy era","volume":"61","author":"Blank","year":"2012","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0023","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1093\/infdis\/jiu279","article-title":"Fold rise in antibody titers by measured by glycoprotein-based enzyme-linked immunosorbent assay is an excellent correlate of protection for a herpes zoster vaccine, demonstrated via the vaccine efficacy curve","volume":"210","author":"Gilbert","year":"2014","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0024","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1093\/cid\/cis638","article-title":"Persistence of the efficacy of zoster vaccine in the shingles prevention study and the short-term persistence substudy","volume":"55","author":"Schmader","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0025","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1093\/infdis\/jit342","article-title":"Varicella-zoster virus-specific antibody responses in 50\u201359-year-old recipients of zoster vaccine","volume":"208","author":"Levin","year":"2013","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0026","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1093\/infdis\/jit344","article-title":"Safety and immunogenicity of heat-treated zoster vaccine (ZVHT) in immunocompromised adults","volume":"208","author":"Mullane","year":"2013","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0027","doi-asserted-by":"crossref","first-page":"318","DOI":"10.4161\/hv.6.4.10654","article-title":"Safety and immunogenicity of a live attenuated varicella vaccine in VZV-seropositive HIV-infected adults","volume":"6","author":"Weinberg","year":"2010","journal-title":"Hum Vaccin"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0028","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1093\/infdis\/jiu606","article-title":"Safety and immunogenicity of an adjuvanted herpes zoster subunit candidate vaccine in HIV-infected adults: a phase 1\/2a randomized, placebo-controlled study","volume":"211","author":"Berkowitz","year":"2015","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0029","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.vaccine.2011.11.096","article-title":"Safety, tolerability, and immunogenicity after 1 and 2 doses of zoster vaccine in healthy adults \u226560 years of age","volume":"30","author":"Vermeulen","year":"2012","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0030","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s11606-008-0558-4","article-title":"Live, attenuated varicella zoster vaccination of an immunocompromised patient","volume":"23","author":"Curtis","year":"2008","journal-title":"J Gen Intern Med"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0031","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2015-212688","article-title":"Fatal disseminated varicella zoster infection following zoster vaccination in an immunocompromised patient","author":"Costa","year":"2016","journal-title":"BMJ Case Rep"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0032","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.mayocp.2016.04.010","article-title":"Risk of disseminated disease in immunosuppressed patients receiving live zoster vaccine","volume":"91","author":"Young","year":"2016","journal-title":"Mayo Clin Proc"},{"key":"key\n\t\t\t\t2018111310155621200_CIT0033","doi-asserted-by":"crossref","first-page":"103","DOI":"10.15585\/mmwr.mm6703a5","article-title":"Recommendations of the Advisory Committee on Immunization Practices for use of herpes zoster vaccines","volume":"67","author":"Dooling","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/67\/11\/1712\/26554961\/ciy242.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T07:28:37Z","timestamp":1570951717000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/67\/11\/1712\/4953774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,26]]},"references-count":33,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,3,26]]},"published-print":{"date-parts":[[2018,11,13]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciy242","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,12,1]]},"published":{"date-parts":[[2018,3,26]]}}}