{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:25:01Z","timestamp":1787826301860,"version":"build-2784847793"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,5]]},"DOI":"10.1093\/cid\/ciy558","type":"journal-article","created":{"date-parts":[[2018,7,7]],"date-time":"2018-07-07T19:36:56Z","timestamp":1530992216000},"page":"913-918","source":"Crossref","is-referenced-by-count":107,"title":["Performance of Treponemal Tests for the Diagnosis of Syphilis"],"prefix":"10.1093","volume":"68","author":[{"given":"Ina U","family":"Park","sequence":"first","affiliation":[{"name":"Sexually Transmitted Disease Control Branch, Division of Communicable Disease Control, California Department of Public Health, Richmond"},{"name":"Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yetunde F","family":"Fakile","sequence":"additional","affiliation":[{"name":"Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan M","family":"Chow","sequence":"additional","affiliation":[{"name":"Sexually Transmitted Disease Control Branch, Division of Communicable Disease Control, California Department of Public Health, Richmond"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen J","family":"Gustafson","sequence":"additional","affiliation":[{"name":"Sexually Transmitted Disease Control Branch, Division of Communicable Disease Control, California Department of Public Health, Richmond"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Jost","sequence":"additional","affiliation":[{"name":"Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M","family":"Schapiro","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Northern California Regional Laboratory, Berkeley"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Novak-Weekley","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group Regional Reference Laboratory, North Hollywood"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Tran","sequence":"additional","affiliation":[{"name":"San Francisco Department of Public Health, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jim H","family":"Nomura","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Chen","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manie","family":"Beheshti","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Townson","family":"Tsai","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Hoover","sequence":"additional","affiliation":[{"name":"Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail","family":"Bolan","sequence":"additional","affiliation":[{"name":"Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,7,9]]},"reference":[{"key":"key\n\t\t\t\t2019030423555183200_CIT0001","volume-title":"Sexually transmitted disease surveillance 2016","year":"2017"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0002","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1097\/OLQ.0b013e3181124473","article-title":"An evaluation of the relative sensitivities of the Venereal Disease Research Laboratory test and the Treponema pallidum particle agglutination test among patients diagnosed with primary syphilis","volume":"34","author":"Creegan","year":"2007","journal-title":"Sex Transm Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0003","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/095646249500600404","article-title":"Are you sure it\u2019s syphilis? A review of false positive serology","volume":"6","author":"Nandwani","year":"1995","journal-title":"Int J STD AIDS"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0004","first-page":"1","article-title":"Sexually transmitted diseases treatment guidelines, 2015","volume":"64","author":"Workowski","year":"2015","journal-title":"MMWR Recomm Rep"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0005","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/OLQ.0000000000000126","article-title":"Evaluation of diagnostic serological results in cases of suspected primary syphilis infection","volume":"41","author":"Gratzer","year":"2014","journal-title":"Sex Transm Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0006","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1093\/infdis\/jir524","article-title":"Screening for syphilis with the treponemal immunoassay: analysis of discordant serology results and implications for clinical management","volume":"204","author":"Park","year":"2011","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0007","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/cid\/civ445","article-title":"Discordant syphilis immunoassays in pregnancy: perinatal outcomes and implications for clinical management","volume":"61","author":"Mmeje","year":"2015","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0008","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1093\/infdis\/jis459","article-title":"Significance of isolated reactive treponemal chemiluminescence immunoassay results","volume":"207","author":"Hunter","year":"2013","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0009","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/OLQ.0000000000000446","article-title":"The significance of isolated reactive treponemal enzyme immunoassay in the diagnosis of early syphilis","volume":"43","author":"Caswell","year":"2016","journal-title":"Sex Transm Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0010","first-page":"133","article-title":"Discordant results from reverse sequence syphilis screening\u2014five laboratories, United States, 2006\u20132010","volume":"60","year":"2011","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0011","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1258\/ijsa.2009.009026","article-title":"Comparative evaluation of the INNO-LIA syphilis score and the MarDx Treponema pallidum immunoglobulin G Marblot test assays for the serological diagnosis of syphilis","volume":"21","author":"Lam","year":"2010","journal-title":"Int J STD AIDS"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0012","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1128\/JCM.36.4.913-917.1998","article-title":"Novel recombinant-antigen enzyme immunoassay for serological diagnosis of syphilis","volume":"36","author":"Young","year":"1998","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0013"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0014","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01165-17","article-title":"Correlation of treponemal immunoassay signal strength values with reactivity of confirmatory treponemal testing","volume":"56","author":"Fakile","year":"2018","journal-title":"J Clin Micro"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0015","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1097\/00007435-199811000-00010","article-title":"Treponemal specific tests for the serodiagnosis of syphilis. Syphilis and HIV Study Group","volume":"25","author":"Augenbraun","year":"1998","journal-title":"Sex Transm Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0016","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1128\/JCM.28.8.1704-1707.1990","article-title":"Evaluation of the Captia enzyme immunoassays for detection of immunoglobulins G and M to Treponema pallidum in syphilis","volume":"28","author":"Lefevre","year":"1990","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0017","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/OLQ.0b013e318205491a","article-title":"Evaluation of an IgM\/IgG sensitive enzyme immunoassay and the utility of index values for the screening of syphilis infection in a high-risk population","volume":"38","author":"Wong","year":"2011","journal-title":"Sex Transm Dis"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0018","doi-asserted-by":"crossref","first-page":"523","DOI":"10.7754\/Clin.Lab.2012.120519","article-title":"Evaluation of a new recombinant antigen-based Virotech Treponema pallidum screen ELISA for diagnosis of syphilis","volume":"59","author":"Busse","year":"2013","journal-title":"Clin Lab"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0019","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1177\/0956462415621660","article-title":"The management of isolated positive syphilis enzyme immunoassay results in HIV-negative patients attending a sexual health clinic","volume":"27","author":"Thorley","year":"2016","journal-title":"Int J STD AIDS"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0020","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1001\/jama.2016.5824","article-title":"Screening for syphilis infection in nonpregnant adults and adolescents: US Preventive Services Task Force recommendation statement","volume":"315","author":"Bibbins-Domingo","year":"2016","journal-title":"JAMA"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0021","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.7326\/0003-4819-114-12-1005","article-title":"Serologic response to treatment of infectious syphilis","volume":"114","author":"Romanowski","year":"1991","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0022","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00002030-199104000-00010","article-title":"Specific syphilis serological tests may become negative in HIV infection","volume":"5","author":"Johnson","year":"1991","journal-title":"AIDS"},{"key":"key\n\t\t\t\t2019030423555183200_CIT0023","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1159\/000018149","article-title":"A prospective study of the influence of HIV status on the seroreversion of serological tests for syphilis","volume":"198","author":"Janier","year":"1999","journal-title":"Dermatology"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/68\/6\/913\/28009258\/ciy558.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T03:01:48Z","timestamp":1661569308000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/68\/6\/913\/5050740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,9]]},"references-count":23,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2018,7,9]]},"published-print":{"date-parts":[[2019,3,5]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciy558","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,3,15]]},"published":{"date-parts":[[2018,7,9]]}}}