{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:32:36Z","timestamp":1789619556330,"version":"build-2803163510"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2018,7,7]],"date-time":"2018-07-07T00:00:00Z","timestamp":1530921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["102807"],"award-info":[{"award-number":["102807"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,5]]},"DOI":"10.1093\/cid\/ciy574","type":"journal-article","created":{"date-parts":[[2018,7,7]],"date-time":"2018-07-07T01:57:34Z","timestamp":1530928654000},"page":"927-933","source":"Crossref","is-referenced-by-count":65,"title":["Randomized Trial of Community Treatment With Azithromycin and Ivermectin Mass Drug Administration for Control of Scabies and Impetigo"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7585-4743","authenticated-orcid":false,"given":"Michael","family":"Marks","sequence":"first","affiliation":[{"name":"Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, United Kingdom"},{"name":"Hospital for Tropical Diseases, University College London Hospitals NHS Trust, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilary","family":"Toloka","sequence":"additional","affiliation":[{"name":"Atoifi Adventist Hospital, Malaita Province, Solomon Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciara","family":"Baker","sequence":"additional","affiliation":[{"name":"Group A Streptococcal Research Group, Murdoch Children\u2019s Research Institute, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Kositz","sequence":"additional","affiliation":[{"name":"Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Asugeni","sequence":"additional","affiliation":[{"name":"Atoifi Adventist Hospital, Malaita Province, Solomon Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliot","family":"Puiahi","sequence":"additional","affiliation":[{"name":"National Referral Hospital, Honiara, Solomon Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowena","family":"Asugeni","sequence":"additional","affiliation":[{"name":"Atoifi Adventist Hospital, Malaita Province, Solomon Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristy","family":"Azzopardi","sequence":"additional","affiliation":[{"name":"Group A Streptococcal Research Group, Murdoch Children\u2019s Research Institute, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Diau","sequence":"additional","affiliation":[{"name":"Atoifi Adventist Hospital, Malaita Province, Solomon Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M","family":"Kaldor","sequence":"additional","affiliation":[{"name":"Kirby Institute, University of New South Wales, Sydney"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Romani","sequence":"additional","affiliation":[{"name":"Kirby Institute, University of New South Wales, Sydney"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Redman-MacLaren","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry, James Cook University, Cairns, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"MacLaren","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry, James Cook University, Cairns, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony W","family":"Solomon","sequence":"additional","affiliation":[{"name":"Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, United Kingdom"},{"name":"Hospital for Tropical Diseases, University College London Hospitals NHS Trust, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C W","family":"Mabey","sequence":"additional","affiliation":[{"name":"Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, United Kingdom"},{"name":"Hospital for Tropical Diseases, University College London Hospitals NHS Trust, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C","family":"Steer","sequence":"additional","affiliation":[{"name":"National Referral Hospital, Honiara, Solomon Islands"},{"name":"Centre for International Child Health, University of Melbourne, Victoria, Australia"},{"name":"Department of General Medicine, Royal Children\u2019s Hospital, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,7,7]]},"reference":[{"key":"key\n\t\t\t\t2019030423555747200_CIT0001","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1469-0691.2012.03798.x","article-title":"Scabies in the developing world: its prevalence, complications, and management","volume":"18","author":"Hay","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0002","doi-asserted-by":"crossref","first-page":"e467","DOI":"10.1371\/journal.pntd.0000467","article-title":"High burden of impetigo and scabies in a tropical country","volume":"3","author":"Steer","year":"2009","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0003","doi-asserted-by":"crossref","first-page":"e0005437","DOI":"10.1371\/journal.pntd.0005437","article-title":"Complement inhibition by Sarcoptes scabiei protects Streptococcus pyogenes: an in vitro study to unravel the molecular mechanisms behind the poorly understood predilection of S. pyogenes to infect mite-induced skin lesions","volume":"11","author":"Swe","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0004","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/QCO.0b013e3283511d27","article-title":"Streptococcal skin infection and rheumatic heart disease","volume":"25","author":"Parks","year":"2012","journal-title":"Curr Opin Infect Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0005","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/jpc.13851","article-title":"Scabies is strongly associated with acute rheumatic fever in a cohort study of Auckland children","volume":"54","author":"Thornley","year":"2018","journal-title":"J Paediatr Child Health"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0006","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/S1473-3099(17)30636-9","article-title":"Scabies and mortality","volume":"17","author":"Lynar","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0007","first-page":"34","article-title":"Control of scabies, skin sores and haematuria in children in the Solomon Islands: another role for ivermectin","volume":"83","author":"Lawrence","year":"2005","journal-title":"Bull World Health Organ"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0008","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0001-706X(99)00087-X","article-title":"Treatment with ivermectin reduces the high prevalence of scabies in a village in Papua New Guinea","volume":"75","author":"Bockarie","year":"2000","journal-title":"Acta Trop"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0009","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/0140-6736(91)92669-S","article-title":"Community control of scabies: a model based on use of permethrin cream","volume":"337","author":"Taplin","year":"1991","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0010","doi-asserted-by":"crossref","first-page":"e0004246","DOI":"10.1371\/journal.pntd.0004246","article-title":"Long term control of scabies fifteen years after an intensive treatment programme","volume":"9","author":"Marks","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0011","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1056\/NEJMoa1500987","article-title":"Mass drug administration for scabies control in a population with endemic disease","volume":"373","author":"Romani","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0012","volume-title":"Trachoma control: a guide for programme managers","author":"Solomon","year":"2006"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0013","first-page":"189","article-title":"Eradication of yaws: the Morges strategy","volume":"87","year":"2012","journal-title":"Wkly Epidemiol Rec"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0014","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1093\/cid\/cit137","article-title":"Mass distribution of azithromycin for trachoma control is associated with increased risk of azithromycin-resistant Streptococcus pneumoniae carriage in young children 6 months after treatment","volume":"56","author":"Coles","year":"2013","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0015","doi-asserted-by":"crossref","first-page":"e1000377","DOI":"10.1371\/journal.pmed.1000377","article-title":"Antibiotic selection pressure and macrolide resistance in nasopharyngeal Streptococcus pneumoniae: a cluster-randomized clinical trial","volume":"7","author":"Skalet","year":"2010","journal-title":"PLoS Med"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0016","doi-asserted-by":"crossref","first-page":"490","DOI":"10.2471\/BLT.13.133462","article-title":"Mass administration of azithromycin and Streptococcus pneumoniae carriage: cross-sectional surveys in the Gambia","volume":"92","author":"Burr","year":"2014","journal-title":"Bull World Health Organ"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0017","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12866-017-0982-x","article-title":"Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control","volume":"17","author":"Bojang","year":"2017","journal-title":"BMC Microbiol"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0018","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1128\/AAC.47.9.2765-2769.2003","article-title":"Impact of azithromycin administration for trachoma control on the carriage of antibiotic-resistant Streptococcus pneumoniae","volume":"47","author":"Batt","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0019","doi-asserted-by":"crossref","first-page":"e0004803","DOI":"10.1371\/journal.pntd.0004803","article-title":"The prevalence of scabies and impetigo in the Solomon Islands: a population-based survey","volume":"10","author":"Mason","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0020","doi-asserted-by":"crossref","first-page":"e0003452","DOI":"10.1371\/journal.pntd.0003452","article-title":"Scabies and impetigo prevalence and risk factors in Fiji: a national survey","volume":"9","author":"Romani","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0021","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S1473-3099(15)00132-2","article-title":"Prevalence of scabies and impetigo worldwide: a systematic review","volume":"15","author":"Romani","year":"2015","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0022","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4269\/ajtmh.14-0438","article-title":"Mapping the epidemiology of yaws in the Solomon Islands: a cluster randomized survey","volume":"92","author":"Marks","year":"2015","journal-title":"Am J Trop Med Hyg"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0023","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/09286586.2016.1238946","article-title":"Mapping trachoma in the Solomon Islands: results of three baseline population-based prevalence surveys conducted with the global trachoma mapping project","volume":"23","author":"Sokana","year":"2016","journal-title":"Ophthalmic Epidemiol"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0024","doi-asserted-by":"crossref","first-page":"e0004071","DOI":"10.1371\/journal.pntd.0004071","article-title":"Trachoma and Yaws: common ground","volume":"9","author":"Solomon","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0025","doi-asserted-by":"crossref","first-page":"e2221","DOI":"10.1371\/journal.pntd.0002221","article-title":"A cluster randomized study of the safety of integrated treatment of trachoma and lymphatic filariasis in children and adults in Sikasso, Mali","volume":"7","author":"Coulibaly","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0026","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.4269\/ajtmh.2007.76.1153","article-title":"Pharmacokinetics of azithromycin and the combination of ivermectin and albendazole when administered alone and concurrently in healthy volunteers","volume":"76","author":"Amsden","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0027","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2471\/BLT.08.052712","article-title":"Validation of an integrated management of childhood illness algorithm for managing common skin conditions in Fiji","volume":"87","author":"Steer","year":"2009","journal-title":"Bull World Health Organ"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0028","doi-asserted-by":"crossref","first-page":"e2654","DOI":"10.1371\/journal.pntd.0002654","article-title":"Electronic data capture tools for global health programs: evolution of LINKS, an Android-, web-based system","volume":"8","author":"Pavluck","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0029","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S0140-6736(11)61624-3","article-title":"Single-dose azithromycin versus benzathine benzylpenicillin for treatment of yaws in children in Papua New Guinea: an open-label, non-inferiority, randomised trial","volume":"379","author":"Mitj\u00e0","year":"2012","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0030","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1056\/NEJMoa1408586","article-title":"Mass treatment with single-dose azithromycin for yaws","volume":"372","author":"Mitj\u00e0","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0031","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1128\/JCM.00312-09","article-title":"Emm and C-repeat region molecular typing of beta-hemolytic streptococci in a tropical country: implications for vaccine development","volume":"47","author":"Steer","year":"2009","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0032","volume-title":"M100Ed28 | Performance Standards for Antimicrobial Susceptibility Testing, 28th Edition"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0033","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1371\/journal.pone.0000010","article-title":"Differences between Belgian and Brazilian group A streptococcus epidemiologic landscape","volume":"1","author":"Smeesters","year":"2006","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0034","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1093\/infdis\/jiu260","article-title":"A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development","volume":"210","author":"Sanderson-Smith","year":"2014","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0035","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1136\/bmj.326.7382.219","article-title":"Interaction revisited: the difference between two estimates","volume":"326","author":"Altman","year":"2003","journal-title":"BMJ"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0036","volume-title":"R: A language and environment for statistical computing","year":"2017"},{"key":"key\n\t\t\t\t2019030423555747200_CIT0037"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/68\/6\/927\/28009264\/ciy574.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T23:56:10Z","timestamp":1551743770000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/68\/6\/927\/5050403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,7]]},"references-count":37,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2018,7,7]]},"published-print":{"date-parts":[[2019,3,5]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciy574","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,3,15]]},"published":{"date-parts":[[2018,7,7]]}}}